Weiping Jia
Shanghai Jiao Tong University
Internal medicineEndocrinologySurgerySingle-nucleotide polymorphismOdds ratioType 2 diabetesInsulin resistanceInsulinBody mass indexGlycemicMetabolic syndromePopulationType 2 Diabetes MellitusObesityGeneticsDiabetes mellitusMedicineBlood pressureBiologyGastroenterology
784Publications
79H-index
21.5kCitations
Publications 792
Newest
#1Shiqiao Peng (SJTU: Shanghai Jiao Tong University)H-Index: 2
#2Xiaoying Zhang (SJTU: Shanghai Jiao Tong University)H-Index: 11
Last. Jianping Ye (SJTU: Shanghai Jiao Tong University)H-Index: 72
view all 11 authors...
Abstract null null The transcription factor nuclear factor of kappa-light-chain-enhancer of activated B cells (NF-κB) is expressed in brown adipocytes, but its role remains largely unknown in the cells. This issue was addressed in current study by examining NF-κB in brown adipocytes in vitro and in vivo. NF-κB activity was increased by differentiation of brown adipocytes through elevation of p65 (RelA) expression. The transcriptional activity of NF-κB was induced by the cold stimulation with an ...
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#1Chun Cai (SJTU: Shanghai Jiao Tong University)H-Index: 2
#2Yuexing Liu (SJTU: Shanghai Jiao Tong University)H-Index: 2
Last. Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
view all 10 authors...
This cross-sectional study aimed to investigate the quality of care of diabetes in Shanghai, China. A total of 173 235 patients with type 2 diabetes in 2017 were included in the analysis. Profiles of risk factors and intermediate outcomes were determined. The patients had a mean age of 66.43 ± 8.12 (standard deviation (SD)) years and a mean diabetes duration of 7.95 ± 5.53 (SD) years. The percentage of patients who achieved the target level for HbA1c (< 7.0%) was 48.6%. Patients who achieved the...
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#1Shaobo Li (SJTU: Shanghai Jiao Tong University)
#2Haoyong Yu (SJTU: Shanghai Jiao Tong University)H-Index: 19
Last. Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
view all 9 authors...
OBJECTIVE null To explore the potential relevance of muscle mass as a variable contributor to BMI in limitations on BMI-based predictions of diabetes remission (DR) after Roux-en-Y gastric bypass (RYGB). null RESEARCH DESIGN AND METHODS null We evaluated the relationship between muscle mass and BMI in 501 patients with type 2 diabetes mellitus and overweight or obesity, of whom 186 patients who underwent RYGB were studied for determination of the role of baseline muscle mass and BMI in predictin...
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#1Jiemin PanH-Index: 10
Last. Weiping JiaH-Index: 79
view all 9 authors...
This study aimed to evaluate the influence of Jinlida granules on glycemic variability with or without metformin treatment in patients with newly diagnosed type 2 diabetes. This study was a 16-week, double-blinded, randomized, controlled clinical trial. The enrolled patients with newly diagnosed type 2 diabetes were randomly divided into four groups: control, Jinlida, metformin, and combination treatment groups. A retrospective continuous glucose monitoring (CGM) system was used for subcutaneous...
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#1Bo Xu (SJTU: Shanghai Jiao Tong University)H-Index: 3
#2Caizhi Liu (SJTU: Shanghai Jiao Tong University)
Last. Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
view all 10 authors...
Obesity, a major health care issue, is characterized by metabolic abnormalities in multiple tissues, including the skeletal muscle. Although dysregulation of skeletal muscle metabolism can strongly influence the homeostasis of systemic energy, the underlying mechanism remains unclear. We found promoter hypermethylation and decreased gene expression of fibroblast growth factor 6 (FGF6) in the skeletal muscle of individuals with obesity using high-throughput sequencing. Reduced binding of the cycl...
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#1Liu JunliH-Index: 3
#2Liping XieH-Index: 19
Last. Junxi LuH-Index: 4
view all 19 authors...
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#1Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
#2Puhong Zhang (The George Institute for Global Health)H-Index: 15
Last. Xian Li (The George Institute for Global Health)H-Index: 24
view all 7 authors...
Background Glycemic control remains suboptimal in developing countries due to critical system deficiencies. An innovative mobile health (mHealth)-enabled hierarchical diabetes management intervention was introduced and evaluated in China with the purpose of achieving better control of type 2 diabetes in primary care. null null Methods and findings A community-based cluster randomized controlled trial was conducted among registered patients with type 2 diabetes in primary care from June 2017 to J...
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#1Wei Jia (SJTU: Shanghai Jiao Tong University)H-Index: 83
#2Cynthia Rajani (UH: University of Hawaii)H-Index: 18
Last. Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
view all 4 authors...
Hyocholic acid species (HCA, hyodeoxycholic acid, and their glycine and taurine conjugated forms) comprise 80% of the composition of pig bile (Haslewood, 1956). An interesting fact about pigs is that they do not get diabetes even though they eat almost anything and in abundant amounts, a diabetes-promoting diet. The first use of pig bile for treatment of 'xiao-ke', a condition known today as diabetes, was recorded ∼400 years ago by the Chinese medical practitioners in the Compendium of Materia M...
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#2Hui Chen (SJTU: Shanghai Jiao Tong University)H-Index: 245
Context null In 2020, the terminology of metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace non-alcoholic fatty liver disease (NAFLD). Objectives: To investigate the prevalence and incidence of MAFLD and evaluate its impacts on incident extrahepatic diseases. null Methods null A total of 6,873 subjects, with a 4.6-year follow-up, were included into this study. Associations of MAFLD and NAFLD with diabetes, chronic kidney disease (CKD), and cardiovascular disease...
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#1Cheng Hu (SJTU: Shanghai Jiao Tong University)H-Index: 34
#2Weiping Jia (SJTU: Shanghai Jiao Tong University)H-Index: 79
Metabolic diseases including type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease (NAFLD), and metabolic syndrome (MetS) are alarming health burdens around the world, while therapies for these diseases are far from satisfying as their etiologies are not completely clear yet. T2DM, NAFLD, and MetS are all complex and multifactorial metabolic disorders based on the interactions between genetics and environment. Omics studies such as genetics, transcriptomics, epigenetics, proteomics,...
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