Geertjan van Tienhoven
University of Amsterdam
CancerInternal medicineRadiologySurgeryOncologyRandomized controlled trialFiducial markerSentinel nodeClinical endpointAxillaChemotherapyMastectomyChemoradiotherapyMEDLINEHyperthermiaPancreatic cancerToxicityNuclear medicineRadiation therapyBreast cancerClinical trialMedicine
Publications 126
#1D.J. den Boer (UvA: University of Amsterdam)H-Index: 1
#2Johannes K. Veldman (UvA: University of Amsterdam)
Last. Zdenko van Kesteren (UvA: University of Amsterdam)H-Index: 4
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BACKGROUND In radiotherapy, respiratory-induced tumor motion is typically measured using a single four-dimensional computed tomography acquisition (4DCT). Irregular breathing leads to inaccurate motion estimates, potentially resulting in undertreatment of the tumor and unnecessary dose to healthy tissue. The aim of the research was to determine if a daily pre-treatment 4DMRI-strategy led to a significantly improved motion estimate compared to single planning 4DMRI (with or without outlier reject...
#1Conny VrielingH-Index: 13
#2Samson Y. Assele (Katholieke Universiteit Leuven)
Last. Harry Bartelink (NKI-AVL: Netherlands Cancer Institute)H-Index: 91
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Abstract null null Purpose null To analyse the prognostic impact of isolated local recurrence (ILR) on long-term outcome for early-breast cancer patients treated with breast-conserving therapy. null null null Material and methods null The data of the EORTC 22881–10882 ‘boost-no boost’ and 22922–10925 ‘IM-MS’ trials were used to analyse the prevalence and outcome following ILR. A multistate model described the impact of intermediate events on long-term outcomes, taking into account various progno...
#1Philip Poortmans (University of Antwerp)H-Index: 56
#2Henk Struikmans (LEI: Leiden University)H-Index: 35
Last. Ernest VonkH-Index: 9
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BACKGROUND Uncertainty about the benefit/risk ratio of regional lymph node irradiation led to varying clinical protocols. We investigated long-term late side effects after internal mammary and medial supraclavicular (IM-MS) lymph node irradiation to improve shared decision-making. METHODS The multicentre EORTC trial (, NCT00002851) randomized stage I-III breast cancer patients with involved axillary nodes and/or a medially located primary tumor. We analyzed late side effects, b...
1 CitationsSource
#1Quisette P Janssen (EUR: Erasmus University Rotterdam)H-Index: 3
#2Jacob L. van Dam (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Alice C. Wei (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 5
view all 14 authors...
#1Quisette P Janssen (EUR: Erasmus University Rotterdam)H-Index: 3
#2Jacob L. van Dam (EUR: Erasmus University Rotterdam)H-Index: 3
Last. Alice C. Wei (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 5
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BACKGROUND The added value of radiotherapy following neoadjuvant FOLFIRINOX chemotherapy in patients with resectable or borderline resectable pancreatic cancer ((B)RPC) is unclear. The objective of this meta-analysis was to compare outcomes of patients who received neoadjuvant FOLFIRINOX alone or combined with radiotherapy. METHODS A systematic literature search was performed in Embase, Medline (ovidSP), Web of Science, Scopus, Cochrane, and Google Scholar. The primary endpoint was pooled median...
1 CitationsSource
4016Background: Preoperative chemoradiotherapy (CRT) may improve overall survival in resectable pancreatic cancer (RPC) and borderline resectable pancreatic cancer (BRPC). Long term results are pre...
5 CitationsSource
#1Stijn van Roessel (UvA: University of Amsterdam)H-Index: 7
#2Eline C. Soer (UvA: University of Amsterdam)H-Index: 5
Last. Marc G. Besselink (UvA: University of Amsterdam)H-Index: 84
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Abstract Introduction Whereas neoadjuvant chemo(radio)therapy is increasingly used in pancreatic cancer, it is currently not recommended for other periampullary (non-pancreatic) cancers. This has important implications for the relevance of the preoperative diagnosis for pancreatoduodenectomy. This retrospective multicentre cohort study aimed to determine the frequency of clinically relevant misdiagnoses in patients undergoing pancreatoduodenectomy for pancreatic or other periampullary cancer. Me...
4 CitationsSource
#2Eva VersteijneH-Index: 11
Last. B. Groot KoerkampH-Index: 2
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#3Stijn van Roessel (UvA: University of Amsterdam)H-Index: 7
#5Olca Basturk (MSK: Memorial Sloan Kettering Cancer Center)H-Index: 48
Last. Noriyoshi Fukushima (Jichi Medical University)H-Index: 51
view all 32 authors...
Histopathologically scoring the response of pancreatic ductal adenocarcinoma (PDAC) to neoadjuvant treatment can guide the selection of adjuvant therapy and improve prognostic stratification. However, several tumor response scoring (TRS) systems exist, and consensus is lacking as to which system represents best practice. An international consensus meeting on TRS took place in November 2019 in Amsterdam, The Netherlands. Here, we provide an overview of the outcomes and consensus statements that o...
6 CitationsSource