Daniel E. Gustavson
University of California, Berkeley
Developmental psychologyNeuropsychologyAssociation (psychology)PsychologyHeritabilityTwin studyCognitionCognitive psychologyWorking memoryExecutive functionsDiseaseMiddle ageImpulsivityCognitive declineCognitive impairmentAudiologyAnxietyClinical psychologyMedicineBiomarker (medicine)
63Publications
16H-index
863Citations
Publications 52
Newest
#1Mark Sanderson-Cimino (UCSD: University of California, San Diego)H-Index: 6
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 18 authors...
Objective: Abnormal white matter (AWM) on magnetic resonance imaging is associated with cognitive performance in older adults. We explored cognitive associations with AWM during late-midlife. Method: Participants were community-dwelling men (n = 242; M = 61.90 years; range = 56-66). Linear-mixed effects regression models examined associations of total, periventricular, and deep AWM with cognitive performance, controlling for multiple comparisons. Models considering specific cognitive domains con...
Source
#1Riki E Slayday (SDSU: San Diego State University)
#2Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
Last. Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
view all 14 authors...
OBJECTIVE Heavy alcohol consumption is associated with poorer cognitive function in older adults. Although understudied in middle-aged adults, the relationship between alcohol and cognition may also be influenced by genetics such as the apolipoprotein (ApoE) e4 allele, a risk factor for Alzheimer's disease. We examined the relationship between alcohol consumption, ApoE genotype, and cognition in middle-aged adults and hypothesized that light and/or moderate drinkers (≤2 drinks per day) would sho...
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#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
Last. William S. KremenH-Index: 70
view all 13 authors...
Objective: To test the hypothesis that individual differences in episodic memory and verbal fluency in cognitively normal middle-aged adults will predict progression to amnestic MCI after 6 years. Method: The cohort analyzed here included 842 male twins who were cognitively normal at baseline (M=56 years), completed measures of episodic memory and verbal fluency at baseline and again 6 years later (M=62 years). Results: Poor episodic memory predicted progression to both amnestic MCI (OR=4.42, 95...
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#1Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
#2Sean N. Hatton (UCSD: University of California, San Diego)H-Index: 22
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 20 authors...
Posttraumatic stress disorder (PTSD) is known to persist, eliciting early medical co-morbidity, and accelerated aging. Although PTSD diagnosis has been found to be associated with smaller volume in multiple brain regions, posttraumatic stress (PTS) symptoms and their associations with brain morphometry are rarely assessed over long periods of time. We predicted that persistent PTS symptoms across ~24 years would be inversely associated with hippocampal, amygdala, anterior cingulate volumes, and ...
6 CitationsSource
#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2Naomi P. Friedman (CU: University of Colorado Boulder)H-Index: 28
Last. Sandra Sanchez-Roige (UCSD: University of California, San Diego)H-Index: 22
view all 6 authors...
Factor analyses suggest that impulsivity traits that capture tendencies to act prematurely or take risks tap partially distinct constructs. We applied genomic structure equation modeling to evaluat...
1 CitationsSource
#1Daniel E. Gustavson (UCLA: University of California, Los Angeles)H-Index: 16
#2Carol E. Franz (UCLA: University of California, Los Angeles)H-Index: 48
Last. William S. Kremen (UCLA: University of California, Los Angeles)H-Index: 70
view all 5 authors...
BACKGROUND: Internalizing and externalizing psychopathology factors explain much of the covariance among psychiatric conditions, especially at the level of genetic risk. However, few studies have examined internalizing and externalizing factors in middle-aged samples, especially their ability to predict later symptoms across midlife. The goals of the current study were (i) to quantify the genetic and environmental influences on internalizing and externalizing psychopathology in individuals in th...
1 CitationsSource
#1S Stevens (UCSD: University of California, San Diego)H-Index: 1
#2Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
Last. Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
view all 9 authors...
Trauma-exposed adults with high levels of posttraumatic stress symptoms (PTSS) report poorer health-related quality of life (HRQOL), but less is known about the persistence of this relationship over time. Participants from the Vietnam Era Twin Study of Aging reported on PTSS, health, and sociodemographic characteristics at average age 38; 775 participants reported having been exposed to trauma. Later, at average ages 56 and 62, mental and physical HRQOL were assessed with the Short-Form 36. Prem...
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#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2John H. Lurquin (CU: University of Colorado Boulder)H-Index: 5
Last. Akira Miyake (CU: University of Colorado Boulder)H-Index: 72
view all 7 authors...
This exploratory latent-variable study sought to identify common sources of variance between two multi-faceted important sets of constructs: executive functions (EFs) and negative thoughts/affect. One-hundred ninety-two college students completed nine tasks representing three types of EFs (inhibition, updating, and shifting) and a set of questionnaires assessing four facets of negative thought/affect (anxiety symptoms, depression symptoms, worry, and rumination). Results indicated that, although...
6 CitationsSource
#1Hong Xian (SLU: Saint Louis University)H-Index: 59
#2Brian B. Boutwell (University of Mississippi)H-Index: 24
Last. Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
view all 16 authors...
Objectives: First, we test for differences in various cognitive abilities across trajectories of body mass index (BMI) over the later life course. Second, we examine whether genetic risk factors fo...
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#1Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
view all 8 authors...
Abstract Background Stage 1 of the NIA-AA’s proposed Alzheimer’s disease (AD) continuum is defined as β-amyloid (Aβ) positive but cognitively normal. Identifying at-risk individuals before Aβ reaches pathological levels could have great benefits for early intervention. Although Aβ levels become abnormal long before severe cognitive impairments appear, increasing evidence suggests subtle cognitive changes may begin early, potentially before Aβ surpasses the threshold for abnormality. We examined ...
5 CitationsSource