Prasit Pavasant
Chulalongkorn University
Internal medicineDownregulation and upregulationEndocrinologyMolecular biologyAlkaline phosphataseNotch signaling pathwayChemistryMaterials scienceMesenchymal stem cellIn vitroImmunologyBiocompatibilityOsteoblastStem cellPeriodontal fiberChemical engineeringCancer researchSignal transductionBiologyCell biology
Publications 207
Periodontal disease is the most common oral disease in dogs. Platelet-rich fibrin (PRF) is widely utilized to facilitate soft and hard tissue healing and has been proposed in periodontal healing in small animal treatment. However, the quality and amount of autologous PRF is compromised in animals with systemic diseases. The present study aimed to evaluate the efficacy of xenologous bubaline blood-derived PRF (bPRF) on periodontal tissue healing in canine periodontal defects. Split-mouth design w...
#1Suryo Kuncorojakti (Chula: Chulalongkorn University)H-Index: 1
#2Watchareewan Rodprasert (Chula: Chulalongkorn University)H-Index: 1
Last. Chenphop Sawangmake (Chula: Chulalongkorn University)H-Index: 6
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As of 2000, the success of pancreatic islet transplantation using the Edmonton protocol to treat type I diabetes mellitus still faced some obstacles. These include the limited number of cadaveric pancreas donors and the long-term use of immunosuppressants. Mesenchymal stem cells (MSCs) have been considered to be a potential candidate as an alternative source of islet-like cell generation. Our previous reports have successfully illustrated the establishment of induction protocols for differentiat...
#1Daneeya Chaikiawkeaw (Chula: Chulalongkorn University)H-Index: 2
#2Narach Khorattanakulchai (Chula: Chulalongkorn University)H-Index: 3
Last. Prasit Pavasant (Chula: Chulalongkorn University)H-Index: 35
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Background null Recently we have generated recombinant human osteopontin (rhOPN) using a plant platform (Nicotiana benthamiana) and demonstrated, when coated on culture plates, its osteogenic induction capacity of human periodontal ligament (PDL) cells. The aim of this study is to elucidate the molecular mechanism underlying the rhOPN-induced osteogenic differentiation of human PDL cells METHODS: Full length rhOPN (FL-OPN) and three constructs of OPN containing integrin binding domain (N142), ca...
#1Peungchaleoy Thammanichanon (PSU: Prince of Songkla University)
#2Aunwaya Kaewpitak (PSU: Prince of Songkla University)
Last. Chidchanok Leethanakul (PSU: Prince of Songkla University)H-Index: 8
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OBJECTIVE The aim of this study was to quantify the temporal changes in inflammation and TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced orthodontic pain. DESIGN Orthodontic force was applied to both maxillary first molars in 8-week-old Wistar rats for 12 h, 24 h, 3 d or 7 d. The rat grimace scale (RGS) score and duration of face grooming were used to measure orthodontic pain. Western blotting was performed to assess TRPA1, TRPV1 and CGRP expression in trigeminal...
1 CitationsSource
#1Sonthaya ChaiarwutH-Index: 2
#2Jitti NiyompanichH-Index: 3
Last. Pitt SupapholH-Index: 79
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Hydroxyapatite (HAp) has recently attracted increased interest as a promising material with a wide variety of biomedical applications in orthopedics and dentistry. Meanwhile, bone tissue engineering has not been widely adopted in clinical practice because of the prevalence of postoperative infections. Therefore, enhancing the potential of HAp with antimicrobial agents would be an optional way of preventing bacteria persistence in chronic or long-term infections. Xanthone substance obtained as a ...
3 CitationsSource
#1Wanuttha Boonyayothin (Chula: Chulalongkorn University)H-Index: 2
#2Sirorut Sinnung (Chula: Chulalongkorn University)
Last. Waranyoo Phoolcharoen (Chula: Chulalongkorn University)H-Index: 14
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Denosumab, an anti-receptor activator of nuclear factor-kappa B ligand antibody (Anti-RANKL) is a fully human monoclonal antibody (mAb) available for the treatment of osteoporosis. In the present study, an anti-RANKL mAb was transiently expressed using the geminiviral expression system in Nicotiana benthamiana, and the functional activity of the plant-produced mAb was determined. The highest expression level of the plant-produced mAb was found at 8 days post infiltration and it was estimated to ...
1 CitationsSource
#2Sirirat NantavisaiH-Index: 3
Last. Chenphop SawangmakeH-Index: 6
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1 CitationsSource
#1Poranee Banyatworakul (Chula: Chulalongkorn University)
#2Thanaphum Osathanon (Chula: Chulalongkorn University)H-Index: 18
Last. Nopadon Pirarat (Chula: Chulalongkorn University)H-Index: 17
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Platelet-rich fibrin (PRF) promotes wound healing by providing the release of growth factors. Here, the influence of Thai and Murrah bubaline blood derived PRF on canine periodontal ligament cells (cPDLs) was investigated. PRF was prepared from Thai and Murrah buffaloes with single centrifugation. Results demonstrated that Thai bubaline blood derived PRF exhibited fiber-mesh like morphology and contained more platelet entrapment than Murrah bubaline blood derived PRF. Both bubaline PRFs were abl...
2 CitationsSource
#1Jitti Niyompanich (Chula: Chulalongkorn University)H-Index: 3
#2Piyachat Chuysinuan (Chulabhorn Research Institute)H-Index: 11
Last. Pitt Supaphol (Chula: Chulalongkorn University)H-Index: 79
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Poly(e-caprolactone) (PCL) scaffolds with interconnecting pore were fabricated by solvent casting and particulate leaching. Surface modification of a PCL scaffold to improve hydrophilicity was performed via layer-by-layer (LbL) deposition of poly(diallyldimethylammonium chloride) (PDADMAC) and poly(sodium 4-styrenesulfonate) (PSS) and evaluated using aniline blue staining and X-ray photoelectron spectroscopy (XPS). Aniline blue staining was performed to determine the extent of PDADMAC/PSS deposi...
#1Jeeranan Manokawinchoke (Chula: Chulalongkorn University)H-Index: 10
#2Prasit Pavasant (Chula: Chulalongkorn University)H-Index: 35
Last. Hiroshi Egusa (Tohoku University)H-Index: 27
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Abstract Objective Mechanical stimulation regulates many cell responses. The present study describes the effects of different in vitro mechanical stimulation approaches on stem cell behavior. Design The narrative review approach was performed. The articles published in English language that addressed the effects of mechanical force on stem cells were searched on Pubmed and Scopus database. The effects of extrinsic mechanical force on stem cell response was reviewed and discussed. Results Cells s...