Pantelis A. Sarafidis
Aristotle University of Thessaloniki
Internal medicineEndocrinologySurgeryAmbulatory blood pressureRenal functionCardiologyRandomized controlled trialIntensive care medicineArterial stiffnessInsulin resistanceHemodialysisKidney diseaseDiseaseDialysisKidneyPopulationIn patientAmbulatoryDiabetes mellitusMedicineBlood pressure
379Publications
48H-index
6,489Citations
Publications 372
Newest
#1Carmine ZoccaliH-Index: 112
#2Claudia Torino (National Research Council)H-Index: 19
Last. Danilo Fliser (Saarland University)H-Index: 74
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Lung congestion, estimated by lung ultrasound is a risk factor for all-cause and cardiovascular mortality in patients on chronic hemodialysis and may be useful to guide ultrafiltration and drug therapy in this population. In an international, multi-center randomized controlled trial (NCT02310061) we investigated whether a lung ultrasound-guided treatment strategy improved a composite end point (all-cause death, non-fatal myocardial infarction, decompensated heart failure) vs usual care in patien...
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#1Mehmet Kanbay (Koç University)H-Index: 61
#2Atalay Demiray (Koç University)H-Index: 1
Last. Peter Rossing (UCPH: University of Copenhagen)H-Index: 100
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Sodium-glucose cotransporter type 2 inhibitors (SGLT2i) are promising drugs to treat chronic kidney disease (CKD) patients with or without diabetes mellitus (DM). Besides improving glycemic control, SGLT2i are cardioprotective and kidney protective and decrease body weight, serum uric acid, blood pressure, albuminuria and glomerular hyperfiltration. These effects may benefit graft function and survival in kidney transplant (KT) patients. In this review, we evaluate data on the efficacy and safet...
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#1Jose M. ValdivielsoH-Index: 32
#2Olga Balafa (UoI: University of Ioannina)H-Index: 11
Last. Alberto OrtizH-Index: 102
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Despite recent therapeutic advances, chronic kidney disease (CKD) is one of the fastest growing global causes of death. This illustrates limitations of current therapeutic approaches and, potentially, unidentified knowledge gaps. For decades, renin-angiotensin-aldosterone system (RAAS) blockers have been the mainstay of therapy for CKD. However, they favor the development of hyperkalemia, which is already common in CKD patients due to the CKD-associated decrease in urinary potassium (K+) excreti...
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#1Maria KorogiannouH-Index: 2
#2Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
Last. Smaragdi MarinakiH-Index: 4
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INTRODUCTION Hypertension is the most prominent risk factor in kidney transplant recipients (KTRs). No study so far assessed in parallel the prevalence, control, and phenotypes of blood pressure (BP) or the accuracy of currently recommended office BP diagnostic thresholds in diagnosing elevated ambulatory BP in KTRs. METHODS 205 stable KTRs underwent office BP measurements and 24-h ambulatory BP monitoring (ABPM). Hypertension was defined as follows: (1) office BP ≥140/90 mm Hg or use of antihyp...
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#1Maria-Eleni Alexandrou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 2
#2Marieta Theodorakopoulou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 3
Last. Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
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Aim null The burden of several cardiovascular risk factors increases in parallel to renal function decline. Exercise intolerance is common in patients with chronic kidney disease (CKD) and has been associated with increased risk of adverse outcomes. Whether indices of cardiorespiratory capacity deteriorate with advancing CKD stages is unknown. null Methods null We conducted a systematic review and meta-analysis of studies assessing cardiorespiratory capacity in adult patients with pre-dialysis C...
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#1Charalampos Loutradis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 14
#2Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
Last. Carmine ZoccaliH-Index: 112
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OBJECTIVES Hypertension is highly prevalent and independently associated with adverse outcomes in patients undergoing hemodialysis. Volume overload is the main mechanism of increased blood pressure (BP) in these individuals. This study examines the long-term effects of dry-weight reduction with a standardized lung-ultrasound (US)-guided strategy on ambulatory BP in hypertensive hemodialysis patients. METHODS This is the report of the 12-month follow-up of a randomized controlled trial in 71 clin...
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#1Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
#2Danai Faitatzidou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 3
Last. Aikaterini Papagianni (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 21
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Although the ability of individuals with end-stage renal disease to maintain body homoeostasis is equally impaired during all weekdays, conventional haemodialysis (HD) treatment is scheduled thrice weekly, containing two short and one long interdialytic interval. This intermittent nature of HD and the consequent fluctuations in volume, metabolic parameters and electrolytes have long been hypothesized to predispose to complications. Large observational studies link the first weekday with an incre...
4 CitationsSource
#1Marieta Theodorakopoulou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 3
#2Afroditi K. BoutouH-Index: 11
Last. Pantelis A. Sarafidis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 48
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Patients with kidney failure often present with reduced cardiovascular functional reserve and exercise tolerance. Previous studies on cardiorespiratory fitness examined with cardiopulmonary-exercise-testing (CPET) in kidney-transplant-recipients (KTR) had variable results. This is a systematic review and meta-analysis of studies examining cardiovascular functional reserve with CPET in KTR in comparison to patients with kidney failure (CKD-Stage-5 before dialysis, hemodialysis or peritoneal dialy...
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#1Marieta Theodorakopoulou (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 3
Last. Pantelis A. SarafidisH-Index: 48
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