Rachel P. Rosovsky
Harvard University
CancerInternal medicineSurgeryOncologyOdds ratioCardiologyRandomized controlled trialIntensive care medicineEmergency medicinePulmonary embolismWarfarinHeparinAnticoagulantRivaroxabanMEDLINEEmergency departmentThrombosisPopulationVenous thromboembolismCoronavirus disease 2019 (COVID-19)Incidence (epidemiology)Clinical trialMedicineGastroenterology
Publications 97
#1Isaac A. Klein (Harvard University)H-Index: 19
#2Shoshana M. Rosenberg (Harvard University)H-Index: 18
Last. Ann H. Partridge (Harvard University)H-Index: 78
view all 22 authors...
Background Early reports suggested increased mortality from COVID-19 in patients with cancer but lacked rigorous comparisons to non-cancer patients. We investigated whether a current cancer diagnosis or cancer history is an independent risk factor for death in hospitalized COVID-19 patients. Patients and methods We identified patients with a history of cancer admitted to 2 large hospitals between 3/13/2020 and 5/10/2020 with laboratory-confirmed COVID-19 and matched them 1:2 to patients without ...
#1Paul Endres (Harvard University)H-Index: 4
#2Rachel P. Rosovsky (Harvard University)H-Index: 20
Last. Andrew S. Allegretti (Harvard University)H-Index: 13
view all 19 authors...
Coronavirus disease 2019 (COVID-19) appears to be associated with increased arterial and venous thromboembolic disease. These presumed abnormalities in hemostasis have been associated with filter clotting during continuous renal replacement therapy (CRRT). We aimed to characterize the burden of CRRT filter clotting in COVID-19 infection and to describe a CRRT anticoagulation protocol that used anti-factor Xa levels for systemic heparin dosing. Multi-center study of consecutive patients with COVI...
4 CitationsSource
#1Leyre Zubiri (Harvard University)H-Index: 13
#2Rachel P. Rosovsky (Harvard University)H-Index: 20
Last. Kerry L. Reynolds (Harvard University)H-Index: 22
view all 17 authors...
Background The Coronavirus Disease-2019 (COVID-19) pandemic has significantly impacted healthcare systems. However, to date, the trend of hospitalizations in the oncology patient population has not been studied and the frequency of nosocomial spread to cancer patients is not well-understood. The objectives of this study were to evaluate the impact of COVID-19 on inpatient oncology census and determine the nosocomial rate of COVID-19 in cancer patients admitted at a large academic center. Materia...
#1Henrietta Afari (Harvard University)H-Index: 3
#2Leben Tefera (Cleveland Clinic)
Last. Rachel P. Rosovsky (Harvard University)H-Index: 20
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Emerging evidence suggests that novel COVID-19 is associated with increased prothrombotic state and risk of thromboembolic complications, particularly in severe disease. COVID-19 is known to predispose to both venous and arterial thrombotic disease. We describe a case of a 61-year-old woman with history of type II diabetes, hypertension and hyperlipidaemia who presented with dry cough and acute abdominal pain. She was found to have a significantly elevated D-dimer, prompting imaging that showed ...
#1Petros Grivas (Fred Hutchinson Cancer Research Center)H-Index: 22
#2Ali Raza Khaki (Fred Hutchinson Cancer Research Center)H-Index: 8
Last. GdL. Lopes (UM: University of Miami)H-Index: 1
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Background Patients with cancer may be at high risk of adverse outcomes from SARS-CoV-2 infection. We analyzed a cohort of patients with cancer and COVID-19 reported to the COVID-19 and Cancer Consortium (CCC19) to identify prognostic clinical factors, including laboratory measurements and anti-cancer therapies. Patients and methods Patients with active or historical cancer and a laboratory-confirmed SARS-CoV-2 diagnosis recorded between March 17-November 18, 2020 were included. The primary outc...
5 CitationsSource
#1Manila Gaddh (Emory University)H-Index: 10
#2Rachel P. Rosovsky (Harvard University)H-Index: 20
Venous thromboembolism (VTE) is a major cause of morbidity and mortality throughout the world. Up to one half of patients who present with VTE will have an underlying thrombophilic defect. This knowledge has led to a widespread practice of testing for such defects in patients who develop VTE. However, identifying a hereditary thrombophilia by itself does not necessarily change outcomes or dictate therapy. Furthermore, family history of VTE by itself can increase an asymptomatic person's VTE risk...
#1Anahita Dua (Harvard University)H-Index: 18
#2Vikas Thondapu (Harvard University)H-Index: 9
Last. Sandeep Hedgire (Harvard University)H-Index: 16
view all 13 authors...
Abstract: Objectives There are no societal ultrasound guidelines detailing appropriate patient selection for deep vein thrombosis (DVT) imaging in COVID-19 patients nor are there protocol recommendations aimed at decreasing exposure time for ultrasound technologists. We aimed to provide COVID-19 specific protocol optimization recommendations limiting ultrasound technologist exposure while optimizing patient selection. Methods A novel two-pronged algorithm was implemented to limit the DVT ultraso...
1 CitationsSource
#1Chiara Arru (Harvard University)H-Index: 4
#2Subba R. Digumarthy (Harvard University)H-Index: 38
Last. Mannudeep K. Kalra (Harvard University)H-Index: 64
view all 10 authors...
Abstract Aim To assess differences in qualitative and quantitative parameters of pulmonary perfusion from dual-energy computed tomography (CT) pulmonary angiography (DECT-PA) in patients with COVID-19 pneumonia with and without pulmonary embolism (PE). Materials and methods This retrospective institutional review board-approved study included 74 patients (mean age 61 ± 18 years, male:female 34:40) with COVID-19 pneumonia in two countries (one with 68 patients, and the other with six patients) wh...