Yoshihisa Ishiura
Kansai Medical University
CancerInternal medicineEndocrinologyPathologyOncologyImmunologyPlaceboAsthmaLung cancerAntagonistInhalationBronchoalveolar lavageCapsaicinBronchoconstrictionMethacholineNon small cellCough reflexAnesthesiaMedicinePharmacology
90Publications
17H-index
811Citations
Publications 90
Newest
#1Akihiro ItoH-Index: 25
#2Yoshihiro Yamamoto (University of Toyama)H-Index: 31
Last. Kazuhiro Tateda (Toho University)H-Index: 35
view all 22 authors...
Abstract Objectives The aim of this study was to evaluate the diagnostic utility of a novel test kit that could theoretically detect all serogroups of Legionella pneumophila for diagnosing Legionella pneumonia, in comparison with existing kits. Methods This study was conducted in 16 hospitals in Japan from April 2016 to December 2018. Three urinary antigen test kits were used: the novel kit (LAC-116), BinaxNOW Legionella (Binax), and Q-line Kyokutou Legionella (Q-line). In addition, sputum cultu...
1 CitationsSource
#1Yoshihisa Ishiura (Kansai Medical University)H-Index: 1
#1Yoshihisa Ishiura (Kansai Medical University)H-Index: 17
Last. Shosaku Nomura (Kansai Medical University)H-Index: 52
view all 10 authors...
Purpose: Asthma-chronic obstructive pulmonary disease overlap (ACO), characterized by airway limitation, is an important condition with high incidence and mortality. Although some guidelines recommend triple therapy with inhaled corticosteroids/long-acting muscarinic antagonists/long-acting beta2 agonists, this treatment approach is based on the extrapolation of data from studies of asthma or chronic obstructive pulmonary disease (COPD) alone. Methods: A 12-week, randomized, open-label cross-ove...
3 CitationsSource
#1Aya Nakaya (Kansai Medical University)H-Index: 8
#1Aya NakayaH-Index: 2
Last. Shosaku Nomura (Kansai Medical University)H-Index: 52
view all 9 authors...
: We report the case of a man who developed myelodysplastic syndrome (MDS) and refractory cytopenia of unilineage dysplasia, 5 months after aortic valve replacement surgery. He also developed fever of unknown origin. After bone marrow- and other laboratory examinations, he was diagnosed with tuberculosis.
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#1Yoshihisa Ishiura (Kansai Medical University)H-Index: 17
#2Masaki Fujimura (Kanazawa University)H-Index: 53
Last. Shosaku Nomura (Kansai Medical University)H-Index: 52
view all 9 authors...
OBJECTIVE: Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) is of increasing interest because ACO patients have significantly worse outcomes, leading to greater social and economic burdens compared with asthma or COPD alone. Some guidelines for ACO recommend triple therapy with inhaled corticosteroids, long-acting β2 agonists, and long-acting muscarinic antagonists. However, this approach is based on extrapolating data from patients with asthma or COPD alone. Therapeutic studies...
9 CitationsSource
#1Masayoshi Hosaka (Kyoto University)H-Index: 1
#2Ichiro Arai (Nihon Pharmaceutical University)H-Index: 5
Last. Yoshiharu Motoo (Kanazawa Medical University)H-Index: 37
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Background The Japan Society for Oriental Medicine makes a compilation of structured abstracts of randomized controlled trials (RCTs) of Kampo medicines available on its Evidence Reports of Kampo Treatment (EKAT) website.
4 CitationsSource
: An increasing number of patients with lung cancer are undergoing outpatient chemotherapy, and thus, it is very important to maintain the quality of life(QOL)of these patients. Ninjin-Youei-To(TJ-108), a Japanese traditional medicine, has been reported to improve the QOL of patients with advanced cancer. However, the effect of TJ-108 in patients with lung cancer undergoing outpatient chemotherapy is unknown. Therefore, we conducted this study. To investigate factors influencing the QOL of these...
#1Yoshihisa Ishiura (Kansai Medical University)H-Index: 17
#2Masaki FujimuraH-Index: 53
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 7 authors...
Background Asthma in the elderly population has been focused because it affects quality of life and results in a higher hospitalization rate and mortality. Fluticasone furoate (FF)/vilanterole (VI) is a novel inhaled corticosteroids (ICS)/long-acting β2 agonist (LABA) combination being developed for once-daily administration for asthma with greater anti-inflammatory activity and longer duration of bronchidilation. The ElliptaTM dry powder inhaler (DPI) has also been available as a new device wit...
7 CitationsSource
#1Johsuke Hara (Kanazawa University)H-Index: 12
#2Masaki FujimuraH-Index: 53
Last. Kazuo Kasahara (Kanazawa University)H-Index: 28
view all 14 authors...
ABSTRACTBackground: We demonstrated that heightened cough response to bronchoconstriction is a fundamental feature of cough variant asthma (CVA). To evaluate this physiological feature of CVA in daily clinical practice, it is necessary to clarify the cough response to bronchoconstriction in healthy subjects. We evaluated cough response to methacholine (MCh)-induced bronchoconstriction in healthy subjects. A forced oscillometry technique was used to measure airway resistance changes with Mch. Met...
3 CitationsSource
#1Johsuke HaraH-Index: 12
#2Tamami SakaiH-Index: 3
Last. Masaki FujimuraH-Index: 53
view all 12 authors...
Johsuke Hara1*, Tamami Sakai1, Taro Yoneda1, HayatoKoba1, Keigo Saeki2, Mayuko Tani2, Noriyuki Ohkura1, Takashi Sone1, Hideharu Kimura1, Yoshihisa Ishiura3, Kazuo Kasahara1 and Masaki Fujimura4 1Respiratory Medicine, Kanazawa University Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa, Ishikawa, Japan 2Internal Medicine, Keiju Medical Center, Nanao, Ishikawa, Japan 3Respiratory Medicine, Toyama City Hospital, Toyama, Toyama, Japan 4Respiratory Medicine, Nat...
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An increasing number of patients with lung cancer are undergoing outpatient chemotherapy.It is very important to retain the quality of life (QOL) of these patients.Japanese traditional medicine, TJ-48, has been reported to improve the QOL of patients with advanced cancer. However, the effect of TJ-48 in patients with lung cancer undergoing outpatient chemotherapy is unknown. The present study was conducted to investigate the factors influencing the QOL of these patients. We used "The QOL questio...
7 Citations