Nobuaki Miyahara
RMIT University
AirwayInternal medicinePathologyCytotoxic T cellCD8ReceptorChemistryImmunologyAsthmaLeukotriene B4InflammationOvalbuminLungBronchoalveolar lavageAllergenAirway hyperresponsivenessInterleukin 13MedicineBiologyAdoptive cell transfer
Publications 153
#1Eri Ando (Okayama University)
#2Takamasa Nakasuka (Okayama University)H-Index: 4
Last. Katsuyuki Hotta (Okayama University)H-Index: 39
view all 15 authors...
A 16-year-old boy with asthma participated in recovery volunteer work following the 2018 heavy rains in Japan. One month later, he experienced chest pain and dyspnea. Chest computed tomography revealed a cavity with a fungal ball, and Aspergillus fumigatus was detected in his bronchoalveolar lavage fluid. He was treated with voriconazole, but new consolidations appeared rapidly. He also experienced allergic bronchopulmonary aspergillosis. After prednisolone prescription, the consolidations impro...
#1Hisao HigoH-Index: 6
#2Kadoaki OhashiH-Index: 1
Last. Kazuya NishiiH-Index: 5
view all 18 authors...
#1Daisuke Morichika (Okayama University)H-Index: 8
#2Akihiko Taniguchi (Okayama University)H-Index: 10
Last. Masayuki Hanaoka (Shinshu University)H-Index: 28
view all 15 authors...
Background IL-33, which is known to induce type 2 immune responses via group 2 innate lymphoid cells, has been reported to contribute to neutrophilic airway inflammation in chronic obstructive pulmonary disease. However, its role in the pathogenesis of emphysema remains unclear. Methods We determined the role of interleukin (IL)-33 in the development of emphysema using porcine pancreas elastase (PPE) and cigarette smoke extract (CSE) in mice. First, IL-33-/- mice and wild-type (WT) mice were giv...
#1Toshiyuki AokageH-Index: 10
#2Mizuki SeyaH-Index: 1
Last. Hiromichi NaitoH-Index: 10
view all 12 authors...
#2Eiki Ichihara (Okayama University)H-Index: 21
Last. Daizo KishinoH-Index: 12
view all 6 authors...
#2Naohiro OdaH-Index: 8
Last. Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
view all 9 authors...
Abstract Cryptococcosis is an invasive mycosis that has become increasingly prevalent in immunocompromised patients. Pregnant women are also one of the risk populations for cryptococcosis. Reversal of Th2 to Th1 response following resolution of immunosuppression during the postpartum period can lead to overt clinical manifestations of a previously silent infection, resembling an immune reconstitution inflammatory syndrome. Here, we report a case of a 30-year-old woman who had an exacerbation of ...
#1Sachi Okawa (Okayama University)H-Index: 3
#1Sachi Okawa (Okayama University)
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
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A 68-year-old man presented with a solid mass at the left renal pelvis and ureter with multiple systemic lymphadenopathies and a mass with a cavity in the right lower lobe of the lung. While a transbronchial lung biopsy revealed no malignancy, a biopsy of the renal pelvis showed marginal zone lymphoma with polyclonal IgG4-positive cells. The serum IgG4 level and presence of a bilateral orbital mass suggested Mikulicz disease.The lesions shrank following the administration of steroids. A rebiopsy...
#1Junko Itano (Okayama University)H-Index: 4
#2Yasushi TanimotoH-Index: 21
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
view all 10 authors...
Hermansky-Pudlak syndrome (HPS) is an autosomal recessive hereditary disease that may be complicated by progressive and potentially fatal interstitial pneumonia. We herein report a 64-year-old woman with interstitial pneumonia associated with HPS type 4 whom we treated with nintedanib after pirfenidone proved ineffective. To our knowledge, there have been no previous reports of nintedanib being used to treat a patient with HPS type 4. There is a need for clinical trials of antifibrotic agents, i...
#1Naohiro Oda (Okayama University)H-Index: 8
#2Yoshinobu Maeda (Okayama University)H-Index: 29
Last. Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
view all 4 authors...
A 63-year-old asymptomatic woman with abnormal chest shadow was referred to our hospital. The patient was a never smoker, and had a history of bronchial asthma and hypertension. Chest CT revealed a 4 cm diameter tumour in the right upper lobe, two nodules accompanied spicula and pleural indentation
1 CitationsSource
#1Kota Araki (Okayama University)H-Index: 4
#2Rie Kinoshita (Okayama University)H-Index: 11
Last. Masakiyo Sakaguchi (Okayama University)H-Index: 50
view all 21 authors...
In patients with interstitial pneumonia, pulmonary fibrosis is an irreversible condition that can cause respiratory failure. Novel treatments for pulmonary fibrosis are necessary. Inflammation is thought to activate lung fibroblasts, resulting in pulmonary fibrosis. Of the known inflammatory molecules, we have focused on S100A8/A9 from the onset of inflammation to the subsequent progression of inflammation. Our findings confirmed the high expression of S100A8/A9 in specimens from patients with p...
2 CitationsSource