Icro Meattini
University of Florence
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyRandomized controlled trialMedical physicsMetastatic breast cancerChemotherapyMastectomyProstate cancerDuctal carcinomaBreast reconstructionBreast-conserving surgeryWhole Breast IrradiationPartial Breast IrradiationNuclear medicineRadiation therapyBreast cancerMedicine
Publications 286
#1Lorenzo Livi (UniFI: University of Florence)H-Index: 28
#2Giuseppe BarlettaH-Index: 23
Last. L. ColtelliH-Index: 5
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Importance Several studies have evaluated cardioprotective strategies to prevent myocardial dysfunction in patients who are receiving cardiotoxic therapies. However, the optimal approach still represents a controversial issue. Objective To determine whether pharmacological cardioprevention could reduce subclinical heart damage in patients with breast cancer who are being treated with anthracycline-based chemotherapy. Design, Setting, and Participants The SAFE trial was a 4-arm, randomized, phase...
#1Giulio FrancoliniH-Index: 13
#2Mauro LoiH-Index: 13
Last. Isacco Desideri (UniFI: University of Florence)H-Index: 17
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In our institution, a prospective observational trial testing micro-RNA (miRNA) and ARV7 mutational status in metastatic, castration resistant prostate cancer (mCRPC), is currently recruiting (PRIMERA trial, NCT04188275). A pre-planned interim analysis was performed when 50% of the planned accrual was reached. In this report, we explored the predictive value of Circulating Tumor Cell (CTC) detection in mCRPC patients undergoing 1st line therapy. Moreover, ARV7, ARFL, PSMA and PSA expression on C...
#1Orit Kaidar-Person (Sheba Medical Center)H-Index: 6
#2Birgitte Vrou Offersen (Aarhus University Hospital)H-Index: 26
Last. V. Strand (FAU: University of Erlangen-Nuremberg)
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Abstract null null Delineation of target and ‘organ at risk (OAR)’ volumes is a critical part of modern radiation therapy planning, the next essential step after deciding the indication, patient discussion and image acquisition. Adoption of volume-based treatment planning for non-metastatic breast cancer has increased greatly along with the use of improved planning techniques, essential for modern therapy. However, identifying the volumes on a planning CT is no easy task. The current paper is wr...
#1Marco BerniniH-Index: 18
#2S SordiH-Index: 5
Last. Lorenzo OrzalesiH-Index: 18
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Abstract null null Background null Selective pectoralis major muscle (PMM) denervation has been described in retro-pectoral reconstructions to obtain the advantages of the pre-pectoral approach. Present study compared subjective evaluations between retro-pectoral implant based breast reconstructions (IBBRs) with denervation to traditional techniques without denervation. Methods. In 2020, two 2 groups of patients submitted to retro-pectoral IBBR, minimum 12-month follow-up, were compared through ...
#1Laura PizzutiH-Index: 20
#2Maddalena BarbaH-Index: 31
Last. Clara Natoli (University of Chieti-Pescara)H-Index: 32
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In metastatic breast cancer (mBC), the change of human epidermal growth factor receptor 2 (HER2) status between primary and metastatic lesions is widely recognized, however clinical implications are unknown. Our study address the question if relevant differences exist between subjects who preserve the HER2 status and those who gain the HER2 positivity when relapsed. Data of patients affected by HER2-positive mBC, treated with pertuzumab and/or trastuzumab-emtansine (T-DM1) in a real-world settin...
12 CitationsSource
#1Gustavo Nader MartaH-Index: 14
#2Icro Meattini (UniFI: University of Florence)H-Index: 22
Abstract null null Purpose null Post mastectomy radiation therapy (PMRT) reduces locoregional recurrence (LRR) and breast cancer mortality for selected patients. Bolus overcomes the skin-sparing effect of external-beam radiotherapy, ensuring adequate dose to superficial regions at risk of local recurrence (LR). This systematic review summarizes the current evidence regarding the impact of bolus on LR and acute toxicity in the setting of PMRT. null null null Results null 27 studies were included....
#9P. Franco (University of Eastern Piedmont)H-Index: 1
Breast conserving surgery (BCS) plus radiation therapy (RT) or mastectomy have shown comparable oncological outcomes in early-stage breast cancer and are considered standard of care treatments. Postmastectomy radiation therapy (PMRT) targeted to both the chest wall and regional lymph nodes is recommended in high-risk patients. Oncoplastic breast conserving surgery (OBCS) represents a significant recent improvement in breast surgery. Nevertheless, it represents a challenge for radiation oncologis...
1 CitationsSource
#1Pietro GentileH-Index: 36
#2Marco BerniniH-Index: 18
Last. Claudio CalabreseH-Index: 13
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1 CitationsSource