Fergal D. Malone
Rotunda Hospital
Internal medicineObstetricsEndocrinologyFetusPediatricsProspective cohort studyPreeclampsiaPrenatal diagnosisGestational ageIntrauterine growth restrictionPregnancyAneuploidyDown syndromePopulationGynecologyFirst trimesterGestationBirth weightMedicineCohort
501Publications
62H-index
11kCitations
Publications 487
Newest
#1Russell L. Deter (BCM: Baylor College of Medicine)H-Index: 38
#2Wesley Lee (BCM: Baylor College of Medicine)H-Index: 32
Last. Karen Flood (RCSI: Royal College of Surgeons in Ireland)H-Index: 9
view all 7 authors...
OBJECTIVE We have previously shown that 3rd trimester growth in small fetuses (EFW 10th percentile are also variable but in different ways. METHODS This investigation was carried out on 191 fetuses/neonates derived from the PORTO study with EFW 10th percentile. Composite size parameters were used to quantify growth pathology at individual third trimester time points (individual composite Prenatal Growth Assessment Score {-icPGAS}). The Fetal Growth Pathology Score 1 (-FGPS1), calculated cumulati...
Source
#1Cilian Ó Maoldomhnaigh (Trinity College, Dublin)H-Index: 2
#2Donal J. Cox (Trinity College, Dublin)H-Index: 6
Last. Sharee A. Basdeo (Trinity College, Dublin)H-Index: 10
view all 6 authors...
The Warburg effect, defined as increased glycolysis and decreased oxidative phosphorylation, occurs in murine macrophages following LPS stimulation and is required for activation. There are differences between human and murine macrophage metabolic responses to stimulation, with peak metabolite concentrations occurring earlier in humans than mice. Complex changes occur in the human immune system with age, resulting in the very young and the very old being more susceptible to infections. Anti-bact...
Source
Source
#1Daniel Kane (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
#2Mary E. D'Alton (CUMC: Columbia University Medical Center)H-Index: 67
Last. Fergal D. Malone (RCSI: Royal College of Surgeons in Ireland)H-Index: 62
view all 3 authors...
Objective To evaluate the performance of first trimester combined screening for the detection of rare chromosomal abnormalities, other than Trisomies 21, 18 or 13 or 45 × . Study design A database containing 36,254 pregnancies was analyzed. These patients were recruited at 15 US centers and included singleton pregnancies from 10 3/7-13 6/7 weeks. All patients had a nuchal translucency (NT) scan and those without a cystic hygroma (N = 36,120) underwent a combined first trimester screening test ('...
Source
#1Joanna Griffin (Rotunda Hospital)H-Index: 4
#2Elizabeth Tully (RCSI: Royal College of Surgeons in Ireland)H-Index: 12
Last. Fergal D. Malone (Rotunda Hospital)H-Index: 62
view all 13 authors...
Abstract Objectives:This study examined the natural history, including incidence and prevalence, of SARS-CoV-2 antibodies serially up to 6 months post infection in Irish Healthcare Workers (HCW) at a large urban academic obstetric unit, during the first pandemic peak from March to September 2020. Design: This single centre observational study profiled SARS-CoV-2 incidence and infection rates using viral RNA detected using oro/naso-pharyngeal swabs accompanied by serological assessment of study p...
Source
#1Pe'er DarH-Index: 13
#2Bo JacobssonH-Index: 61
Last. Mary E. NortonH-Index: 59
view all 19 authors...
Source
#1Pe'er DarH-Index: 13
#2Bo JacobssonH-Index: 61
Last. Mary E. NortonH-Index: 59
view all 19 authors...
Source
#1Catherine Finnegan (RCSI: Royal College of Surgeons in Ireland)H-Index: 1
#2Suzanne Smyth (RCSI: Royal College of Surgeons in Ireland)
Last. Fergal D. Malone (RCSI: Royal College of Surgeons in Ireland)H-Index: 62
view all 5 authors...
Source
Source
#1Daniel Kane (RCSI: Royal College of Surgeons in Ireland)H-Index: 2
#2Ita Shanahan (RCSI: Royal College of Surgeons in Ireland)H-Index: 1
Last. Naomi Burke (RCSI: Royal College of Surgeons in Ireland)H-Index: 5
view all 6 authors...
Abstract Objectives The rate of caesarean section (CS) is increasing globally. The nulliparous, term, singleton, vertex presentation, spontaneously labouring woman (Robson Group 1/RG1) is considered low risk for CS(1,2). It has been hypothesized that more CS occur at night-time or at weekends due to doctor fatigue. The European Working Time Directive (EWTD) was implemented in 2013 to limit doctor working hours, which aimed at reducing fatigue but arguably fractures continuity of care. This study...
Source