Vitali Moiseenko
University of California, San Diego
CancerInternal medicineRadiologyUrologySurgeryPathologyOncologyRadiation treatment planningProstateProstate cancerRectumToxicityNuclear medicinePlanning target volumeDose distributionNormal tissueRadiation therapyBreast cancerMedicineDosimetryComplication
295Publications
33H-index
4,528Citations
Publications 274
Newest
#1Whitney Sumner (UCSD: University of California, San Diego)H-Index: 2
#2Xenia Ray (UCSD: University of California, San Diego)H-Index: 2
Last. Ida Deichaite (UCSD: University of California, San Diego)H-Index: 8
view all 7 authors...
Purpose/Objective(s) null Optimizing the therapeutic ratio for radiation therapy (RT) in head and neck squamous cell carcinoma (HNSCC) is uniquely challenging owing to high rates of early and late toxicity involving nearby organs at risk (OAR). These toxicities have a profound impact on treatment compliance and quality of life. Emerging evidence suggests that RT dose alone cannot fully account for the variable severity of RT-related adverse events (rtAEs) observed in HNSCC patients. Next-generat...
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Purpose/Objective(s) null SRS for brain metastases is associated with a high rate (52%-64%) of cognitive deterioration. We performed a phase II clinical trial of critical white matter and hippocampal sparing brain SRS in patients with limited brain metastases, to improve cognitive preservation. We present feasibility of this approach and interim results. null null null Materials/Methods null Adult patients with limited volume ( null 6 months, pathologic confirmation of malignancy. Prior WBRT was...
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#6J. Yu (UCSD: University of California, San Diego)
#7A.S. Qian (UCSD: University of California, San Diego)
PURPOSE/OBJECTIVE(S) Impairment in fine motor skills (FMS), including motor speed and coordination, can occur after brain radiotherapy. FMS are essential for activities of daily living including writing, typing, and eating. Using a normal tissue complication probability (NTCP) framework, we sought to determine dosimetric predictors of FMS decline in a prospective cohort of brain tumor patients treated with RT. MATERIALS/METHODS On a prospective clinical trial, 52 primary brain tumor patients rec...
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#1Michael Connor (UCSD: University of California, San Diego)H-Index: 9
#2M. Cornell (UCSD: University of California, San Diego)H-Index: 5
Last. Parag Sanghvi (UCSD: University of California, San Diego)H-Index: 12
view all 5 authors...
PURPOSE/OBJECTIVE(S) Xerostomia and its effects are significant challenges for patients receiving radiation therapy (RT) for head and neck cancers (HNC). Submandibular gland (SMG) transfer has demonstrated promise in reduction of subjective and objective xerostomia. However, SMG transfer investigations have largely employed conventional RT or adjuvant RT, with little evaluation in patients treated with definitive modern RT. Furthermore, there has been no assessment of whether anatomic changes du...
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Purpose/Objective(s) null Attention and processing speed, an important neurocognitive function, is subserved in the brain by critical white matter (WM): the corpus callosum (CC) and intra-hemispheric white matter tracts (IHWM). We sought to characterize the dose-response relationship of these structures with decline in attention/processing speed at 6 months post-RT in patients with primary brain tumors, with particular attention to low doses. null null null Materials/Methods null On a prospectiv...
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#1C. Bojechko (UCSD: University of California, San Diego)H-Index: 21
#2T.J. Nelson (UCSD: University of California, San Diego)H-Index: 3
Last. Vitali Moiseenko (UCSD: University of California, San Diego)H-Index: 33
view all 4 authors...
PURPOSE For pelvic and abdominal treatments, excess dose to the bowel can result in acute toxicities. Current estimates of bowel toxicity are based on pre-treatment dose-volume histogram data. However, the actual dose the bowel receives depends on interfraction variations, such as patient anatomy changes. We propose a method to model bowel toxicities, incorporating in vivo patient information using transit electronic portal imaging device (EPID) images. METHODS AND MATERIALS For 63 patients trea...
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#1Grace S. Ahn (UCSD: University of California, San Diego)H-Index: 2
#2Andrew Bruggeman (UCSD: University of California, San Diego)H-Index: 6
Last. Ajay Sandhu (UCSD: University of California, San Diego)H-Index: 17
view all 8 authors...
BACKGROUND Radiation therapy plays an important role for symptom palliation for intrathoracic malignancies ineligible for curative-intent therapy. Limited data exists regarding the role of stereotactic body radiation therapy (SBRT) versus conformal radiation in intrathoracic tumors for palliation. We report the efficacy of hypofractionated RT (or palliative SBRT) in the symptom management and durable control of lung and non-lung intrathoracic tumors. METHODS We performed a retrospective review o...
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#1Xenia Ray (UCSD: University of California, San Diego)H-Index: 2
#2Whitney Sumner (UCSD: University of California, San Diego)H-Index: 2
Last. Vitali Moiseenko (UCSD: University of California, San Diego)H-Index: 33
view all 6 authors...
PURPOSE The purpose of this study was to evaluate if HPV status serves as an independent predictor of early and late dysphagia outcomes when considered alongside standard patient characteristics and dose metrics for head and neck cancer patients treated with radiotherapy. METHODS AND MATERIALS The age, sex, smoking history, cancer type (oropharyngeal vs non-oropharyngeal), HPV status, and early and late dysphagia outcomes were obtained for 99 retrospective head and neck cancer patients treated a...
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#1Xenia RayH-Index: 2
#2Whitney SumnerH-Index: 2
Last. Vitali MoiseenkoH-Index: 33
view all 6 authors...
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#1Katarína Furmanová (Masaryk University)H-Index: 7
#2Ludvig Paul Muren (Aarhus University Hospital)H-Index: 32
Last. Renata Georgia Raidou (TU Wien: Vienna University of Technology)H-Index: 6
view all 7 authors...
Abstract Radiotherapy (RT) requires meticulous planning prior to treatment, where the RT plan is optimized with organ delineations on a pre-treatment Computed Tomography (CT) scan of the patient. The conventionally fractionated treatment usually lasts several weeks. Random changes (e.g., rectal and bladder filling in prostate cancer patients) and systematic changes (e.g., weight loss) occur while the patient is being treated. Therefore, the delivered dose distribution may deviate from the planne...
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