Lisa T. Eyler
University of California, San Diego
PsychiatryInternal medicineDevelopmental psychologyPsychologyHeritabilityTwin studyNeuroscienceCognitionAutismBipolar disorderDepression (differential diagnoses)Functional magnetic resonance imagingMoodWhite matterBrain mappingAudiologyNeuroimagingClinical psychologyMedicineSchizophreniaBiology
200Publications
47H-index
6,907Citations
Publications 198
Newest
#1Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 12 authors...
Author(s): Elman, JA; Panizzon, MS; Gillespie, NA; Hagler, DJ; Fennema-Notestine, C; Eyler, LT; McEvoy, LK; Neale, MC; Lyons, MJ; Franz, CE; Dale, AM; Kremen, WS | Abstract: The human hippocampus can be subdivided into subfields with unique functional properties and differential vulnerability to disease or neuropsychiatric conditions. Identifying genes that confer susceptibility to such processes is an important goal in developing treatments. Recent advances in automatic subfield segmentation fr...
8 CitationsSource
#1Awais Aftab (UCSD: University of California, San Diego)H-Index: 6
#2Colin A. Depp (UCSD: University of California, San Diego)H-Index: 59
Last. Lisa T. Eyler (UCSD: University of California, San Diego)H-Index: 47
view all 6 authors...
Introduction Mixed affective states in bipolar disorder have been associated with increased number of mood episodes, increased suicidality, higher rates of co-occurring conditions, and poorer response to treatments. In order to better understand mixed symptomatology in bipolar disorder, here we examine the prevalence and associations of subjectively reported states of simultaneously high sadness and high energy as well as objectively rated concurrently high depressive and manic symptoms. Methods...
Source
#1Ariel G. Gildengers (University of Pittsburgh)H-Index: 28
#2David G. Harper (Harvard University)H-Index: 27
Last. Martha Sajatovic (Case Western Reserve University)H-Index: 56
view all 4 authors...
Abstract Bipolar disorder (BD) is a prevalent mental disorder that causes disability throughout the life-span. Because of demographic trends, there is a growing population of individuals with older-age bipolar disorder (OABD). This symposium, presented by members of the International Society of Bipolar Disorders OABD taskforce, will highlight new data relevant to OABD and to aging with BD. The session chair, Martha Sajatovic, will first speak about the development of the Aging and Geriatric Expe...
Source
#1Ellen E. Lee (UCSD: University of California, San Diego)H-Index: 15
#1Ellen Lee (UCSD: University of California, San Diego)
Last. Dilip V. Jeste (UCSD: University of California, San Diego)H-Index: 127
view all 4 authors...
Introduction Persons with schizophrenia (SZ) have life expectancies that are 15-20 years shorter than the general population, primarily due to cardiovascular-related deaths. In addition to premature mortality, persons with SZ have high rates of disability largely due to cognitive deficits. While cardiometabolic risk as well as cognition are known to be associated with poor sleep and inflammation in the general population, this has not been systematically examined in persons with SZ, although SZ ...
Source
#1Laura K.M. HanH-Index: 13
#2Richard DingaH-Index: 11
Last. Lianne SchmaalH-Index: 34
view all 146 authors...
Background: Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in MDD patients, and whether this process is associated with clinical characteristics in a large multi-center international dataset. Methods: We performed a mega-analysis by pooling brain measures derived from T1-weighted MRI scans from 29 samples worldwide. Normative brain aging was estimated by predicting chronologi...
29 CitationsSource
#1Katherine E. Burdick (Brigham and Women's Hospital)H-Index: 59
#2Caitlin E. Millett (Brigham and Women's Hospital)H-Index: 5
Last. Allan H. Young ('KCL': King's College London)H-Index: 106
view all 28 authors...
4 CitationsSource
#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2Sean N. Hatton (UCSD: University of California, San Diego)H-Index: 22
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 14 authors...
Abstract Individual differences in white matter tract microstructure, measured with diffusion tensor imaging (DTI), demonstrate substantial heritability. However, it is unclear to what extent this heritability reflects global genetic influences or tract-specific genetic influences. The goal of the current study was to quantify the proportion of genetic and environmental variance in white matter tracts attributable to global versus tract-specific influences. We assessed fractional anisotropy (FA)...
10 CitationsSource
#1Ellen E. Lee (UCSD: University of California, San Diego)H-Index: 15
#2Sonia Ancoli-Israel (UCSD: University of California, San Diego)H-Index: 132
Last. Dilip V. Jeste (UCSD: University of California, San Diego)H-Index: 127
view all 7 authors...
Objectives Persons with schizophrenia, and women in particular, are at high risk for sleep disturbances and inflammatory activation. The sleep-inflammation link has been reported to be stronger in women within the general population. This study sought to examine the sleep-inflammation link in persons with schizophrenia and its relationship with demographic, clinical and cognitive variables. Design Cross-sectional case-control study. Participants Community-dwelling outpatients with schizophrenia ...
9 CitationsSource
#1Pauline FavreH-Index: 13
#2Melissa PaulingH-Index: 3
Last. Josselin HouenouH-Index: 30
view all 59 authors...
2 CitationsSource
#1Lisa T. Eyler (UCSD: University of California, San Diego)H-Index: 47
#2Jeremy A. Elman (UCSD: University of California, San Diego)H-Index: 15
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 16 authors...
BACKGROUND: Large-scale brain networks such as the default mode network (DMN) are often disrupted in Alzheimer's disease (AD). Numerous studies have examined DMN functional connectivity in those with mild cognitive impairment (MCI), a presumed AD precursor, to discover a biomarker of AD risk. Prior reviews were qualitative or limited in scope or approach. OBJECTIVE: We aimed to systematically and quantitatively review DMN resting state fMRI studies comparing MCI and healthy comparison (HC) group...
16 CitationsSource