Culadeeban Ratneswaran
Guy's and St Thomas' NHS Foundation Trust
AirwaySleep in non-human animalsStructured interviewControl of respirationSupine positionInternal medicineBreathingPublic healthDemographyCardiologyPhysical therapyParasternal lineStimulationObstructive sleep apneaDilatorSmoking cessationPolysomnographyAirway obstructionEpworth Sleepiness ScaleContinuous positive airway pressureBody mass indexObese subjectsAnesthesiaRespiratory systemMedicineCohortBlood pressure
37Publications
6H-index
129Citations
Publications 31
Newest
#1Culadeeban Ratneswaran (Guy's and St Thomas' NHS Foundation Trust)H-Index: 6
#2Ahmad Guni ('KCL': King's College London)H-Index: 2
Last. Esther I. Schwarz (Guy's and St Thomas' NHS Foundation Trust)H-Index: 13
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Introduction Electrical stimulation of the upper airway dilator muscles is an emerging treatment for obstructive sleep apnea (OSA). Hypoglossal nerve stimulation (HNS) has recently been approved as treatment alternative to continuous positive airway pressure (CPAP) for selected patients with moderate to severe OSA, while transcutaneous electrical stimulation (TES) of the upper airway is being investigated as non-invasive alternative. Methods A systematic review and meta-analysis (CRD42017074674)...
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1 CitationsSource
#2Joerg Steier ('KCL': King's College London)H-Index: 25
Last. Teck K Khong (St George's, University of London)H-Index: 8
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Introduction In contrast to tobacco smoking, electronic cigarette (“vaping”) advertisement had been approved in the United Kingdom (UK) in January 2013. Currently, there are an estimated 3.2 million UK e-cigarette users. The impact of e-cigarette advertisement on tobacco use has not been studied in detail. We hypothesised that e-cigarette advertisement impacts on conventional smoking behaviour.
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#1Baiting He (Guangzhou Medical University)H-Index: 6
#2Miral Al-Sherif ('KCL': King's College London)H-Index: 2
Last. Joerg SteierH-Index: 25
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Obstructive sleep apnoea (OSA) is a global health problem of increasing prevalence. Effective treatments are available with continuous positive airway pressure (CPAP) therapy and mandibular advancement devices (MAD). However, there is limited long-term adherence to therapy, as CPAP and MAD require permanent usage to avoid recurrence of the symptoms and adverse ill health. Alternative treatments would aid in the treatment cascade to manage OSA effectively whenever standard therapy has been triall...
7 CitationsSource
#1Miral Al-Sherif ('KCL': King's College London)H-Index: 2
#2Baiting He ('KCL': King's College London)H-Index: 6
Last. Joerg SteierH-Index: 25
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#1Culadeeban Ratneswaran (Guy's and St Thomas' NHS Foundation Trust)H-Index: 6
#2Martino F. Pengo (Guy's and St Thomas' NHS Foundation Trust)H-Index: 17
Last. Joerg Steier (Guy's and St Thomas' NHS Foundation Trust)H-Index: 25
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AbstractObjectives: Continuous positive airway pressure (CPAP) improves upper airway obstruction in patients with obstructive sleep apnoea (OSA), who often are overweight-obese. Although it is thought that CPAP improves long-term blood pressure control (BP), the impact of acute and short-term CPAP use on the cardiovascular system in obese patients has not been described in detail.Methods: Obese patients (body mass index, BMI > 25 kg/m2) with OSA were studied awake, supine during incremental CPAP...
6 CitationsSource
#1Culadeeban Ratneswaran (Guy's and St Thomas' NHS Foundation Trust)H-Index: 6
#2Manpreet K. Sagoo ('KCL': King's College London)H-Index: 2
Last. Joerg SteierH-Index: 25
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Sleep medicine remains an exciting and fast-evolving field of medicine with insomnia, hypersomnia, parasomnia, sleep-disordered breathing and circadian rhythm disorders affecting significant proportions of the population. This update provides a selected overview about recent publications in the field.
2 CitationsSource
#1Culadeeban Ratneswaran (Guy's and St Thomas' NHS Foundation Trust)H-Index: 6
#2Patrick B. Murphy ('KCL': King's College London)H-Index: 20
Last. Joerg Steier ('KCL': King's College London)H-Index: 25
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Obesity causes an increased load on the respiratory muscle pump that impacts on the work of breathing and requires high levels of neural respiratory drive. Elevated intra-abdominal pressures in obesity impose a preload on the diaphragm during inspiration, particularly in the supine posture. These forces contribute to a reduced transpulmonary pressure gradient in the thoracic compartment and affect operational lung volumes. Morbidly obese subjects breathe at low lung volumes, close to the residua...
1 CitationsSource
#1Kate ReedH-Index: 4
#2Martino F. PengoH-Index: 17
Last. Joerg SteierH-Index: 25
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Introduction Transcutaneous electrical stimulation (TES) provides neuromuscular tone to the pharyngeal dilator muscles of the upper airway (UA) while asleep, but feasibility of this method to treat obstructive sleep apnoea (OSA) throughout the whole night has not been tested. Patients and methods We conducted a phase two double-blind, sham-controlled, randomised controlled trial using TES of the UA muscles in 36 patients with confirmed OSA to assess patients’ device acceptance and the side effec...
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#1Culadeeban Ratneswaran ('KCL': King's College London)H-Index: 6
#2Ben Chisnall ('KCL': King's College London)H-Index: 4
Last. Joerg Steier ('KCL': King's College London)H-Index: 25
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Objectives We compared 2 sociocultural cohorts with different duration of exposure to graphic health warning labels (GHWL), to investigate a possible desensitisation to their use. We further studied how a differing awareness and emotional impact of smoking-associated risks could be used to prevent this. Setting Structured interviews of patients from the general respiratory department were undertaken between 2012 and 2013 in 2 tertiary hospitals in Singapore and London. Participants 266 participa...
12 CitationsSource