Jeffrey B. Geske
Mayo Clinic
Interquartile rangeInternal medicineSurgeryCardiologyHemodynamicsHazard ratioSudden cardiac deathSeptal myectomyVentricular outflow tractSeptic shockHeart failureCoronary artery diseaseSepsisCardiomyopathyAtrial fibrillationHypertrophic cardiomyopathyVentricular outflow tract obstructionPopulationIn patientDiastoleMedicineEjection fraction
195Publications
25H-index
2,120Citations
Publications 196
Newest
#1Hao Cui (Mayo Clinic)H-Index: 4
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 131
Last. Steve R. Ommen (Mayo Clinic)H-Index: 78
view all 7 authors...
Objective null To determine the characteristics of longitudinal strain and its impact on outcomes in patients with obstructive HCM undergoing septal myectomy. null null null Methods null We reviewed patients with obstructive HCM who underwent septal myectomy at our Clinic from 2007 to 2016. Those who had strain echocardiography within 6 months before isolated myectomy were analyzed. null null null Results null The median age of the 857 patients studied was 55 (44, 63) years, and 451 (52.6%) were...
1 CitationsSource
#1Fatima M. Ezzeddine (Mayo Clinic)H-Index: 1
#2John R. Giudicessi (Mayo Clinic)H-Index: 22
Last. Jeffrey B. Geske (Mayo Clinic)H-Index: 25
view all 6 authors...
Abstract Chronic use of hydroxychloroquine can result in cardiomyopathy and conduction disturbances. Here, we describe a case of hydroxychloroquine cardiotoxicity in a patient with heart failure wi...
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#1Hao Cui (Mayo Clinic)H-Index: 4
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 131
Last. Steve R. Ommen (Mayo Clinic)H-Index: 78
view all 8 authors...
Abstract null null Objective null To determine the impact of sleep-disordered breathing (SDB) on survival in patients with hypertrophic cardiomyopathy (HCM) following septal myectomy. null null null Patients and Methods null Patients with obstructive HCM undergoing septal myectomy from 2007 to 2016 were reviewed. Those who had an overnight oximetry test within 6 months before myectomy were included in analysis. Oxygen desaturation index was examined continuously and also categorically (SDB [>5/h...
1 CitationsSource
#1Anita Nguyen (Mayo Clinic)H-Index: 10
#2Hartzell V. Schaff (Mayo Clinic)H-Index: 131
Last. Rick A. Nishimura (Mayo Clinic)H-Index: 128
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BACKGROUND Surgical myectomy eliminates symptoms in most patients with obstructive hypertrophic cardiomyopathy, but dyspnea and/or angina can recur in some. This study investigated clinical features associated with a lack of clinical improvement postoperatively. METHODS Between March 2007 and December 2012, 963 patients underwent transaortic septal myectomy at our clinic. Six hundred one patients received standardized follow-up questionnaires, which were answered by 409 (68.1%). We compared clin...
2 CitationsSource
#1Zi Ye (Mayo Clinic)
#2Mark M. Smith (Mayo Clinic)H-Index: 7
Last. Hector I. Michelena (Mayo Clinic)H-Index: 47
view all 9 authors...
Objectives null Cleft-like indentations (CLIs) of the mitral valve (MV) are best assessed with three-dimensional (3D) transesophageal echocardiography (TEE). The present study examined the prevalence, characteristics, and surgical effect of MV CLIs in patients with hypertrophic cardiomyopathy (HCM). null null null Design null Prospective, observational, case-control study. null null null Setting null Tertiary medical center. null null null Participants null The study comprised 90 patients with H...
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#1Juliano Lentz Carvalho (Mayo Clinic)H-Index: 3
#2Elena Ashikhmina (Mayo Clinic)H-Index: 8
Last. Hartzell V. Schaff (Mayo Clinic)H-Index: 131
view all 7 authors...
OBJECTIVES It is not uncommon to observe some discrepancy in hemodynamic values characterizing left ventricular outflow tract (LVOT) obstruction preoperatively and in the operating room in patients with hypertrophic obstructive cardiomyopathy. Interpretation of this discrepancy can be challenging. To clarify the extent of the discrepancy, the authors compared hemodynamic variables in patients undergoing septal myectomy at the time of preoperative and intraoperative evaluation. DESIGN Retrospecti...
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#1Milind Y. Desai (Cleveland Clinic)H-Index: 66
#2Kathy Wolski (Cleveland Clinic)H-Index: 58
Last. Steven E. Nissen (Cleveland Clinic)H-Index: 104
view all 14 authors...
BACKGROUND Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder which frequently leads to symptoms such as dyspnea and exercise intolerance, often due to severe dynamic left ventricular outflow tract obstruction (LVOTO). Current guideline-recommended pharmacotherapies have variable therapeutic responses to relieve LVOTO. In recent phase 2 and 3 clinical trials for symptomatic obstructive HCM (oHCM), mavacamten, a small molecule inhibitor of β-cardiac myosin has been shown to improv...
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#1Konstantinos C. Siontis (Mayo Clinic)H-Index: 23
#2Huzefa Bhopalwala (Mayo Clinic)H-Index: 1
Last. Adelaide M. Arruda-Olson (Mayo Clinic)H-Index: 18
view all 11 authors...
Abstract Background The follow-up of implantable cardioverter-defibrillators (ICDs) generates large amounts of valuable structured and unstructured data embedded in device interrogation reports. Objective We aimed to build a natural language processing (NLP) model for automated capture of ICD-recorded events from device interrogation reports using a single-center cohort of patients with hypertrophic cardiomyopathy (HCM). Methods A total of 687 ICD interrogation reports from 247 HCM patients were...
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