Mauro Papotti
University of Turin
CancerInternal medicineRadiologyEndocrinologyPathologyOncologyReceptorImmunohistochemistryBiopsyLung cancerCarcinomaLungNeuroendocrine tumorsGhrelinProstate cancerAdenocarcinomaThyroid carcinomaCancer researchThyroidMedicineBiology
613Publications
98H-index
25.4kCitations
Publications 609
Newest
#1Luca Bertero (UNITO: University of Turin)H-Index: 14
#2Alessandro Gambella (UNITO: University of Turin)H-Index: 4
Last. Paola Cassoni (UNITO: University of Turin)H-Index: 56
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Aims null Novel prognostic markers are warranted for gastrointestinal stromal tumours. Caveolin-1 is a multifunctional protein that proved to be associated with outcome in multiple tumour types. Aim of this study was to investigate Caveolin-1 expression and prognostic efficacy in a series of gastrointestinal stromal tumours. null Methods null Caveolin-1 expression was assessed by immunohistochemistry in a retrospective series of 66 gastrointestinal stromal tumours representative of the different...
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#1Enrico Costantino Falco (UNITO: University of Turin)H-Index: 1
#2Lorenzo DanieleH-Index: 15
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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Ectopic adrenal rests are a rare condition which can be found in various sites, generally in the retroperitoneum or pelvis along the path of gonadal descent. Their real prevalence is unknown. Males are more commonly affected, at least in the pediatric age. Adrenal rests are usually clinically silent and incidentally found in surgical samples, mostly in the pediatric population, and rarely in adults. With the aim of increasing knowledge and estimating the prevalence of ectopic adrenocortical tiss...
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Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
view all 9 authors...
: Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms that include even rarer variants that may pose different diagnostic problems, especially in fine needle aspiration cytology (FNAC). We describe the diagnostic clues of the amyloid-rich variant of PanNETs in endoscopic ultrasound (EUS)-guided fine needle aspiration cytology (EUS-FNAC). Three cases of PanNETs with an amyloid-rich stromal component were retrieved and retrospectively reviewed. For every case, the pancreatic lesion was i...
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#1Francesca Napoli (UNITO: University of Turin)H-Index: 8
#2Angela ListìH-Index: 3
Last. Luisella Righi (UNITO: University of Turin)H-Index: 33
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Malignant pleural mesothelioma (MPM) is a rare and highly aggressive disease that arises from pleural mesothelial cells, characterized by a median survival of approximately 13–15 months after diagnosis. The primary cause of this disease is asbestos exposure and the main issues associated with it are late diagnosis and lack of effective therapies. Asbestos-induced cellular damage is associated with the generation of an inflammatory microenvironment that influences and supports tumor growth, possi...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Isabella Castellano (UNITO: University of Turin)H-Index: 27
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
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According to the 2019 WHO classification of breast tumors, neuroendocrine neoplasms (NENs) are classified into well-differentiated NE tumors (NET) and poorly differentiated NE carcinomas (NEC), while other breast cancers (BCs) of special and no special type with neuroendocrine (NE) features are not incorporated in this scheme anymore. We aimed to assess whether INSM1, a novel NE marker, could have a role in breast NEN subtyping. We selected 63 BCs operated from 2003 to 2018, classified as BCs wi...
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#1Monica Sorbini (UNITO: University of Turin)
#2Gabriele Togliatto (UNITO: University of Turin)H-Index: 18
Last. Silvia DeaglioH-Index: 66
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Abstract Background Donor-derived cell-free DNA (dd-cfDNA) is considered a reliable marker of organ damage with potential applications in the follow-up of transplant recipients. Methods In this work we present an assay based on the donor-recipient HLA-mismatch at the HLA-DRB1 locus to monitor rejection by quantifying the percentage of dd-cfDNA using a droplet digital PCR technique. A panel of probes targeting the HLA-DRB1 locus and covering >85% genetic variability was validated and used to asse...
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#2Paolo BironzoH-Index: 15
Last. Chiara RigantiH-Index: 53
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Background: Malignant pleural mesothelioma (MPM) is a highly aggressive cancer generally diagnosed at an advanced stage and characterized by a poor prognosis. The absence of alterations in druggable kinases, together with an immune-suppressive tumor microenvironment, limits the use of molecular targeted therapies, making the treatment of MPM particularly challenging. Here we investigated the in vitro susceptibility of MPM to lurbinectedin (PM01183), a marine-derived drug that recently received a...
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#1Marco VolanteH-Index: 71
#2Ida RapaH-Index: 22
Last. Mauro PapottiH-Index: 98
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The molecular mechanisms of adrenocortical carcinoma development are incompletely defined. De-regulation of cellular-to-extracellular matrix interactions and angiogenesis appear among mechanisms associated to the malignant phenotype. Our aim was to investigate, employing PCR-based array profiling, 157 molecules involved in cell-to-matrix interactions and angiogenesis in a frozen series of 6 benign and 6 malignant adrenocortical neoplasms, to identify novel pathogenetic markers. In 14 genes, a si...
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#1Massimo Salvi (Polytechnic University of Turin)H-Index: 7
#2Alessandro Mogetta (Polytechnic University of Turin)H-Index: 1
Last. Filippo Molinari (Polytechnic University of Turin)H-Index: 35
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Abstract In kidney transplantations, pathologists evaluate the architecture of both glomeruli, interstitium and tubules to assess the nephron status. An accurate assessment of glomerulosclerosis and tubular atrophy is crucial for determining kidney acceptance, which is currently based on the pathologists’ histological evaluations on renal biopsies in addition to clinical data. In this work, we present an automated algorithm, called RENTAG (Robust EvaluatioN of Tubular Atrophy & Glomerulosclerosi...
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#1Luca Bertero (UNITO: University of Turin)H-Index: 14
#2Fulvio Borella (UNITO: University of Turin)H-Index: 7
Last. Chiara Benedetto (UNITO: University of Turin)H-Index: 57
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Infection by SARS-CoV-2 has been shown to involve a wide range of organs and tissues, leading to a kaleidoscope of clinical conditions. Within this spectrum, an involvement of the fetal-maternal unit could be expected, but, so far, the histopathological evaluation of placentas delivered by women with SARS-CoV-2 infection did not show distinct hallmarks. A consecutive series of 11 placentas, delivered by 10 women with COVID-19 admitted to our Obstetrics and Gynecology clinic have been investigate...
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