Blair K. Brettmann
Georgia Institute of Technology
MicelleElectrospinningIonStructure formationPolyelectrolyteSolubilityChemical physicsSolvophobicNanotechnologyNanocrystalChemistryMaterials scienceCrystallizationPolyvinylpyrrolidoneChemical engineeringActive ingredientFiberPolymerDissolutionNanofiber
Publications 28
Indomethacin (IM) is a small molecule active pharmaceutical ingredient (API) that exhibits polymorphism with the γ-form being the most thermodynamically stable form of the drug. The α-form is metastable, but it exhibits higher solubility, making it a more attractive form for drug delivery. As with other metastable polymorphs, α-IM undergoes interconversion to the stable form when subjected to certain stimuli, such as solvent, heat, pH, or exposure to seed crystals of the stable form. In this stu...
#1Gill Biesold (Georgia Institute of Technology)H-Index: 1
#2Shuang Liang (Georgia Institute of Technology)H-Index: 3
Last. Zhiqun Lin (Georgia Institute of Technology)H-Index: 72
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Luminescent semiconductor nanocrystals are a fascinating class of materials because of their size-dependent emission. Multitudes of past studies have demonstrated that semiconductor nanoparticles with radii smaller than their Bohr radius experience quantum confinement and thus size-dependent emission. Exerting pressure to these nanoparticles represents an additional, more dynamic, strategy to alter their size and shift their emission. Upon the application of pressure, lattices are strained, and ...
1 CitationsSource
#1Manali Banerjee (Georgia Institute of Technology)H-Index: 4
#2Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
1 CitationsSource
#1Xueqiao WangH-Index: 1
#2Jonathan M YaegerH-Index: 1
Last. Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
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#1Nasreen Khan (Georgia Institute of Technology)H-Index: 1
#2Nadia Z. Zaragoza (Georgia Institute of Technology)
Last. Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
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Polyelectrolytes are used in paper manufacturing to increase flocculation and water drainage and improve mechanical properties. In this study, we examine the interaction between charged cellulosic ...
#1Manali BanerjeeH-Index: 4
#2Sisira SaraswatulaH-Index: 1
Last. Blair K. BrettmannH-Index: 13
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Cellulose nanocrystals (CNCs) are attractive for use in polymer composites, biomedical applications, and barrier packaging. In all of these applications they are mixed with other components and compatibility is a major design consideration, as CNCs naturally have a high density of surface hydroxyl groups and primarily disperse well in polar media. Numerous surface modification approaches have been used to address these issues, but challenges remain due to the variability in the commercially avai...
#1Hannah K. Woods (Georgia Institute of Technology)H-Index: 2
#2Andrew Boddorff (Georgia Institute of Technology)H-Index: 2
Last. Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
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4 CitationsSource
#1Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
#2Narayan Rameesh (TDCC: Dow Chemical Company)
#1Jessica FaubelH-Index: 2
#2Riddhi P. PatelH-Index: 2
Last. Blair K. BrettmannH-Index: 13
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Polyelectrolyte brushes are important stimuli-responsive materials in a variety of technological applications as well as in biological systems. Their small size, however, introduces characterization challenges, particularly in studying 3D structure and time-dependent behavior. In this Letter, we report on the polyelectrolyte brush behavior of extra-large hyaluronan brushes (∼15 μm) recently developed using an enzyme-mediated growth process. In response to increasing ionic strength, the brush dis...
3 CitationsSource
#1Elena Ewaldz (Georgia Institute of Technology)H-Index: 3
#2Blair K. Brettmann (Georgia Institute of Technology)H-Index: 13
Electrospinning is growing as a production technology for many applications, particularly in membranes and tissue engineering. One challenge in electrospinning is the need for high molecular weight polymers, a requirement that often prevents formation of fibers with high proportions of functional materials that may include particles, surfactants, cells, etc. Molecular interactions between lower molecular weight polymers or molecules can provide similar cohesion in the electrospinning jet as enta...
10 CitationsSource