Thomas V. Colby
Mayo Clinic
RadiologySurgeryPathologyImmunohistochemistryBiopsyRespiratory diseaseLung cancerUsual interstitial pneumoniaInterstitial lung diseaseLungIdiopathic pulmonary fibrosisLung biopsyLymphangioleiomyomatosisFibrosisPulmonary fibrosisIdiopathic interstitial pneumoniaMedicinePulmonary function testingGastroenterologyDiffuse alveolar damage
Publications 477
#1Luca Richeldi (UCSC: Catholic University of the Sacred Heart)H-Index: 56
#2Mary Beth Scholand (UofU: University of Utah)H-Index: 21
Last. Ganesh Raghu (University of Washington Medical Center)H-Index: 78
view all 30 authors...
Rationale Usual interstitial pneumonia (UIP) is the defining morphology of idiopathic pulmonary fibrosis (IPF). Guidelines for IPF diagnosis conditionally recommend surgical lung biopsy (SLB) for histopathology diagnosis of UIP when radiology and clinical context are not definitive. A 'molecular diagnosis of UIP' in transbronchial lung biopsy (TBBx), the Envisia Genomic Classifier, accurately predicted histopathologic UIP. Objectives We evaluated the combined accuracy of the Envisia Genomic Clas...
2 CitationsSource
#1Sameer K Avasarala (VUMC: Vanderbilt University Medical Center)
#2Athol U. Wells (Imperial College London)H-Index: 89
Last. Fabien Maldonado (VUMC: Vanderbilt University Medical Center)H-Index: 29
view all 4 authors...
Interstitial lung diseases are a heterogenous group of disorders that are often difficult to diagnose precisely. Clinical, laboratory, radiographic, and histologic information may be needed to arrive at the correct diagnosis. The multidisciplinary discussion has been proven to be useful in this patient group. Transbronchial cryobiopsy has become a popular method for obtaining tissue samples. Over the course of the last decade, there has been a significant amount of research assessing the feasibi...
1 CitationsSource
#1Benjamin G. Wu (NYU: New York University)H-Index: 11
#2Bianca Kapoor (NYU: New York University)H-Index: 3
Last. Leopoldo N. Segal (NYU: New York University)H-Index: 18
view all 35 authors...
INTRODUCTION Workers' exposure to metalworking fluid (MWF) has been associated with respiratory disease. As part of a public health investigation of a manufacturing facility, we performed paired environmental and human sampling to evaluate cross-pollination of microbes between environment and host and possible effects on lung pathology present among workers. METHODS Workplace environmental microbiota was evaluated in air and MWF samples. Human microbiota was evaluated in lung tissue samples from...
2 CitationsSource
#1Jürgen HetzelH-Index: 21
#2Athol U. Wells (NIH: National Institutes of Health)H-Index: 89
Last. Maik Häntschel (University of Tübingen)H-Index: 5
view all 29 authors...
Introduction The accurate diagnosis of individual interstitial lung diseases (ILD) is often challenging, but is a critical determinant of appropriate management. If a diagnosis cannot be made after multidisciplinary team discussion (MDTD), surgical lung biopsy is the current recommended tissue sampling technique according to the most recent guidelines. Transbronchial lung cryobiopsy (TBLC) has been proposed as an alternative to surgical lung biopsy. Methods This prospective, multicentre, interna...
2 CitationsSource
#1Maxwell L. Smith (Mayo Clinic)H-Index: 15
#2Lida P. Hariri (Harvard University)H-Index: 25
Last. Mary Beth Beasley (Mount Sinai Health System)H-Index: 5
view all 19 authors...
CONTEXT.— Accurate diagnosis of idiopathic pulmonary fibrosis (IPF) requires multidisciplinary diagnosis that includes clinical, radiologic, and often pathologic assessment. In 2018, the American Thoracic Society, European Respiratory Society, Japanese Respiratory Society, and the Latin American Thoracic Society (ATS/ERS/JRS/ALAT) and the Fleischner Society each published guidelines for the diagnosis of IPF, which include criteria for 4 categories of confidence of a histologic usual interstitial...
Context.— Transbronchial cryobiopsy is an emerging procedure to obtain lung tissue for diagnosis of interstitial lung disease and has gained popularity because it is less invasive and has a lower r...
1 CitationsSource
#1Shajo Kunnath-Velayudhan (NewYork–Presbyterian Hospital)H-Index: 1
#2Brandon T. Larsen (Mayo Clinic)H-Index: 16
Last. Anjali Saqi (NewYork–Presbyterian Hospital)H-Index: 10
view all 8 authors...
#1Naoya Tanabe (UBC: University of British Columbia)H-Index: 16
#2John E. McDonough (Yale University)H-Index: 18
Last. James C. Hogg (UBC: University of British Columbia)H-Index: 91
view all 10 authors...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic disease with the histology of usual interstitial pneumonia (UIP). Although the pathologist's visual inspection is central in histologic assessments, three-dimensional microcomputed tomography (microCT) assessment may complement the pathologist's scoring. We examined associations between the histopathologic features of UIP and IPF in explanted lungs and quantitative microCT measurements, including alveolar surface density, total lung volume taken ...
#1Sara TomassettiH-Index: 26
#2Mauro PavoneH-Index: 6
Last. Venerino PolettiH-Index: 42
view all 16 authors...
#1Sara TomassettiH-Index: 26
#2Claudia RavagliaH-Index: 18
Last. Venerino Poletti (Aarhus University Hospital)H-Index: 42
view all 23 authors...
Summary Background Transbronchial lung cryobiopsy (TBLC) has been introduced recently in the diagnosis of interstitial lung diseases. We aimed to evaluate the prognostic significance of the distinction between idiopathic pulmonary fibrosis and other interstitial lung diseases with the use of TBLC data in multidisciplinary team (MDT) diagnosis. Methods In this single-centre, retrospective, investigator-initiated comparative study, we evaluated consecutive patients without a definite usual interst...
2 CitationsSource
Close Researchers