Jeffrey B. Geske
Mayo Clinic
Interquartile rangeInternal medicineSurgeryCardiologyHemodynamicsHazard ratioSudden cardiac deathSeptal myectomyVentricular outflow tractSeptic shockHeart failureCoronary artery diseaseSepsisCardiomyopathyAtrial fibrillationHypertrophic cardiomyopathyVentricular outflow tract obstructionPopulationIn patientDiastoleMedicineEjection fraction
195Publications
27H-index
2,120Citations
Publications 201
Newest
#1Jeffrey B. Geske (Mayo Clinic)H-Index: 27
#2Steve R. Ommen (Mayo Clinic)H-Index: 80
Last. Bernard J. Gersh (Mayo Clinic)H-Index: 167
view all 3 authors...
Abstract Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiomyopathy, manifesting as left ventricular hypertrophy in the absence of a secondary cause. The genetic underpinnings of HCM arise largely from mutations of sarcomeric proteins; however, the specific underlying mutation often remains undetermined. Patient presentation is phenotypically diverse, ranging from asymptomatic to heart failure or sudden cardiac death. Left ventricular hypertrophy and abnormal ventricular confi...
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#1Anita Nguyen (Mayo Clinic)H-Index: 10
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 132
Last. Steve R. Ommen (Mayo Clinic)H-Index: 80
view all 6 authors...
Apical hypertrophic cardiomyopathy (ApHCM) is a variant of hypertrophic cardiomyopathy. Extensive ApHCM may reduce left ventricular (LV) end-diastolic volume and contribute to diastolic dysfunction, angina, and ventricular arrhythmias. For severely symptomatic patients, we have performed apical
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#1Erica D. Bonura (Mayo Clinic)H-Index: 1
#2Mahmoud A. Abdelsalam (Mayo Clinic)H-Index: 1
Last. Jeffrey B. Geske (Mayo Clinic)H-Index: 27
view all 7 authors...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, with varied timing of phenotypic and clinical presentation. Literature describing cardiac magnetic resonance (CMR) imaging and late gadolinium enhancement (LGE) in young patients with HCM is limited. This study included
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#1Anita Nguyen (Mayo Clinic)H-Index: 10
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 132
Last. Steve R. Ommen (Mayo Clinic)H-Index: 80
view all 7 authors...
OBJECTIVES: Patients with hypertrophic obstructive cardiomyopathy and basal septal thickness 21 mm, n = 505), were performed with the Kruskal-Wallis and the Pearson χ2 tests and semiparametric analysis of covariance. RESULTS: Median group ages were 57, 57 and 54 years (P = 0.007); men comprised 50.4%, 56.7% and 62.0%, respectively (P = 0.003). Intrinsic MV disease was present in 5.9%, 5.2% and 4.6%, respectively (P = 0.80). All patients underwent transaortic septal myectomy. Additional mitral pr...
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#1Saraschandra Vallabhajosyula (Mayo Clinic)H-Index: 25
#2Ankit Sakhuja (Mayo Clinic)H-Index: 19
Last. Jacob C. Jentzer (Mayo Clinic)H-Index: 25
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BACKGROUND: To evaluate the clinical features and outcomes of acute cardiorenal syndrome type-5 in patients with severe sepsis and septic shock. METHODS: Historical cohort study of all adult patients with severe sepsis and septic shock admitted to the intensive care units (ICU) at Mayo Clinic Rochester from January 1, 2007 through December 31, 2014. Patients with prior renal or cardiac dysfunction were excluded. Patients were divided into groups with and without cardiorenal syndrome type-5. Acut...
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#1Ratnasari Padang (Mayo Clinic)H-Index: 14
#2Bernard J. Gersh (Mayo Clinic)H-Index: 167
Last. Jeffrey B. Geske (Mayo Clinic)H-Index: 27
view all 4 authors...
Background The association between bicuspid aortic valve (BAV) and hypertrophic cardiomyopathy (HCM) has been reported but its true prevalence is unknown. This study investigated the prevalence and clinical impact of coexistent BAV in a large referral HCM population. Methods Retrospective analysis of 3765 echocardiograms between 2004 and 2014 in 2640 consecutive patients with HCM was performed to assess for BAV. Patients with coexistent conditions were studied. Results Twenty-three patients (0.9...
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#1Carolyn M. Larsen (Mayo Clinic)H-Index: 6
#2Caroline A. Ball (Mayo Clinic)H-Index: 3
Last. Jeffrey B. Geske (Mayo Clinic)H-Index: 27
view all 10 authors...
The objective of this study was to evaluate the relation between body mass index (BMI), exercise capacity, and symptoms in patients with hypertrophic cardiomyopathy (HC) and to utilize results of cardiopulmonary exercise tests (CPX) and transthoracic echocardiograms to understand the mechanism(s) of reduced exercise capacity across body mass index groups. Over a 6-year period, 510 consecutive patients with HC seen at a tertiary referral center underwent (CPX) and a transthoracic echocardiogram. ...
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#10Hongfang LiuH-Index: 1
#1Chadi Ayoub (Mayo Clinic)H-Index: 6
#2Jeffrey B. Geske (Mayo Clinic)H-Index: 27
Last. Patricia A. Pellikka (Mayo Clinic)H-Index: 103
view all 6 authors...
Guidelines recommend exercise stress echocardiogram (ESE) for patients with hypertrophic cardiomyopathy (HC) if a 50 mm Hg gradient is not present at rest or provoked with Valsalva or amyl nitrite, to direct medical and surgical management. However, no study has directly compared all 3 methods. We sought to evaluate efficacy and degree of provocation of left ventricular outflow gradients by ESE, and compare with Valsalva and amyl nitrite. In patients with HC between 2002 and 2015, resting echoca...
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#1Jeffrey B. Geske (Mayo Clinic)H-Index: 27
#2Kevin C. Ong (Mayo Clinic)H-Index: 5
Last. Steve R. Ommen (Mayo Clinic)H-Index: 80
view all 12 authors...
Abstract Sex differences in hypertrophic cardiomyopathy (HCM) remain unclear. We sought to characterize sex differences in a large HCM referral centre population. Three thousand six hundred and seventy-three adult patients with HCM underwent evaluation between January 1975 and September 2012 with 1661 (45.2%) female. Kaplan-Meier survival curves were assessed via log-rank test. Cox proportional hazard regression analyses evaluated the relation of sex with survival. At index visit, women were old...
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