Morikazu Onji
Ehime University
Internal medicineRadiologyEndocrinologySurgeryPathologyAntigenVirologyAntibodyImmunologyVirusHepatitisHepatitis C virusCirrhosisHepatocellular carcinomaPrimary biliary cirrhosisHepatitis B virusHepatologyMedicineBiologyImmune systemGastroenterology
508Publications
62H-index
9,903Citations
Publications 507
Newest
#1Rosanna Asselta (Humanitas University)H-Index: 39
#2Elvezia Maria Paraboschi (Humanitas University)H-Index: 16
Last. Pietro Invernizzi (University of Milano-Bicocca)H-Index: 80
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ABSTRACT Background & aims Genome-wide association studies (GWAS) in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually-dimorphic complex autoimmune disease. Methods We performed a chrX-wide association study (XWAS), including genotype data from five GWAS (from Italy, UK, Canada, China, Japan; 5,244 cases, 11,875 controls). Results Single-marker association analyses...
1 CitationsSource
#1Morikazu Onji (Ehime University)H-Index: 62
Last. Teruki Miyake (Ehime University)H-Index: 19
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Objective: To determine whether severe kyphosis is one of the risk factors of umbilical trichophytosis in elderly people. Patients and Methods: Four cases with umbilical trichophytosis in the last 3 years and all 143 patients who visited to our clinic during from April 2018 to March 2019 were included in this study. The relationship between the condition of umbilical region and kyphosis was investigated. As regards the levels of senile kyphosis, simple visual classification of the kyphosis metho...
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#1Tomohiro AkaoH-Index: 1
#2Morikazu Onji (Ehime University)H-Index: 62
Last. Teruki Miyake (Ehime University)H-Index: 19
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Aim: In 1990, an epidemiological survey by ship in some Japanese islands revealed high prevalence of hepatitis viruses and human T cell leukemia virus (HTLV). A second prevalence study of these viruses were accomplished in 2018, 28 years after initial survey. Analysis of these studies provide insights about strategies of elimination of hepatitis viruses at remote areas. Materials and methods: In 2018, prevalence of hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), and HT...
1 CitationsSource
#1Yohei Kashimoto (Ehime University)
#2Morikazu Onji (Ehime University)H-Index: 62
Last. Teru KumagiH-Index: 30
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: Two female siblings aged 87 and 90 years were clinically diagnosed as pancreatic cancer by abdominal ultrasonography and abdominal contrast-enhanced CT. Pancreatic cancer of these patients was confirmed during the autopsy. Both patients shared risk factors of pancreatic cancer; old age, diabetes, and passive smoking. Strong family history of pancreatic cancer was found in these two patients as their father and younger brother were also suffering from this cancer. The present study seems to rep...
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#1Mamun Al Mahtab (Bangabandhu Sheikh Mujib Medical University)H-Index: 11
#2Sheikh Mohammad Fazle Akbar (Toshiba)H-Index: 15
Last. Morikazu OnjiH-Index: 62
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Context Current drugs for chronic hepatitis B therapy have a poor efficacy in terms of post-treatment sustained viral suppression and generate important side effects during and after therapy. Therapeutic vaccination with HBV antigens is an attractive alternative to test. Objective Evaluating the efficacy of a therapeutic vaccine candidate (designated NASVAC) containing both hepatitis B surface antigen (HBsAg) and core antigen (HBcAg) versus pegylated interferon (Peg-IFN) in naive chronic hepatit...
24 CitationsSource
Aim: The aim of the study was to assess the implication of Zonulin, a mediator protein synthesized by intestine and the liver,in patients with chronic liver diseases. Materials and methods: Twenty-six patients with chronic liver diseases due to hepatitis C virus (HCV) and hepatitis B virus (HBV) were enrolled in this study. Out of total 26 patients, 17 were diagnosed as chronic hepatitis (CH) and 9 were patients with liver cirrhosis (LC). Twenty-four of these patients were infected with hepatiti...
1 CitationsSource
#2Morikazu Onji (Ehime University)H-Index: 62
Last. Masanori Abe (Ehime University)H-Index: 50
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: A case of severe drug-induced liver injury caused by over the counter (OTC) herb medicine, is reported here. A 40-year-old male took herb drugs "Za ga-doKowa®," "Ohta-Isan®." These two drugs contained the same two herb medicines (cinnamon, fennel). About 4 months later after taking medicine, jaundice appeared. Prothrombin time activation (PT) was 45%, aspartate transaminase (AST) was 1104 IU/l, and total bilirubin (T-bil) 14.7 mg/dL. Serum tests for hepatitis viruses (A, B, C, E) were negative...
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#1Nobuaki Azemoto (Ehime University)H-Index: 14
#2Teru Kumagi (Ehime University)H-Index: 30
Last. Yoichi Hiasa (Ehime University)H-Index: 53
view all 12 authors...
Abstract We herein report a 55-year-old woman who presented with erythema and bilateral hilar lymphadenopathy 4 months prior to the detection of pancreatic lesions on an ultrasound. A skin biopsy showed evidence of sarcoidosis. The largest lesion in the tail of the pancreas was hypoechoic on endoscopic ultrasonography (EUS). The lesion was initially iso-enhanced on contrast enhanced-EUS (CE-EUS) but subsequently became hypoenhanced. The lesion revealed heterogeneous components of both soft and h...
4 CitationsSource
#1Shinya Furukawa (Ehime University)H-Index: 26
#2Takenori SakaiH-Index: 8
Last. Yoshihiro Miyake (Ehime University)H-Index: 47
view all 18 authors...
AIMS No evidence exists regarding the association between smoking status and nocturia among patients with type 2 diabetes mellitus. We evaluated this association among Japanese patients with type 2 diabetes mellitus by post-hoc analysis. METHODS Study subjects were 817 Japanese patients with type 2 diabetes mellitus. Study subjects were considered to have nocturia if they answered “once or more” to the question: “Within one week, how many times do you typically wake up to urinate from sleeping a...
4 CitationsSource
#1Shinya Furukawa (Ehime University)H-Index: 26
#2Takenori SakaiH-Index: 8
Last. Yoshihiro Miyake (Ehime University)H-Index: 47
view all 18 authors...
: Objective Macrovascular diseases and urgency incontinence are common among Japanese patients with type 2 diabetes mellitus. However, little evidence exists regarding the association between stroke and urgency incontinence among patients with type 2 diabetes mellitus. We examined the associations between macrovascular complications and urgency incontinence among Japanese patients with type 2 diabetes mellitus. Methods The study subjects were 818 Japanese patients with type 2 diabetes mellitus. ...
3 CitationsSource