Iolanda Francolini
Sapienza University of Rome
Nuclear chemistryAdsorptionNanotechnologyBacterial growthOrganic chemistryChemistryPolymer chemistryMaterials scienceCombinatorial chemistryStaphylococcus epidermidisPolyurethaneChitosanDrug deliveryChemical engineeringAntimicrobialTissue engineeringAntibioticsPolymerBiofilmBiofoulingMedicineAdhesionBiologyMicrobiology
93Publications
24H-index
1,975Citations
Publications 89
Newest
#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Riccardo Sergi (Sapienza University of Rome)
Last. Iolanda Francolini (Sapienza University of Rome)H-Index: 24
view all 7 authors...
Abstract In this study, a new scaffold fabrication method based on the combination of a series of stabilization processes was set up to obtain chitosan scaffolds with improved mechanical properties for regeneration of load-bearing tissues. Specifically, thermally induced phase separation (TIPS) of chitosan solutions was used to obtain an open structure which was then stabilized by freeze-gelation and photo cross-linking. Freeze-gelation combined with freeze-drying permitted to obtain a porous st...
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#1Azzurra Apriceno (Sapienza University of Rome)H-Index: 6
#2Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Bioremediation with immobilized enzymes has several advantages, such as the enhancement of selectivity, activity, and stability of biocatalysts, as well as enzyme reusability. Laccase has proven to be a good candidate for the removal of a wide range of contaminants. In this study, naked or modified MnFe2O4 magnetic nanoparticles (MNPs) were used as supports for the immobilization of laccase from Trametes versicolor. To increase enzyme loading and stability, MNPs were coated with chitosan both af...
1 CitationsSource
In this paper, the application of a temperature modulation to the temperature-resolved FTIR analysis is reported. The advantage offered by the spectroscopic investigation, able to follow the micro-structural and conformational sample modification involved in sample thermal transformation, was merged to that of temperature modulation, related to the possibility to separate the reversing (in-equilibrium within the experimental condition) to the non-reversing (non-equilibrium) processes. The potent...
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Poloxamers are nontoxic, amphiphilic copolymers used in different formulations. Due to its surfactant properties, Poloxamer 338 (P388) is herein proposed as a strategy to avoid biofilm formation often causing recalcitrant catheter-associated urinary tract infections (CAUTI). The aim is to evaluate the ability of P388 coatings to affect the adhesion of Ec5FSL and Ec9FSL Escherichia coli strains on silicone urinary catheters. Attenuated total reflection infrared spectroscopy, atomic force microsco...
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#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Iolanda Francolini (Sapienza University of Rome)H-Index: 24
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Scaffolds are three-dimensional porous structures that must have specific requirements to be applied in tissue engineering. Therefore, the study of factors affecting scaffold performance is of great importance. In this work, the optimal conditions for cross-linking preformed chitosan (CS) scaffolds by the tripolyphosphate polyanion (TPP) were investigated. The effect on scaffold physico-chemical properties of different concentrations of chitosan (1 and 2% w/v) and tripolyphosphate (1 and 2% w/v)...
6 CitationsSource
#1Ilaria Silvestro (Sapienza University of Rome)H-Index: 5
#2Mariangela Lopreiato (Sapienza University of Rome)H-Index: 4
Last. Iolanda Francolini (Sapienza University of Rome)H-Index: 24
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Wound healing is a dynamic process that can be seriously delayed by many factors including infectious complications. The development of dressings with intrinsic wound healing activity and/or releasing bioactive compounds may help with addressing such an issue. In this study, hyaluronic acid (HA) at different percentages (1–35%) was used to modify chitosan (CS) biological and physico-chemical properties in order to obtain 2D-matrices able to promote healing and protect from infection. HA incorpor...
5 CitationsSource
#1Loris PietrelliH-Index: 18
#2Iolanda FrancoliniH-Index: 24
Last. Marco VoccianteH-Index: 16
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13 CitationsSource
#1Iolanda Francolini (Sapienza University of Rome)H-Index: 24
#2Vincenzo Taresco (University of Nottingham)H-Index: 16
Last. Antonella Piozzi (Sapienza University of Rome)H-Index: 23
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Abstract Lipase-immobilized nanomaterials with high activity and stable reusability would have a great impact in different fields. However, developing such materials has proven to be challenging. Herein, polymer (pAcDED)-coated magnetic nanoparticles (MNPs) displaying long alkyl chains, either octyl (C8) or hexadecyl (C16), have been prepared and used for immobilization of Candida rugosa lipase. The aim of the study was to develop magnetic supports able to bind enzyme via interfacial activation ...
7 CitationsSource
#1Iolanda Francolini (Sapienza University of Rome)H-Index: 24
#2Antonella Piozzi (Sapienza University of Rome)H-Index: 23
BACKGROUND: Antioxidants are multifaceted molecules playing a crucial role in several cellular functions. There is by now a well-established knowledge about their involvement in numerous processes associated with aging, including vascular damage, neurodegenerative diseases and cancer. An emerging area of application has been lately identified for these compounds in relation to the recent findings indicating their ability to affect biofilm formation by some microbial pathogens, including Staphylo...
1 CitationsSource
#1Iolanda Francolini (Sapienza University of Rome)H-Index: 24
#2Antonella Piozzi (Sapienza University of Rome)H-Index: 23
The rapid increase in the emergence of antibiotic-resistant bacterial strains combined with a dwindling rate of discovery of novel antibiotic molecules has lately created an alarming issue worldwide [...]
2 CitationsSource