Paolo Barbini
University of Siena
StatisticsInternal medicineSurgeryPathologyArtificial intelligenceDermatologyLinear modelCardiologyEstimation theoryIntensive care unitMechanical ventilationMelanomaIntensive careFlow limitationMathematicsComputer scienceSimulationArtificial neural networkRespiratory systemControl theoryMedicineBiology
133Publications
22H-index
1,878Citations
Publications 133
Newest
#1Alessandra Cartocci (UNISI: University of Siena)H-Index: 4
#2Gabriele Cevenini (UNISI: University of Siena)H-Index: 32
Last. Paolo Barbini (UNISI: University of Siena)H-Index: 22
view all 3 authors...
Abstract Background Available national public data are often too incomplete and noisy to be used directly to interpret the evolution of epidemics over time, which is essential for making timely and appropriate decisions. The use of compartment models can be a worthwhile and attractive approach to address this problem. The present study proposes a model compartmentalized by sex and age groups that allows for more complete information on the evolution of the CoViD-19 pandemic in Italy. Material an...
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#1Edgardo D'Angelo (University of Milan)H-Index: 31
#2Matteo Pecchiari (University of Milan)H-Index: 16
Last. Paolo Barbini (UNISI: University of Siena)H-Index: 22
view all 5 authors...
We investigated the effects of heliox administration (80% Helium in O2) on tidal inspiratory flow limitation (tIFL) occurring in supine anesthetized spontaneously breathing rabbits, regarded as an animal model of obstructive apnea-hypopnea syndrome. 22 rabbits were instrumented to record oro-nasal mask flow, airway opening, tracheal and esophageal pressures and diaphragm and genioglossus electromyographic activities while breathing either room air or heliox, and, in 12 rabbits, also during the a...
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#1Lucio AndreassiH-Index: 28
#2Roberto PerottiH-Index: 11
Last. Paolo BarbiniH-Index: 22
view all 8 authors...
The invention relates to a non-dusting homogeneous pigment preparation which is notable in that it comprises at least 40% by weight of one or more effect pigments, from 0.5 to 60% by weight of an aldehyde resin and/or ketonic resin and from 0.1 to 10% by weight of a redispersant.
1 Citations
#1Gabriele Cevenini (UNISI: University of Siena)H-Index: 32
#2Simone Furini (UNISI: University of Siena)H-Index: 21
Last. Pietro Rubegni (UNISI: University of Siena)H-Index: 32
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Three scoring systems were considered and described for dermatological applications in which malignant and benign skin lesions have to be recognized: two models are derived from logistic regression and naive Bayes rule by rounding model parameters to their nearest integer values; the third approach defines the scoring system by a direct stepwise adding of the most significant binary risk factors. An application example of a direct score model was then developed to illustrate important aspects of...
1 CitationsSource
#1Carmen Domene (University of Oxford)H-Index: 31
#2Paolo Barbini (UNISI: University of Siena)H-Index: 22
Last. Simone Furini (UNISI: University of Siena)H-Index: 21
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Conduction through ion channels possesses two interesting features: (i) different ionic species are selected with high-selectivity and (ii) ions travel across the channel with rates approaching free-diffusion. Molecular dynamics simulations have the potential to reveal how these processes take place at the atomic level. However, analysis of conduction and selectivity at atomistic detail is still hampered by the short time scales accessible by computer simulations. Several algorithms have been de...
21 CitationsSource
#1Simone Furini (UNISI: University of Siena)H-Index: 21
#2Paolo Barbini (UNISI: University of Siena)H-Index: 22
Last. Carmen Domene ('KCL': King's College London)H-Index: 31
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Bacterial Na+ channels have been the subjects of numerous computational studies since the first experimental structure of a Na+ selective channel was solved in 2011. Molecular Dynamics simulations revealed the presence of 2 binding sites for Na+ ions, respectively at the intracellular and extracellular entrance of the selectivity filter, separated by low energy barriers. While there is a general agreement about these features, there are also important differences among the various computational ...
1 CitationsSource
#1Pietro RubegniH-Index: 3
#1Pietro Rubegni (UNISI: University of Siena)H-Index: 32
Last. M. FimianiH-Index: 17
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Background Published studies on emergency dermatology consultations are few because there are few dermatology emergency units in the world. No study has yet described the Italian situation. Objectives To quantify and characterize patients evaluated in our dermatology emergency unit from 2006 to 2011. Methods We studied personal details, diagnosis, annual trend of cases, emergency level and hospitalization of dermatology cases over the 6-year period. Results A total of 12 226 patients were evalua...
14 CitationsSource
#1Paolo Barbini (UNISI: University of Siena)H-Index: 22
#2E BarbiniH-Index: 7
Last. Gabriele Cevenini (UNISI: University of Siena)H-Index: 32
view all 4 authors...
Background Length-of-stay prediction for cardiac surgery patients is a key point for medical management issues, such as optimization of resources in intensive care units and operating room scheduling. Scoring systems are a very attractive family of predictive models, but their retraining and updating are generally critical. The present approach to designing a scoring system for predicting length of stay in intensive care aims to overcome these difficulties, so that a model designed in a given sc...
4 CitationsSource
#1Simone Furini (UNISI: University of Siena)H-Index: 21
#2Paolo Barbini (UNISI: University of Siena)H-Index: 22
Last. Carmen Domene ('KCL': King's College London)H-Index: 31
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A distinctive feature of prokaryotic Na+-channels is the presence of four glutamate residues in their selectivity filter. In this study, how the structure of the selectivity filter, and the free-energy profile of permeating Na+ ions are altered by the protonation state of Glu177 are analyzed. It was found that protonation of a single glutamate residue was enough to modify the conformation of the selectivity filter and its conduction properties. Molecular dynamics simulations revealed that Glu177...
21 CitationsSource
#1Paolo Barbini (UNISI: University of Siena)H-Index: 22
#2Gabriele Cevenini (UNISI: University of Siena)H-Index: 32
Last. E BarbiniH-Index: 7
view all 4 authors...
RATIONALE, AIMS AND OBJECTIVES: Scoring systems are frequently proposed in medicine to summarize a set of qualitative and quantitative items by means of a numeric score. Their design often requires modelling ability and subjective judgments. This can make it difficult to adapt a scoring system to a clinical setting different from that in which the system was developed. The objective of this study was to discuss an approach to derive scoring systems, which can be easily modified and matched to an...
7 CitationsSource