Lorenzo Livi
University of Florence
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyRandomized controlled trialMedical physicsMetastatic breast cancerHead and neck cancerChemotherapyConcomitantProstate cancerRadiosurgeryPartial Breast IrradiationToxicityNuclear medicineIn patientRadiation therapyBreast cancerMedicine
541Publications
28H-index
3,852Citations
Publications 541
Newest
#1Laura PizzutiH-Index: 20
#2Maddalena BarbaH-Index: 31
Last. Clara Natoli (University of Chieti-Pescara)H-Index: 32
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In metastatic breast cancer (mBC), the change of human epidermal growth factor receptor 2 (HER2) status between primary and metastatic lesions is widely recognized, however clinical implications are unknown. Our study address the question if relevant differences exist between subjects who preserve the HER2 status and those who gain the HER2 positivity when relapsed. Data of patients affected by HER2-positive mBC, treated with pertuzumab and/or trastuzumab-emtansine (T-DM1) in a real-world settin...
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#1Pierluigi BonomoH-Index: 20
#2Isacco DesideriH-Index: 17
Last. Lorenzo LiviH-Index: 28
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#1Beatrice DettiH-Index: 20
#2Silvia ScocciantiH-Index: 19
Last. Lorenzo LiviH-Index: 28
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BACKGROUND High-grade gliomas are among the most aggressive central nervous system primary tumors, with a high risk of recurrence and a poor prognosis. Re-operation, re-irradiation, chemotherapy are options in this setting. No-best therapy has been established. Bevacizumab was approved on the basis of two Phase 2 trials that evaluated its efficacy in patients with recurrent glioblastoma. MATERIALS AND METHODS We have retrospectively review data of patients with high-grade glioma treated at our i...
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#1Beatrice DettiH-Index: 20
#2G. StocchiH-Index: 2
Last. Lorenzo LiviH-Index: 28
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BACKGROUND Patients who received a kidney transplant (KT) are described in literature as a group with a higher incidence of malignant neoplasms compared to the general population. Cancer development after KT has become a major issue, as a remarkable percentage of patients are diagnosed with cancer. Treatment of prostate cancer (PCa) in renal transplant recipients (RTRs) is a challenging issue that has been discussed by many authors over the years, but evidence is sparse and often includes confli...
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#1Silvia ScocciantiH-Index: 19
#2Emanuela OlmettoH-Index: 9
Last. Lorenzo LiviH-Index: 28
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BACKGROUND To define efficacy and toxicity of Immunotherapy (IT) with stereotactic radiotherapy (SRT) including radiosurgery (RS) or hypofractionated SRT (HFSRT) for brain metastases (BM) from Non-Small Cell Lung Cancer (NSCLC) in a multicentric retrospective study from AIRO (Italian Association of Radiotherapy and Clinical Oncology). METHODS NSCLC patients with BM receiving SRT+IT and treated in 19 Italian centers were analysed and compared with a control group of patients treated with exclusiv...
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Breast conserving surgery (BCS) plus radiation therapy (RT) or mastectomy have shown comparable oncological outcomes in early-stage breast cancer and are considered standard of care treatments. Postmastectomy radiation therapy (PMRT) targeted to both the chest wall and regional lymph nodes is recommended in high-risk patients. Oncoplastic breast conserving surgery (OBCS) represents a significant recent improvement in breast surgery. Nevertheless, it represents a challenge for radiation oncologis...
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#1Rossella Rubino (UniFI: University of Florence)
#2Andrea Marini (UniFI: University of Florence)
Last. Alessandro Peri (UniFI: University of Florence)H-Index: 35
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Purpose Immune checkpoint inhibitors have opened a new scenario in the treatment of cancer. These agents can elicit adverse events, which may affect different systems and organs, including the endocrine system. The aims of this study were to evaluate the impact of the anti-PD-1 molecules nivolumab and pembrolizumab on endocrine toxicity and on patient outcome. Methods A retrospective and multicentre study was designed, which involved a total of 251 patients affected by different tumors (mostly n...
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#1Isacco Desideri (UniFI: University of Florence)H-Index: 17
#2Carlotta Becherini (UniFI: University of Florence)H-Index: 9
Last. Pierluigi Bonomo (UniFI: University of Florence)H-Index: 20
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Locally advanced Head and neck squamous cell carcinoma (SCCHN) represents a common oncologic pathology in older adults (OA). While radiotherapy represents a cornerstone in this context, it is unclear what is the optimal radiation regimen for SCCHN in the palliative setting, especially for OA. This article addresses issues related to palliative radiotherapy (PRT) in this setting with a focus on treatment modalities and toxicity. We also explore the use of quality of life and geriatric assessment ...
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#1Beatrice DettiH-Index: 20
#2Angela Sardaro (University of Bari)H-Index: 8
Last. Lorenzo LiviH-Index: 28
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Abstract Penile metastasization is an uncommon condition, mostly derived from primitive advanced abdominal cancers, with disabling symptoms. Palliative treatment, in reason of poor prognosis patients, is frequently surgical with destructive management. We report two cases of penile metastasis, from primitive prostatic adenocarcinoma and primitive urothelial carcinoma, effectively managed with radiation treatment at our institution. A three-dimensional conformal radiation therapy with 42 Gy to th...
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#2Giulia MarvasoH-Index: 14
Last. Piet OstH-Index: 41
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Abstract Background and purpose Between 30% and 47% of patients treated with definitive radiotherapy (RT) for prostate cancer are at risk of intraprostatic recurrence during follow-up. Re-irradiation with stereotactic body RT (SBRT) is emerging as a feasible and safe therapeutic option. However, no consensus or guidelines exist on this topic. The purpose of this ESTRO ACROP project is to investigate expert opinion on salvage SBRT for intraprostatic relapse after RT. Materials and Methods A 40-it...
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