Veli K. Topkara
Columbia University
Internal medicineSurgeryCardiologyRetrospective cohort studyIntensive care medicineHemodynamicsCardiogenic shockExtracorporeal membrane oxygenationHeart failureVentricular assist deviceHeart transplantationPopulationTransplantationContinuous flowIn patientIncidence (epidemiology)Myocardial infarctionStrokeMedicineCohort
Publications 428
#1Kevin J. Clerkin (Columbia University)H-Index: 17
#2Jan M. Griffin (Columbia University)H-Index: 4
Last. Paolo C. Colombo (Columbia University)H-Index: 53
view all 15 authors...
Background null Conditional survival (CS) is a dynamic method of survival analysis that provides an estimate of how an individual's future survival probability changes based on time post-transplant, individual characteristics, and post-transplant events. This study sought to provide post-transplant CS probabilities for heart transplant recipients based on different prognostic variables and provide a discussion tool for the providers and the patients. null Methods null Adult heart transplant reci...
#1Claudio A. Bravo (UW: University of Washington)
#2Justin Fried (Columbia University)H-Index: 14
Last. L. Witer (Columbia University)H-Index: 2
view all 18 authors...
Abstract null null Background null Heart failure predisposes to intracardiac thrombus (ICT) formation. There is limited data on prevalence and impact of pre-existing ICT on postoperative outcomes in LVAD patients. We examined the risk for stroke and death in this patient population. null null null Methods null We retrospectively studied patients who were implanted with HeartMate (HM) II or HM3 between 2/2009 and 3/2019. Preoperative transthoracic echocardiograms, intraoperative transesophageal e...
#1Veli K. Topkara (Columbia University)H-Index: 33
#2Kevin J. Clerkin (Columbia University)H-Index: 17
Last. Nir Uriel (Columbia University)H-Index: 51
view all 15 authors...
BACKGROUND One of the goals of the revised 6-tiered US adult heart allocation policy was to improve risk stratification of patients to lower exception status utilization for transplant listing. We sought to define the characteristics and outcomes of waitlisted patients using exception status and to examine region- and center-level differences in utilization of exception status in the new heart allocation system. METHODS This retrospective cohort analysis of the United Network for Organ Sharing d...
#1Eric J. Stöhr (Cardiff Metropolitan University)H-Index: 15
#2Ruiping Ji (Columbia University)H-Index: 13
Last. Joshua Z. Willey (Columbia University)H-Index: 29
view all 17 authors...
Abstract BACKGROUND While rates of stroke have declined with the HeartMate3 (HM3) continuous flow (CF) left ventricular assist device (LVAD), the impact of non-pulsatile flow and artificial pulse physiology on cerebrovascular function is not known. We hypothesized that improved hemodynamics and artificial pulse physiology of HM3 patients would augment cerebrovascular metabolic reactivity (CVR) compared with HeartMate II (HMII) CF-LVAD and heart failure (HF) patients. METHODS Mean, peak systolic ...
#1Daniel BurkhoffH-Index: 75
#2Veli K. TopkaraH-Index: 33
Last. Nir UrielH-Index: 51
view all 4 authors...
This review provides a comprehensive overview of the past 25+ years of research into the development of left ventricular assist device (LVAD) to improve clinical outcomes in patients with severe end-stage heart failure and basic insights gained into the biology of heart failure gleaned from studies of hearts and myocardium of patients undergoing LVAD support. Clinical aspects of contemporary LVAD therapy, including evolving device technology, overall mortality, and complications, are reviewed. W...
2 CitationsSource
#1Douglas L. Jennings (LIU: Long Island University)H-Index: 13
#2Lauren K. Truby (Duke University)H-Index: 16
Last. Veli K. Topkara (NewYork–Presbyterian Hospital)H-Index: 33
view all 7 authors...
Introduction:Gastrointestinal bleeding (GIB) remains a common and vexing complication of left ventricular assist device (LVAD) support. Recent single-center analyses suggest that ACE inhibitors (AC...