David J. Gracie
University of Leeds
PsychiatryInternal medicineIntensive care medicinePhysical therapyImmunologyInfliximabInflammatory bowel diseaseIrritable bowel syndromeFaecal calprotectinDepression (differential diagnoses)DiseaseComorbidityCrohn's diseaseMEDLINEUlcerative colitisMoodPopulationAnxietyMedicineGastroenterologyMeta-analysis
85Publications
16H-index
1,168Citations
Publications 77
Newest
#1David J. Gracie (University of Leeds)H-Index: 16
#2Alexander C. Ford (University of Leeds)H-Index: 86
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#1David J. Gracie (University of Leeds)H-Index: 16
#2P John Hamlin (University of Leeds)H-Index: 12
Last. Alexander C. Ford (University of Leeds)H-Index: 86
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OBJECTIVES: The impact of irritable bowel syndrome (IBS)-type symptoms on the natural history of inflammatory bowel disease (IBD) is uncertain. We aimed to address this in a longitudinal study of secondary care patients. METHODS: Longitudinal disease activity was defined by disease flare, escalation of medical therapy, hospitalization, or intestinal resection. The number of investigations performed and clinics attended determined healthcare utilization. Psychological well-being and quality of li...
26 CitationsSource
#1Y. Derwa (University of Leeds)H-Index: 4
#2Christopher J.M. Williams (University of Leeds)H-Index: 4
Last. David J. Gracie (University of Leeds)H-Index: 16
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Objectives: Patient-reported symptoms correlate poorly with mucosal inflammation. Clinical decision-making may, therefore, not be based on objective evidence of disease activity. We conducted a study to determine factors associated with clinical decision-making in a secondary care inflammatory bowel disease (IBD) population, using a cross-sectional design. Methods: Decisions to request investigations or escalate medical therapy were recorded from outpatient clinic encounters in a cohort of 276 p...
10 CitationsSource
#1Rebecca Sagar (St James's University Hospital)H-Index: 5
#1Rebecca C SagarH-Index: 4
Last. Christian P. SelingerH-Index: 25
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#1Rebecca Sagar (St James's University Hospital)H-Index: 5
#1Rebecca C Sagar (University of Leeds)H-Index: 4
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
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Background Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder (FGID) characterized by intermittent episodes of nausea and vomiting. Our aim was to report its prevalence and associated features. Methods Data concerning demographics, symptoms, and psychiatric comorbidity were collected. Symptoms compatible with CVS were classified as per Rome III criteria. We recorded whether a diagnosis of CVS was considered in patients after negative investigation. We compared demographics ...
17 CitationsSource
BACKGROUND: Virtual biologics clinics are often used to review patients with inflammatory bowel disease receiving biological therapy, with decisions whether to continue, switch, or stop therapy made based on review of symptoms, disease history, and investigations. We aimed to investigate whether therapeutic drug monitoring of infliximab (IFX) trough levels and anti-drug antibodies influences decision making within a virtual biologics clinic. METHODS: For all patients with inflammatory bowel dise...
10 CitationsSource
#1Raguprakash Ratnakumaran (University of Leeds)H-Index: 5
#2Lisa WarrenH-Index: 7
Last. Alexander C. Ford (University of Leeds)H-Index: 86
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7 CitationsSource
#1Andrew P. ViggarsH-Index: 1
#2David J. GracieH-Index: 16
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
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2 CitationsSource
#1David J. Gracie (St James's University Hospital)H-Index: 16
#2Alexander C. Ford (St James's University Hospital)H-Index: 86
3 CitationsSource
#1John Headlam (St James's University Hospital)H-Index: 1
#2Alexander C. Ford (St James's University Hospital)H-Index: 86
Last. David J. Gracie (St James's University Hospital)H-Index: 16
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1 CitationsSource