Yasuni Nakanuma
Kanazawa University
PathologyImmunologyImmunohistochemistryBiliary tractHepatolithiasisCirrhosisCarcinomaHepatocellular carcinomaAutopsyBile ductPrimary biliary cirrhosisPrimary sclerosing cholangitisIntrahepatic bile ductsAdenocarcinomaIntrahepatic CholangiocarcinomaBiliary cirrhosisHepatologyMedicineBiologyGastroenterology
874Publications
87H-index
36.1kCitations
Publications 864
Newest
#1Hiep Nguyen Canh (Kanazawa University)H-Index: 2
#2Kenta Takahashi (Kanazawa University)H-Index: 1
Last. Kenichi Harada (Kanazawa University)H-Index: 52
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AIMS Mass-forming intrahepatic cholangiocarcinomas (MF-iCCAs), involving small bile ducts, bile ductules, or canals of Hering, remain treated as a single entity. We aimed to examine the diversity in histology, phenotype, and tumor vasculature of MF-iCCAs. METHODS AND RESULTS Based on morphology and immunophenotype, we classified MF-iCCAs into small bile duct (SBD), cholangiolocarcinoma (CLC), ductal plate malformation (DPM), and hepatocellular carcinoma (HCC)-like subtypes. Genetic correlations ...
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#1Yasuni NakanumaH-Index: 87
#2Katsuhiko UesakaH-Index: 40
Last. Young Nyun Park (Yonsei University)H-Index: 59
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The pathological spectrum of intraductal papillary neoplasm (IPNB) remains to be clarified. A total of 186 IPNBs were pathologically examined using the type 1 and 2 subclassifications proposed by Japanese and Korean biliary pathologists incorporating a two-tiered grading system (low-grade and high-grade dysplasia), with reference to four subtypes (intestinal (i), gastric (g), pancreatobiliary (pb) and concocytic (o) subtype). IPNBs were classifiable into type 1 composed of low-grade dysplasia an...
1 CitationsSource
#1Rosanna Asselta (Humanitas University)H-Index: 37
#2Elvezia Maria Paraboschi (Humanitas University)H-Index: 15
Last. Pietro Invernizzi (University of Milano-Bicocca)H-Index: 63
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ABSTRACT Background & aims Genome-wide association studies (GWAS) in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually-dimorphic complex autoimmune disease. Methods We performed a chrX-wide association study (XWAS), including genotype data from five GWAS (from Italy, UK, Canada, China, Japan; 5,244 cases, 11,875 controls). Results Single-marker association analyses...
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Abstract Intracholecystic papillary neoplasm (ICPN) is a recently proposed gallbladder neoplasm. Its prevalence and pathologies remain to be clarified. A total of 38 ICPN cases (28 ICPNs identified among 1904 cholecystectomies (1.5%) and in 100 surgically resected primary gallbladder neoplasms (28%) in Fukui Prefecture Saiseikai Hospital, Japan, and other 10 ICPNs) were examined pathologically and immunohistochemically. They were composed of 21 males and 17 females with a mean age of 75 years ol...
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#1Motoko Sasaki (Kanazawa University)H-Index: 45
#2Yasunori Sato (Kanazawa University)H-Index: 38
Last. Yasuni NakanumaH-Index: 87
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#1Yasuni NakanumaH-Index: 87
#2Katsuhiko UesakaH-Index: 40
Last. Takuro TeradaH-Index: 2
view all 9 authors...
2 CitationsSource
#1Keiichi Kubota (Dokkyo Medical University)H-Index: 46
#2Jin-Young Jang (Seoul National University Hospital)H-Index: 40
Last. Michiaki Unno (Tohoku University)H-Index: 54
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BACKGROUND The prevalent location and incidence of intraductal papillary neoplasm of the bile duct (IPNB) and invasive carcinoma associated with them have varied markedly among studies due to differences in diagnostic criteria and tumor location. METHODS IPNBs were classified into two types: Type 1 IPNB, being histologically similar to intraductal papillary-mucinous neoplasm of the pancreas, and Type 2 IPNB, having a more complex histological architecture with irregular papillary branching or fo...
5 CitationsSource
#2Takuro TeradaH-Index: 2
Last. Yasuni NakanumaH-Index: 87
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Heterotopic pancreas (HP) is defined as pancreatic tissue in organs with no anatomical continuity with the orthotopic pancreas. Based on the number of cases reported in the literature between the year 2000 and 2020, HP is rarely found causing malignant transformation of the duodenum. We herein report a case of adenocarcinoma arising from the HP in the first portion of the duodenum. A 77-year-old Japanese man presented to our hospital with epigastric pain. Despite having undergone laparoscopic su...
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#1Yasuni NakanumaH-Index: 87
#2Katsuhiko UesakaH-Index: 40
Last. Young Nyun Park (Yonsei University)H-Index: 59
view all 13 authors...
Intraductal papillary neoplasms of bile duct (IPNBs) remain a challenging entity to manage. The pathologic spectrum of 34 gastric subtype of IPNB (gIPNB) cases was examined in consideration of the type 1 and 2 subclassification proposed by Japan-Korea consensus and compared with gastric subtype of pancreatic intraductal papillary mucinous neoplasm (gIPMN) (44 cases). Type 1 gIPNBs (17 cases) showed regular papillary foveola with variable tubular pyloric glands. Eight of the type 1 gIPNBs showed ...
2 CitationsSource
Background The objective was to clarify the prognostic impact of the 8th edition of American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) of intrahepatic cholangiocarcinoma (ICC).
4 CitationsSource