Yasushi Tanimoto
Okayama University
HistamineInternal medicineRadiologyPeripheral blood mononuclear cellSurgeryPathologyMolecular biologyImmunologyAsthmaRespiratory diseaseLung cancerChemotherapyInflammationOvalbuminExacerbationBasophilLungBronchoalveolar lavageSarcoidosisMedicineBiologyGastroenterology
100Publications
21H-index
1,108Citations
Publications 101
Newest
We herein report a rare case of fast-growing benign metastasizing leiomyoma. A 52-year-old woman was admitted to our hospital with abnormal chest shadows. Chest computed tomography showed well-circumscribed cystic tumors. Because malignancy could not be clearly distinguished in fast-growing tumors, video-assisted thoracic surgery was performed. The pathological findings revealed many cysts and the proliferation of smooth muscle cells. According to the Stanford criteria, the tumor was diagnosed a...
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We herein report the first case of low-dose oxygen therapy for pneumatosis cystoides intestinalis (PCI) using PaO2 as a therapeutic index to prevent acute exacerbation of interstitial pneumonia. An 86-year-old man was admitted to our hospital with abdominal distension. PCI was diagnosed by abdominal computed tomography. Low-dose oxygen therapy was started to avoid acute exacerbation of interstitial pneumonia. The oxygen dose was adjusted so that the PaO2 value was approximately 100 mmHg. After s...
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#1Noboru HamadaH-Index: 6
Last. Yasushi TanimotoH-Index: 21
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We experienced a case of the successful treatment of intractable pulmonary aspergillosis with inhaled liposomal amphotericin B (L-AMB) and oral Voriconazole (VRCZ). A 52-year-old man was admitted to our hospital with a fever. Chest computed tomography (CT) revealed an infiltrative shadow. Two separate sputum cultures detected Aspergillus niger. Although we treated the patient with single and combined antifungal agents, the infiltrative shadow worsened. After obtaining sufficient informed consent...
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#1Junko Itano (Okayama University)H-Index: 4
#2Yasushi TanimotoH-Index: 21
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
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Hermansky-Pudlak syndrome (HPS) is an autosomal recessive hereditary disease that may be complicated by progressive and potentially fatal interstitial pneumonia. We herein report a 64-year-old woman with interstitial pneumonia associated with HPS type 4 whom we treated with nintedanib after pirfenidone proved ineffective. To our knowledge, there have been no previous reports of nintedanib being used to treat a patient with HPS type 4. There is a need for clinical trials of antifibrotic agents, i...
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#1Satoru Senoo (Okayama University)H-Index: 5
#2Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
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BACKGROUND Nintedanib is a multi-kinase inhibitor approved for idiopathic pulmonary fibrosis (IPF); however, its efficacy and safety for patients with IPF and restricted pulmonary function remain unclear. Therefore, the objective of this study was to determine the efficacy and safety of nintedanib for patients with IPF and forced vital capacity (FVC) ≤ 50%. METHODS This was a multi-center retrospective study performed by the Okayama Respiratory Disease Study Group. Patients were allocated into F...
2 CitationsSource
#1Hisao Higo (Okayama University)H-Index: 6
#2Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
Last. Katsuyuki Kiura (Okayama University)H-Index: 68
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Abstract Background Pirfenidone suppresses the decline of forced vital capacity (FVC) in patients with idiopathic pulmonary fibrosis (IPF). However, IPF progresses in some patients despite treatment. We analyzed patients with meaningful FVC declines during pirfenidone treatment and explored the factors predictive of disease progression after FVC decline. Methods This study was a retrospective, multicenter, observational study conducted by the Okayama Respiratory Disease Study Group. We defined i...
1 CitationsSource
#1Akio MoriH-Index: 30
#2Satoshi KouyamaH-Index: 1
Last. Reiko KishikawaH-Index: 8
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Introduction: To investigate a role of sputum and serum biomarkers in the diagnosis and treatment of chronic asthma, sputum and serum were simultaneously collected from 200 patients and analyzed in respect to possible correlation with several clinical markers. Methods: Two hundred asthma patients were enrolled from the National Hospital Organization Allergy Group Hospitals. Sputum and serum were simultaneously collected. Twenty five serum proteins including cytokines, chemokines, etc. were assay...
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#1Shoko SonobeH-Index: 2
#2Toru AraiH-Index: 26
Last. Yoshikazu InoueH-Index: 54
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: A 34-year-old woman experiencing shortness of breath was referred to our hospital. The patient was diagnosed with sporadic lymphangioleiomyomatosis based on the observation of bilateral diffuse multiple thin-walled cysts on computed tomography of the chest, chylous effusion, elevated serum vascular endothelial growth factor-D levels and transbronchial biopsy findings. This patient was a hepatitis B virus (HBV) carrier. Treatment with 1 mg daily of sirolimus was started after HBV DNA was brough...
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#1Akihiko TaniguchiH-Index: 10
#2Nobuaki Miyahara (RMIT: RMIT University)H-Index: 33
Last. Katsuyuki KiuraH-Index: 68
view all 12 authors...
Although recent retrospective studies suggested that the use of β-blockers appears to help improve the mortality rate and decrease the rate of exacerbation in chronic obstructive pulmonary disease (COPD) patients with heart failure, the effects of β-blockers on COPD patients without heart failure have not been established. Based on previous reports, we have launched a multicenter, prospective, single-arm phase II study to evaluate the preventive effect of the cardioselective β-blocker bisoprolol...
2 CitationsSource
#1Naohiro Oda (Okayama University)H-Index: 8
#2Nobuaki Miyahara (Okayama University)H-Index: 33
Last. Katsuyuki KiuraH-Index: 68
view all 12 authors...
BACKGROUND: Some recent studies have suggested that beta-blocker use in patients with chronic obstructive pulmonary disease (COPD) is associated with a reduction in the frequency of acute exacerbations. However, the long-term effects of beta-blocker use on lung function of COPD patients have hardly been evaluated. PATIENTS AND METHODS: We retrospectively reviewed 31 Japanese COPD patients taking beta-blockers for >1 year and 72 patients not taking them. The association between beta-blocker use a...
9 CitationsSource