Cristina Carresi
Center for Food Safety
EndocrinologyNeuroscienceChemistryAutophagyOxidative stressInsulin resistanceAntioxidantCholesterolCardiotoxicityFatty liverHyperlipidemiaDiseaseMetabolic syndromeSuperoxideEndothelial dysfunctionLipid metabolismBioinformaticsMedicineCell biologyPharmacology
57Publications
15H-index
656Citations
Publications 34
Newest
AIMS Diabetic cardiomyopathy represents the main cause of death among diabetic people. Despite this evidence, the molecular mechanisms triggered by impaired glucose and lipid metabolism inducing heart damage remain unclear. The aim of our study was to investigate the effect of altered metabolism on the early stages of cardiac injury in experimental diabetes. METHODS For this purpose, rats were fed a normocaloric diet (NPD) or a high fat diet (HFD) for up to 12 weeks. After the fourth week, strep...
3 CitationsSource
The high incidence of obesity is associated with an increasing risk of several chronic diseases such as cardiovascular disease, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Sustained obesity is characterized by a chronic and unsolved inflammation of adipose tissue, which leads to a greater expression of proinflammatory adipokines, excessive lipid storage and adipogenesis. The purpose of this review is to clarify how inflammatory mediators act during adipose tissue dysfunction i...
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#1Jessica MaiuoloH-Index: 18
#2Micaela GliozziH-Index: 17
Last. Vincenzo MollaceH-Index: 29
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Different bacterial families colonize most mucosal tissues in the human organism such as the skin, mouth, vagina, respiratory, and gastrointestinal districts. In particular, the mammalian intestine hosts a microbial community of between 1,000 and 1,500 bacterial species, collectively called "microbiota." Co-metabolism between the microbiota and the host system is generated and the symbiotic relationship is mutually beneficial. The balance that is achieved between the microbiota and the host orga...
1 CitationsSource
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#1Cristina CarresiH-Index: 15
#2Miriam ScicchitanoH-Index: 8
Last. Vincenzo MollaceH-Index: 29
view all 16 authors...
Cardiovascular diseases (CVDs), which include congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, and many other cardiac disorders, cause about 30% of deaths globally; representing one of the main health problems worldwide. Among CVDs, ischemic heart diseases (IHDs) are one of the major causes of morbidity and mortality in the world. The onset of IHDs is essentially due to an unbalance between the metabolic demands of the myocardium and its supply of ...
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#1Vincenzo MollaceH-Index: 29
#2Giuseppe M.C. Rosano (Lond: University of London)H-Index: 18
Last. Maurizio VolterraniH-Index: 45
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There is evidence demonstrating that heart failure (HF) occurs in 1–2% of the global population and is often accompanied by comorbidities which contribute to increasing the prevalence of the disease, the rate of hospitalization and the mortality. Although recent advances in both pharmacological and non-pharmacological approaches have led to a significant improvement in clinical outcomes in patients affected by HF, residual unmet needs remain, mostly related to the occurrence of poorly defined st...
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#1Francesca BoscoH-Index: 8
#2Vincenzo MusolinoH-Index: 14
Last. Vincenzo MollaceH-Index: 29
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Abstract Skeletal muscles and bone tissue form the musculoskeletal apparatus, a complex system essential for the voluntary movement. The loss of muscle mass and muscle strength is often associated with a loss of bone mass, in a “hazardous duet” which implies the co-existence of sarcopenia-osteoporosis and exposes patients to a deterioration in quality of life and increased mortality. From the mechanostat theory to the recent definition of the osteosarcopenia syndrome, many aspects of muscle-bone...
1 CitationsSource
#1Micaela GliozziH-Index: 17
#2Vincenzo MusolinoH-Index: 14
Last. Vincenzo MollaceH-Index: 29
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Abstract Cholesterol homeostasis is a highly regulated process in human body because of its several functions underlying the biology of cell membranes, the synthesis of all steroid hormones and bile acids and the need of trafficking lipids destined to cell metabolism. In particular, it has been recognized that peripheral and central nervous system cholesterol metabolism are separated by the blood brain barrier and are regulated independently; indeed, peripherally, it depends on the balance betwe...
2 CitationsSource
#1Roberta MacrìH-Index: 4
#1Roberta Macrì (Magna Græcia University)H-Index: 5
Last. Vincenzo MollaceH-Index: 29
view all 14 authors...
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#1Jessica MaiuoloH-Index: 18
#2Micaela GliozziH-Index: 17
Last. Vincenzo MollaceH-Index: 18
view all 11 authors...
2 CitationsSource