Robin Prestwich
Leeds Teaching Hospitals NHS Trust
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyStage (cooking)Positron emission tomographyHead and neck cancerChemotherapyHead and neck squamous-cell carcinomaCarcinomaChemoradiotherapyOropharyngeal CarcinomaNuclear medicineHead and neckRadiation therapyMedicineOncolytic virusBiologyImmune system
Publications 136
#1M. Nix (Leeds Teaching Hospitals NHS Trust)H-Index: 2
#2Robin Prestwich (Leeds Teaching Hospitals NHS Trust)H-Index: 28
Last. Richard Speight (Leeds Teaching Hospitals NHS Trust)H-Index: 10
view all 3 authors...
Head and neck MR-CT deformable image registration (DIR) for radiotherapy planning is hindered by the lack of both ground-truth and per-patient accuracy assessment methods. This study assesses novel post-registration reference-free error assessment algorithms, based on local rigid re-registration of native and pseudomodality images.Head and neck MR obtained in and out of the treatment position underwent DIR to planning CT. Block-wise mutual information (b-MI) and pseudomodality mutual information...
11 CitationsSource
#1Andrew Scarsbrook (University of Leeds)H-Index: 29
#1Andrew Scarsbrook (University of Leeds)H-Index: 8
Last. Ganesh RadhakrishnaH-Index: 11
view all 8 authors...
To assess the feasibility and potential impact on target delineation of respiratory-gated (4D) contrast-enhanced 18Fluorine fluorodeoxyglucose (FDG) positron emission tomography - computed tomography (PET-CT), in the treatment planning position, for a prospective cohort of patients with lower third oesophageal cancer. Fifteen patients were recruited into the study. Imaging included 4D PET-CT, 3D PET-CT, endoscopic ultrasound and planning 4D CT. Target volume delineation was performed on 4D CT, 4...
5 CitationsSource
#1D. Bird (St James's University Hospital)H-Index: 4
#2Chirag Patel (St James's University Hospital)H-Index: 13
Last. Robin Prestwich (St James's University Hospital)H-Index: 28
view all 7 authors...
Abstract Background and purpose Involved site radiotherapy clinical target volume (CTV) for lymphoma requires an expansion to account for the absence of radiotherapy treatment-position pre-chemotherapy imaging, which is not widely implemented. This prospective imaging study aims to quantify CTV expansion required for neck radiotherapy. Materials and methods 10 patients from a prospective single centre imaging study underwent a pre-chemotherapy FDG-PET-CT in both the diagnostic and radiotherapy t...
6 CitationsSource
#1Finbar SlevinH-Index: 2
#2Ekin ErmişH-Index: 6
Last. Robin PrestwichH-Index: 28
view all 6 authors...
Introduction: The accuracy of response assessment positron emission tomography (PET)-computed tomography (CT) following radiotherapy with or without chemotherapy for laryngeal/hypopharyngeal squamous cell carcinoma is uncertain. Methods: In all, 35 patients with laryngeal or hypopharyngeal squamous cell carcinoma who were treated between 2009 and 2014 with (chemo)radiotherapy were identified. The accuracy of response assessment PET-CT was made by correlation with clinical follow-up and pathologi...
2 CitationsSource
#1D. BirdH-Index: 4
#2Chirag PatelH-Index: 13
Last. Robin PrestwichH-Index: 28
view all 7 authors...
#1M. NixH-Index: 2
#2Richard SpeightH-Index: 10
Last. Robin PrestwichH-Index: 28
view all 3 authors...
#2S. RamasamyH-Index: 6
Last. Robin PrestwichH-Index: 28
view all 7 authors...
#2James P MordenH-Index: 21
Last. Emma HallH-Index: 57
view all 20 authors...
1 CitationsSource
#1Robert Chuter (St James's University Hospital)H-Index: 19
#1Robert Chuter (St James's University Hospital)H-Index: 8
Last. Richard Speight (St James's University Hospital)H-Index: 10
view all 7 authors...
Abstract Background and purpose To assess the accuracy of gross tumour volume (GTV) delineation for head and neck squamous cell carcinoma (HNSCC) using a diagnostic position MRI (MRI-D) deformably registered to the planning CT (pCT), by comparison with a dedicated planning position MRI (MRI-RT). Material and methods Fourteen patients with HNSCC underwent a T1-weighted MRI-D and MRI-RT. A reference GTV was defined as that delineated on MRI-RT rigidly registered to pCT. GTVs were delineated on: MR...
17 CitationsSource