Hermann Pavenstaedt
TonicityInternal medicineEndocrinologyPathologyGene expressionRenal physiologyRegulation of gene expressionApoptosisEnhancer bindingRenal allograft18f fdg petSmall animalCyclosporin aProgrammed cell deathPhysiologyBotanyMedicineBiologyCell biology
6Publications
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#1Laura K. Schenk (WWU: University of Münster)H-Index: 6
#2Markus M. RinschenH-Index: 23
Last. Bayram EdemirH-Index: 18
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Background/ Aims: Rat renal inner medullary collecting duct (IMCD) cells are physiologically exposed to a wide range of ambient tonicity. To maintain their function upon changes in osmolality, IMCD cells induce expression of osmoprotective and antiapoptotic genes, mainly mediated by the transcription factor Tonicity Enhancer Binding Protein (TonEBP). Some drugs like Cyclosporin-A (CsA) are discussed to interfere with the activity of TonEBP and thereby mediate their nephrotoxic effects. The aim o...
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#2Stefan ReuterH-Index: 1
Last. Michael SchaefersH-Index: 5
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