Simon Bays
Bristol Royal Infirmary
Troponin IInterquartile rangeSurgeryHemodynamicsEpinephrineAortic cross-clampHypothermiaThoraxVascular diseaseSuperior vena cava syndromeCardiac surgeryCardiopulmonary bypassMalignancyOpioidMediastinitisCatheterSuperior vena cavaTroponinAnesthesiaMedicine
Publications 3
#1Nigel HumphreysH-Index: 1
#2Simon BaysH-Index: 3
Last. Andrew R. WolfH-Index: 28
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BACKGROUND: Extreme stress and inflammatory responses to open heart surgery are associated with increased morbidity and mortality. Based on both animal and adult human data, it was hypothesized that spinal anesthesia would be more effective at attenuating these responses than conventional high dose intravenous opioid techniques in infants and young children undergoing open heart surgery. METHODS: A prospective randomized controlled clinical trial was performed in 60 children aged up to 24 months...
65 CitationsSource
#1Massimo Caputo (BRI: Bristol Royal Infirmary)H-Index: 37
#2Simon Bays (BRI: Bristol Royal Infirmary)H-Index: 3
Last. Gianni D. Angelini (BRI: Bristol Royal Infirmary)H-Index: 72
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Background The purpose of this study is to investigate the effect of cardiopulmonary bypass (CPB) temperature on myocardial reperfusion injury, oxidative stress, and inflammatory response in pediatric open heart surgery. Methods Fifty-nine children (median age 78 months; interquartile range, 39–130) undergoing correction of simple congenital heart defects were randomized to receive either hypothermic (28°C) or normothermic (35–37°C) CPB. Troponin I and 8-isoprostane, complement activation C3a, i...
73 CitationsSource
#1Simon Bays (BRI: Bristol Royal Infirmary)H-Index: 3
#2Chanaka Rajakaruna (BRI: Bristol Royal Infirmary)H-Index: 5
Last. Anthony Morgan (BRI: Bristol Royal Infirmary)H-Index: 5
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Fibrosing mediastinitis is a rare, chronic inflammatory process that can cause superior vena cava syndrome, and can mimic malignancy. We present two cases of this disease where surgical resection was not possible and review the treatment options. q 2004 Elsevier B.V. All rights reserved.
21 CitationsSource