Mariano Suppa
Université libre de Bruxelles
AlgorithmCancerInternal medicineConfocalBiomedical engineeringSurgeryPathologyOncologyDermatologyLine fieldYoung adultHidradenitis suppurativaMelanomaSkin cancerActinic keratosisBasal cell carcinomaOptical coherence tomographyNevusMEDLINEEpidermisPopulationSkin AgingReticular DermisHigh definitionCutaneous melanomaSkin typePapillary dermisIncidence (epidemiology)Risk factorMedicine
79Publications
15H-index
665Citations
Publications 77
Newest
#1Elisa Cinotti (UNISI: University of Siena)H-Index: 18
#2Linda Tognetti (UNISI: University of Siena)H-Index: 11
Last. M. Fontaine (ULB: Université libre de Bruxelles)H-Index: 3
view all 0 authors...
BACKGROUND Early and accurate diagnosis of cutaneous squamous cell carcinoma (SCC) and actinic keratosis (AK) is fundamental to reduce their morbidity and to select the correct treatment. Line-field confocal optical coherence tomography (LC-OCT) is a new imaging device that can characterize healthy skin and basal cell carcinoma, but no large studies are available on keratinocyte cell tumours. OBJECTIVES To identify and describe LC-OCT criteria associated with SCC and AK and to compare LC-OCT fin...
Source
#1Mariano Suppa (ULB: Université libre de Bruxelles)H-Index: 15
#2M. Fontaine (ULB: Université libre de Bruxelles)H-Index: 3
Last. V. Del Marmol (ULB: Université libre de Bruxelles)H-Index: 21
view all 19 authors...
BACKGROUND Early diagnosis and subtype classification of basal cell carcinoma (BCC) are crucial to reduce morbidity and optimize treatment. Good accuracy in differentiating BCC from clinical imitators has been achieved with existing diagnostic strategies but lower performance in discriminating BCC subtypes. Line-field confocal optical coherence tomography (LC-OCT) is a new technology able to combine the technical advantages of reflectance confocal microscopy and OCT. OBJECTIVES To identify and d...
2 CitationsSource
#1Mathieu Daoud (ULB: Université libre de Bruxelles)H-Index: 1
#2Hassane Njimi (ULB: Université libre de Bruxelles)H-Index: 9
Last. V. Del Marmol (ULB: Université libre de Bruxelles)H-Index: 21
view all 9 authors...
Source
#1M. Daxhelet (ULB: Université libre de Bruxelles)H-Index: 3
#2Mathieu Daoud (ULB: Université libre de Bruxelles)H-Index: 1
Last. V. Del MarmolH-Index: 21
view all 9 authors...
Source
#1C. Lenoir (ULB: Université libre de Bruxelles)
#1Clément Lenoir (ULB: Université libre de Bruxelles)
Last. Mariano Suppa (ULB: Université libre de Bruxelles)H-Index: 15
view all 15 authors...
Line-field confocal optical coherence tomography (LC-OCT) is a newly developed non-invasive imaging technique that combines high penetration depth (500 µm, similar to conventional OCT) with high isotropic resolution (lateral 1.3 µm, axial 1.1 µm, similar to reflectance confocal microscopy [RCM]).1 Moreover, with its ability to produce images in both vertical and horizontal planes, it enables a tridimensional (3D) analysis of the skin, which can prove very useful for assessing physiological2 as w...
Source
#1Sara Gandini (IEO: European Institute of Oncology)H-Index: 68
#2Ines ZannaH-Index: 26
Last. Saverio CainiH-Index: 27
view all 13 authors...
Abstract We conducted a systematic review and meta-analysis of the association between somatic mutations of the TERT gene promoter and melanoma survival. Data from nineteen independent studies (>2,500 melanoma overall) were pooled using random effects meta-analysis models. TERT-mutated melanoma patients had a significantly worse overall survival (OS) (summary hazard ratio 1.43, 95% confidence intervals (CI) 1.05-1.95) compared to wild-type ones. The association became stronger when combining ris...
1 CitationsSource
#1Linda Tognetti (UNISI: University of Siena)H-Index: 11
#2Andrea Carraro (UNISI: University of Siena)H-Index: 1
Last. Pietro Rubegni (UNISI: University of Siena)H-Index: 32
view all 7 authors...
5 CitationsSource
#1C. Lenoir (ULB: Université libre de Bruxelles)
#2Javiera Pérez-Anker (University of Barcelona)H-Index: 5
Last. Mariano Suppa (ULB: Université libre de Bruxelles)H-Index: 15
view all 12 authors...
Line-field confocal optical coherence tomography (LC-OCT) is a recently developed non-invasive imaging technique able to combine the technical principles of conventional OCT (high in-tissue penetration and visualization of the vertical plane) and reflectance confocal microscopy (high resolution).1-3 Indeed, LC-OCT provides tridimensional images of the skin (vertical and horizontal planes) up to a 500-µm depth and features excellent isotropic resolution (lateral: 1.3 µm; axial: 1.1 µm).
Source
#1Linda Tognetti (UNISI: University of Siena)H-Index: 11
#2Elisa Cinotti (UNISI: University of Siena)H-Index: 18
Last. Pietro Rubegni (UNISI: University of Siena)H-Index: 32
view all 15 authors...
Autoimmune bullous diseases (AIBDs) still represent a considerable a source of morbidity and mortality: early identification of a specific AIBD is often difficult due to overlapping clinical and/or laboratory features and time-consuming invasive laboratory tests. We aimed to investigate the potential role of a new imaging technology, line-field confocal optical coherence tomography (LC-OCT), in the non-invasive diagnosis of AIBDs. LC-OCT was performed at lesional, perilesional and contralateral ...
Source
#1Davide Serrano (IEO: European Institute of Oncology)H-Index: 26
#2Chiara Pozzi (IEO: European Institute of Oncology)H-Index: 10
Last. Sara Gandini (IEO: European Institute of Oncology)H-Index: 68
view all 18 authors...
Obesity and diet are associated with colorectal cancer (CRC) risk, and microbiome could mediate this risk factor. To investigate this interaction, we performed a case-control study (34 CRC cases and 32 controls) and analyzed fecal microbiota composition using 16S rRNA metabarcoding and sub-sequential shotgun analyses of genomic bacterial DNA to evaluate the role of microbiome and diet in CRC etiology, taking into account vitamin D and other risk biomarkers. Dietary habits were evaluated using a ...
Source