Hanns-Christian Gunga
Humboldt University of Berlin
SpaceflightCircadian rhythmEndocrinologyBiomedical engineeringCore (anatomy)PsychologyCardiologyPhysical exerciseChemistryDeconditioningBed restHeart rateErythropoietinMetabolic syndromeBlood volumeWeightlessnessMedicineEffects of high altitude on humansBlood pressureBiology
97Publications
20H-index
1,243Citations
Publications 113
Newest
#1Lawrence Rice (Cornell University)H-Index: 33
#2Hanns-Christian Gunga (Humboldt University of Berlin)H-Index: 20
So is science - just a few years ago one of us (1) co-authors an editorial on a phenomenon of the destruction of young red blood cells outside the bone marrow in the circulating blood, named neocytolysis by Alfrey et al. (2, 3). Now, a new study from high altitude published by Mairbaurl et al. (4) in this journal seems to shed a new light on this topic and raises concerns whether this phenomenon really exists.
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#1Stefan MendtH-Index: 5
#2Katharina BraunsH-Index: 3
Last. Alexander C. Stahn (Humboldt University of Berlin)
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#1Marc Jörres (Humboldt University of Berlin)
#2Hanns-Christian Gunga (Humboldt University of Berlin)H-Index: 20
Last. Mathias Steinach (Humboldt University of Berlin)H-Index: 9
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Background: Long endurance exercises like ultramarathons are known to elicit various metabolic and physiological changes in the human body. However, little is known about very long duration exercise at low intensities regarding healthy human subjects. Aim: The purpose of this study was to evaluate changes in body composition and metabolism in long endurance but low intensity events. Methods: 25 male and 18 female healthy participants (age 34.6 ± 8.8 years; BMI: 22.4 ± 2.0 kg/m²) of the “100 km M...
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#1Katharina Brauns (FU: Free University of Berlin)H-Index: 3
#1Katharina Brauns (FU: Free University of Berlin)
Last. Alexander Stahn (FU: Free University of Berlin)H-Index: 12
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Abstract Physical inactivity across the lifespan is a growing public health concern affecting the cardiovascular, musculoskeletal, and central nervous system. Data on the effects of dietary antioxidants as neuroprotective treatments when physical activity levels are impaired are lacking. In this randomized controlled study twenty young healthy men underwent 60 days of bed rest. Participants were randomly assigned to a treatment group (N=10) receiving a daily antioxidant supplement comprising pol...
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#1Katharina Brauns (Humboldt University of Berlin)H-Index: 3
#2Anika Friedl-Werner (Humboldt University of Berlin)H-Index: 1
Last. Alexander Stahn (Humboldt University of Berlin)H-Index: 12
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Adverse cognitive and behavioral conditions and psychiatric disorders are considered a critical and unmitigated risk during future long-duration space missions (LDSM). Monitoring and mitigating crew health and performance risks during these missions will require tools and technologies that allow to reliably assess cognitive performance capability and mood states. Electroencephalography (EEG) has the potential to meet the technical requirements for the use during LDSM. Weightlessness is associate...
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#1Martina A. MaggioniH-Index: 14
#2Giampiero Merati (University of Insubria)H-Index: 1
Last. Alexander C. Stahn (Humboldt University of Berlin)H-Index: 1
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1 CitationsSource
#1Björn Balcerek (Humboldt University of Berlin)H-Index: 1
#2Mathias Steinach (Humboldt University of Berlin)H-Index: 9
Last. Michael Fähling (Humboldt University of Berlin)H-Index: 22
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Oxygen affinity to haemoglobin is indicated by the p50 value (pO2 at 50% O2Hb) and critically determines cellular oxygen availability. Although high Hb-O2 affinity can cause tissue hypoxia under conditions of well O2 saturated blood, individual differences in p50 are commonly not considered in clinical routine. Here, we investigated the diversity in Hb-O2 affinity in the context of physiological relevance. Oxyhaemoglobin dissociation curves (ODCs) of 60 volunteers (18-40 years, both sexes, eithe...
3 CitationsSource
#1Anika Friedl-Werner (Humboldt University of Berlin)H-Index: 1
#2Katharina Brauns (Humboldt University of Berlin)H-Index: 3
Last. Alexander Stahn (Humboldt University of Berlin)H-Index: 12
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Episodic memory depends decisively on the hippocampus and the parahippocampal gyrus, brain structures that are also prone to exercise-induced neuroplasticity and cognitive improvement. We conducted a randomized controlled trial to investigate the effects of a high-intensity exercise program in twenty-two men resting in bed for 60 days on episodic memory and its neuronal basis. All participants were exposed to 60 days of uninterrupted bed rest. Eleven participants were additionally assigned to a ...
4 CitationsSource
#1Martina A. Maggioni (Humboldt University of Berlin)H-Index: 14
#2Lea C. Rundfeldt (Humboldt University of Berlin)H-Index: 2
Last. Mathias Steinach (Humboldt University of Berlin)H-Index: 9
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Cardiac autonomic modulation of heart rate, assessed by heart rate variability (HRV), is commonly used to monitor training status. HRV is usually measured in athletes after awakening in the morning in the supine position. Whether recording during standing reveals additional information compared to supine remains unclear. We aimed to evaluate the association between short-duration HRV, assessed both in the supine and standing position, and a low-intensity long-duration performance (walking ultram...
1 CitationsSource