Marissa Westerfield
University of California, San Diego
Developmental psychologyStimulus (physiology)Eye movementArtificial intelligencePsychologyNeuroscienceCognitionVisual perceptionPattern recognitionCognitive psychologyElectrophysiologyAutismScalpAutism spectrum disorderGazeSpeech recognitionComputer scienceBrain mappingIndependent component analysisElectroencephalographyAudiologyEvent-related potential
36Publications
20H-index
5,404Citations
Publications 32
Newest
#1Brandon Keehn (Purdue University)H-Index: 24
#2Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
Last. Jeanne Townsend (UCSD: University of California, San Diego)H-Index: 42
view all 3 authors...
This study investigates how task-irrelevant auditory information is processed in children with autism spectrum disorder (ASD). Eighteen children with ASD and 19 age- and IQ-matched typically developing (TD) children were presented with semantically-congruent and incongruent picture-sound pairs, and in separate tasks were instructed to attend to only visual or both audio-visual sensory channels. Preliminary results showed that when required to attend to both modalities, both groups were equally s...
2 CitationsSource
#1Joaquin Rapela (UCSD: University of California, San Diego)H-Index: 6
#2Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
Last. Jeanne Townsend (UCSD: University of California, San Diego)H-Index: 42
view all 3 authors...
This letter makes scientific and methodological contributions. Scientifically, it demonstrates a new and behaviorally relevant effect of temporal expectation on the phase coherence of the electroencephalogram (EEG). Methodologically, it introduces novel methods to characterize EEG recordings at the single-trial level. Expecting events in time can lead to more efficient behavior. A remarkable finding in the study of temporal expectation is the foreperiod effect on reaction time, that is, the infl...
1 CitationsSource
#1Leanne ChukoskieH-Index: 7
#2Marissa WesterfieldH-Index: 20
Last. Jeanne TownsendH-Index: 42
view all 3 authors...
: In addition to the social, communicative and behavioral symptoms that define the disorder, individuals with ASD have difficulty re-orienting attention quickly and accurately. Similarly, fast re-orienting saccadic eye movements are also inaccurate and more variable in both endpoint and timing. Atypical gaze and attention are among the earliest symptoms observed in ASD. Disruption of these foundation skills critically affects the development of higher level cognitive and social behavior. We prop...
14 CitationsSource
#1Brandon Keehn (Purdue University)H-Index: 24
#2Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
Last. Jeanne Townsend (UCSD: University of California, San Diego)H-Index: 42
view all 4 authors...
Abstract Background Autism spectrum disorder (ASD) is associated with deficits in adaptively orienting attention to behaviorally relevant information. Neural oscillatory activity plays a key role in brain function and provides a high-resolution temporal marker of attention dynamics. Alpha-band (8–12 Hz) activity is associated with both selecting task-relevant stimuli and filtering task-irrelevant information. Methods The present study used electroencephalography to examine alpha-band oscillatory...
17 CitationsSource
#1Robert K. NaviauxH-Index: 46
#2Brooke Curtis (Alliant International University)H-Index: 1
Last. Jeanne Townsend (UCSD: University of California, San Diego)H-Index: 42
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Objective No drug is yet approved to treat the core symptoms of autism spectrum disorder (ASD). Low-dose suramin was effective in the maternal immune activation and Fragile X mouse models of ASD. The Suramin Autism Treatment-1 (SAT-1) trial was a double-blind, placebo-controlled, translational pilot study to examine the safety and activity of low-dose suramin in children with ASD. Methods Ten male subjects with ASD, ages 5–14 years, were matched by age, IQ, and autism severity into five pairs, t...
46 CitationsSource
#1Joaquin RapelaH-Index: 6
#2Marissa WesterfieldH-Index: 20
Last. Scott MakeigH-Index: 88
view all 4 authors...
Expecting events in time leads to more efficient behavior. A remarkable early finding in the study of temporal expectancy is the foreperiod effect on reaction times; i.e., the influence or reaction time of the time period between a warning signal and an imperative stimulus to which subjects are instructed to respond as quickly as possible. Recently it has been shown that the phase of oscillatory activity preceding stimulus presentation is related to behavior. Here we connect both of these findin...
1 Citations
#1Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
#2Marla Zinni (UCSD: University of California, San Diego)H-Index: 4
Last. Jeanne Townsend (UCSD: University of California, San Diego)H-Index: 42
view all 4 authors...
We recorded visual event-related brain potentials from 32 adult male participants (16 high-functioning participants diagnosed with autism spectrum disorder (ASD) and 16 control participants, ranging in age from 18 to 53 years) during a three-stimulus oddball paradigm. Target and non-target stimulus probability was varied across three probability conditions, whereas the probability of a third non-target stimulus was held constant in all conditions. P3 amplitude to target stimuli was more sensitiv...
8 CitationsSource
#1Sara Jane Webb (UW: University of Washington)H-Index: 42
#2Raphael A. Bernier (UW: University of Washington)H-Index: 59
Last. Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
view all 11 authors...
The EEG reflects the activation of large populations of neurons that act in synchrony and propagate to the scalp surface. This activity reflects both the brain’s background electrical activity and when the brain is being challenged by a task. Despite strong theoretical and methodological arguments for the use of EEG in understanding the neural correlates of autism, the practice of collecting, processing and evaluating EEG data is complex. Scientists should take into consideration both the nature...
47 CitationsSource
#1Nima Bigdely-Shamlo (UCSD: University of California, San Diego)H-Index: 18
#2Kenneth Kreutz-Delgado (UCSD: University of California, San Diego)H-Index: 35
Last. Scott Makeig (UCSD: University of California, San Diego)H-Index: 88
view all 9 authors...
Data from well-designed EEG experiments should find uses beyond initial reports, even when study authors cannot anticipate how it may contribute to future analyses. Several ontologies have been proposed for describing events in cognitive experiments to make data available for re-use and meta-analysis, but none are widely used. One reason for this is that the tools needed to make use of these ontologies are complex, placing a significant burden on experimenters while not providing any immediate r...
18 CitationsSource
#1Leanne Chukoskie (UCSD: University of California, San Diego)H-Index: 7
#2Ahmad Soomro (UCSD: University of California, San Diego)H-Index: 1
Last. Marissa Westerfield (UCSD: University of California, San Diego)H-Index: 20
view all 4 authors...
Attention and eye movement control are essential for gathering sensory information in our environment however, both attention redirection and eye movement control are atypical in individuals with autism spectrum disorder (ASD). Improvements in the accuracy and timing of attention redirection and saccadic eye movements could have corollary beneficial effects on social engagement. Here, we show pilot data indicating proof of concept for such training in a laboratory environment and review the logi...
5 CitationsSource