Maria Pellise
University of Barcelona
Internal medicineRadiologySurgeryPathologyOdds ratioHumanitiesProspective cohort studyLynch syndromeAdenomaColonoscopyEndoscopyEndoscopic mucosal resectionPopulationGynecologyIn patientIncidence (epidemiology)Colorectal cancerGeneral surgeryMedicineGastroenterology
Publications 361
#1O OrtizH-Index: 3
#2Douglas K. Rex (IU: Indiana University)H-Index: 116
Last. Maria PelliseH-Index: 47
view all 25 authors...
Background. Delayed bleeding is a common adverse event following endoscopic mucosal resection (EMR) of large colorectal polyps. Prophylactic clip closure of the mucosal defect after EMR of ≥20 mm non-pedunculated polyps reduces the incidence of severe delayed bleeding, especially in proximal polyps. Aim: Evaluate factors associated with complete prophylactic clip closure of the mucosal defect after EMR of large polyps. Methods: This is a post-hoc analysis of the CLIP STUDY (NCT01936948). All pat...
Background: The major limitation of piecemeal endoscopic mucosal resection (EMR) is the inaccurate histological assessment of the resected specimen, especially in cases of submucosal invasion. Objective: To classify non-pedunculated lesions ≥20 mm based on endoscopic morphological features, in order to identify those that present intramucosal neoplasia (includes low-grade neoplasia and high-grade neoplasia) and are suitable for piecemeal EMR. Design: A post-hoc analysis from an observational pro...
#1Sabela Carballal (University of Barcelona)H-Index: 14
#2Ariadna Sánchez (University of Barcelona)H-Index: 10
Last. Francesc Balaguer (University of Barcelona)H-Index: 46
view all 18 authors...
Background and study aims: current guidelines recommend genetic counseling and intensive colonoscopy surveillance for patients with ≥10 colorectal adenomas based on scarce data. We investigated the prevalence of this condition in a FIT (fecal immunochemical test)-based colorectal (CRC) screening program and the incidence of metachronous lesions during follow-up. null Patients and methods: we retrospectively included all FIT-positive participants with ≥10 adenomas at index colonoscopy between 201...
Objective Large (≥20 mm) sessile serrated lesions (L-SSL) are premalignant lesions that require endoscopic removal. Endoscopic mucosal resection (EMR) is the existing standard of care but carries some risk of adverse events including clinically significant post-EMR bleeding and deep mural injury (DMI). The respective risk-effectiveness ratio of piecemeal cold snare polypectomy (p-CSP) in L-SSL management is not fully known. Design Consecutive patients referred for L-SSL management were treated b...
#1Carlos Guarner-Argente (Autonomous University of Barcelona)H-Index: 14
#2Hiroaki IkematsuH-Index: 28
Last. Santiago SotoH-Index: 5
view all 36 authors...
Abstract null null Background and study aims null Data from Japanese series show that surface morphology of laterally spreading tumors (LST) in the colon identifies lesions with different incidence and pattern of submucosal invasion. Such data from western countries are scarce. We compared clinical and histological features of LST in a western country and an eastern country, with special interest on mucosal invasiveness of LST, and investigated the effect of clinical factors on invasiveness in b...
#1Yuma Wada (University of Tokushima)H-Index: 5
#2Mitsuo Shimada (University of Tokushima)H-Index: 91
Last. Ajay Goel (Beckman Research Institute)H-Index: 93
view all 14 authors...
ABSTRACT Background & Aims We recently reported use of tissue-based transcriptomic biomarkers (miRNA or mRNA) for identification of lymph node metastasis (LNM) in patients with invasive submucosal colorectal cancers (T1 CRC). In this study, we translated our tissue-based biomarkers into a blood-based liquid biopsy assay for noninvasive detection of LNM in patients with high-risk T1 CRC. Methods We analyzed 330 specimens from patients with high-risk T1 CRC, which included 188 serum samples from t...
#1Anthony Whitfield (USYD: University of Sydney)H-Index: 1
#2Nicholas G. Burgess (USYD: University of Sydney)H-Index: 19
Last. Karen Byth (Westmead Hospital)H-Index: 69
view all 11 authors...
Objective null Endoscopic mucosal resection (EMR) in the colon has been widely adopted, but there is limited data on the histopathological effects of the differing electrosurgical currents (ESCs) used. We used an in vivo porcine model to compare the tissue effects of ESCs for snare resection and adjuvant margin ablation techniques. null Design null Standardised EMR was performed by a single endoscopist in 12 pigs. Two intersecting 15 mm snare resections were performed. Resections were randomised...
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