Mahdi Aghili
Tehran University of Medical Sciences
CancerInternal medicineRadiologySurgeryOncologyHealth careRetrospective cohort studyStage (cooking)PlaceboChemotherapyBrachytherapyCapecitabineRectumNuclear medicineCoronavirus disease 2019 (COVID-19)In patientRadiation therapyColorectal cancerBreast cancerClinical trialMedicine
57Publications
9H-index
397Citations
Publications 49
Newest
#1Nima Mousavi Darzikolaee (Tehran University of Medical Sciences)H-Index: 1
#2Kasra Kolahdouzan (Tehran University of Medical Sciences)H-Index: 6
Last. Fatemeh Ebrahiminasab (Tehran University of Medical Sciences)
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INTRODUCTION: The COVID-19 pandemic has caused significant morbidity and mortality thus far. Considering the historical uses of high-voltage X-ray beams for unresolvable pneumonia, we aimed to assess whether low-dose whole-lung irradiation (WLI) could provide any benefits for patients with refractory COVID-19 pneumonia. METHODS: Eleven patients with refractory COVID-19 pneumonia were treated with WLI to a total dose of 1 Gy and compared to 11 patients in a matched control group from June to Nove...
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#1Marzieh Gomar (Tehran University of Medical Sciences)H-Index: 1
#2Masoumeh Najafi (IUMS: Iran University of Medical Sciences)
Last. Amin Jahanbakhshi (IUMS: Iran University of Medical Sciences)H-Index: 5
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INTRODUCTION Immunotherapy by checkpoint inhibitors, i.e., anti-programmed death-1(PD-1) or anti-programmed death-ligand 1 (PD-L1) antibodies, has gained more attention managing solid tumors. Pembrolizumab (an anti-PD-1 antibody) in metastatic colorectal cancer (CRC) was approved in 2017 by the US FDA. REASON FOR THE REPORT Pembrolizumab is not effective in microsatellite stable, mismatch-repair-proficient (MSS-pMMR) molecular phenotype, which comprises most CRC patients. In this report, we pres...
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#1Peiman Haddad (Tehran University of Medical Sciences)H-Index: 12
#2Reza Ghalehtaki (Tehran University of Medical Sciences)H-Index: 4
Last. Mahdi Aghili (Tehran University of Medical Sciences)H-Index: 9
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#6Shahrzad Mahdavi Izadi (Tehran University of Medical Sciences)H-Index: 1
Background: Cyclo-oxygenase-2 (COX-2), an enzyme induced in pathological states, mediates the production of prostaglandins. Celecoxib as a selective COX-2 inhibitor may affect the outcome of treatments in several cancer types. Objectives: We conducted a randomized controlled double-blind clinical trial to evaluate the toxicity and efficacy of celecoxib administered concurrently with chemoradiation in locally advanced head and neck carcinomas. Methods: Patients with locally advanced head and neck...
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#1Saeed Nemati (UT: University of Tehran)
#1Saeed Nemati (UT: University of Tehran)H-Index: 3
Last. Kazem Zendehdel (UT: University of Tehran)H-Index: 23
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Background: Iran is a high-risk area with a poor prognosis for esophageal cancer. We conducted the present study to evaluate the survival rate of esophageal cancer after the introduction of neo-adjuvant chemo-radiation at the Cancer Institute of Iran. Method: We performed a retrospective cohort study and abstracted the data of 421 patients who referred to the Cancer Institute of Iran between 2007 and 2011. Life table and Kaplan-Meier approaches were applied to estimate 1, 3, and 5-year survival ...
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#1Mahdi AghiliH-Index: 9
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#1Mahdi AghiliH-Index: 9
Last. Reza GhalehtakiH-Index: 4
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#1Ali Kazemian (Tehran University of Medical Sciences)H-Index: 7
#2Reza Ghalehtaki (Tehran University of Medical Sciences)H-Index: 4
Last. Ebrahim Esmati (Tehran University of Medical Sciences)H-Index: 6
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Background: Hypopharyngeal carcinoma (HPC) is a rare head and neck cancer which poses many therapeutic challenges. There is limited evidence regarding the outcomes of HPC treatment in Iran. Method: In this retrospective cohort study, we evaluated patients treated with chemoradiation or radiation alone, between 2007 and 2016 in the radiation oncology ward of a cancer institute affiliated to Tehran University of Medical Sciences. The design of the study was reviewed and approved by the local insti...
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#1Mohammad Reza Keramati (Tehran University of Medical Sciences)H-Index: 12
#2Behnam Behboudi (Tehran University of Medical Sciences)
Last. Mohammad Sadegh Fazeli (Tehran University of Medical Sciences)H-Index: 12
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Background: In a resource-demanding COVID-19 pandemic, guidelines can free up health care resources needed for providing better care to those with COVID-19 and other patients. This study was performed to design a guideline to manage patients with colorectal cancers during the COVID-19pandemic. Methods: To design this guideline, major topics and headings of colon and rectal cancers (CRC) were selected and included. Based on the extent of COVID-19 infection in the community and availability of hos...
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#1Mahdi Aghili (Tehran University of Medical Sciences)H-Index: 9
#2Fatemeh Jafari (Tehran University of Medical Sciences)H-Index: 6
Last. Mojtaba Vand Rajabpoor (Tehran University of Medical Sciences)H-Index: 1
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Abstract Purpose COVID-19 outbreak is not a short-time crisis, and discontinuing or postponing life-saving treatments is not logical. Brachytherapy is one of the important treatment modalities for some subsites of cancers. Therefore, we decided to consider some of the best feasible brachytherapy regimes during the pandemic. Methods and Materials We considered brachytherapy guidelines and landmark trials and selected the most efficacious indications of brachytherapy, considering the best regimens...
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