Giovanni Marchegiani
University of Verona
Internal medicineRadiologySurgeryPathologyOncologyRetrospective cohort studyIntraductal papillary mucinous neoplasmCarcinomaPancreatectomyPancreasPancreaticoduodenectomyPancreatic ductPancreatic cancerPancreatic fistulaDistal pancreatectomyPancreatic surgeryIncidence (epidemiology)General surgeryMedicineGastroenterology
292Publications
29H-index
5,343Citations
Publications 287
Newest
#1Andrea Lisotti (UNIBO: University of Bologna)H-Index: 17
#2Bertrand NapoleonH-Index: 28
Last. Giovanni MarchegianiH-Index: 29
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Abstract null null Background and aims null Pancreatic cystic neoplasms (PCNs) carry a not-negligible malignancy risk. Along with main duct dilation, presence of enhanced mural nodules represents a significant risk factor for malignancy. Several articles assessed the role of contrast-enhanced endoscopic ultrasound (CE-EUS) for the identification of malignant features in mural nodules. We evaluate the pooled diagnostic performance of CE-EUS for the identification of high-grade dysplasia or invasi...
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#1Tommaso GiulianiH-Index: 5
Last. Claudio BassiH-Index: 3
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#1Pascal Probst (Heidelberg University)H-Index: 22
#2Felix J Hüttner (Heidelberg University)H-Index: 16
Last. Marco Del Chiaro (Anschutz Medical Campus)H-Index: 31
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BACKGROUND Pancreatic surgery is associated with considerable morbidity and, consequently, offers a large and complex field for research. To prioritize relevant future scientific projects, it is of utmost importance to identify existing evidence and uncover research gaps. Thus, the aim of this project was to create a systematic and living Evidence Map of Pancreatic Surgery. METHODS PubMed, the Cochrane Central Register of Controlled Trials, and Web of Science were systematically searched for all...
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#1Giovanni Marchegiani (University of Verona)H-Index: 29
#2Claudio Bassi (University of Verona)H-Index: 110
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#1Rita T. LawlorH-Index: 31
#2Paola MattioloH-Index: 3
Last. Roberto SalviaH-Index: 52
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Tumor mutational burden (TMB) is a numeric index that expresses the number of mutations per megabase (muts/Mb) harbored by tumor cells in a neoplasm. TMB can be determined using different approaches based on next-generation sequencing. In the case of high values, it indicates a potential response to immunotherapy. In this systematic review, we assessed the potential predictive role of high-TMB in pancreatic ductal adenocarcinoma (PDAC), as well as the histo-molecular features of high-TMB PDAC. H...
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#1N. Surci (Medical University of Vienna)
Last. Claudio BassiH-Index: 110
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Abstract null null Background null Incidental discovery of pancreatic cystic neoplasms (PCLs) is a common and steadily increasing occurrence. The aim of this study was to investigate a cohort of patients presenting with incidentally detected PCLs which were not included in a surveillance protocol, and to compare their risk of malignant evolution with that of systematically surveilled lesions. null null null Materials and methods null A population of PCLs which did not receive surveillance over a...
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#1Giovanni Marchegiani (University of Verona)H-Index: 29
#2Stefano Andrianello (University of Verona)H-Index: 16
Last. Roberto Salvia (University of Verona)H-Index: 52
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BACKGROUND Despite the low malignant potential of pancreatic mucinous cystic neoplasms (MCNs), surgery is still performed. The aim of this pragmatic study was to assess the outcome of surgery and surveillance for patients presenting with a presumed MCN at the first evaluation. METHODS Data for patients with a presumed MCN observed from 2000 to 2016 at the Verona Pancreas Institute and San Raffaele Hospital were extracted from prospective databases. The endpoints were risk of malignancy at pathol...
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#1Giovanni Marchegiani (University of Verona)H-Index: 29
#2Tommaso Pollini (University of Verona)H-Index: 8
Last. Roberto Salvia (University of Verona)H-Index: 52
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Importance The progression of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas to malignant disease is still poorly understood. Observational and surgical series have failed to provide comprehensive information. Objective To identify dynamic variables associated with the development of malignant neoplasms by combining pathological features with data from preoperative repeated observations. Design, Setting, and Participants The Crossover Observational Multicentric Study included a...
1 CitationsSource
#1A. Balduzzi (University of Verona)H-Index: 4
#2Giovanni Marchegiani (University of Verona)H-Index: 29
Last. Roberto Salvia (University of Verona)H-Index: 52
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Abstract Background The vast majority of presumed branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas are referred to a surveillance program due to the relatively low risk of malignancy. We aim to evaluate all available data from observational studies focused on the risks of BD-IPMN progression and malignancy to provide vital insights into its management in clinical practice. Methods A comprehensive search was conducted at PubMed, Cochrane, Web of Science and Embase f...
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#2V. M. KopchakH-Index: 1
Last. Kostiantyn KopchakH-Index: 2
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BACKGROUND To develop a prevention system that allows to reduce frequency of pancreatic fistula and severe postoperative complications after pancreaticoduodenectomy. METHODS In our department results of 143 pancreatic head resections were analyzed in the period from January 2017 to December 2019. In the main group we proposed pancreatic fistula prevention system and assessment of sarcopenia that were applied in 56 patients during a year (from November 2018 to December 2019). In patients with hig...
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