Anna F. Dominiczak
University of Glasgow
GeneGenome-wide association studyInternal medicineEndocrinologySingle-nucleotide polymorphismCardiologyGenetic associationEndotheliumEssential hypertensionSpontaneously hypertensive ratDiseasePopulationStrokeNitric oxideGeneticsBioinformaticsCandidate geneMedicineBlood pressureLocus (genetics)Biology
Publications 681
#1Spoorthy Kulkarni (Cambridge University Hospitals NHS Foundation Trust)H-Index: 3
#2Anna F. DominiczakH-Index: 115
Last. Ian B. Wilkinson (University of Cambridge)H-Index: 29
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#1Bartlomiej M Guzik (Glas.: University of Glasgow)
#2Linsay McCallum (Glas.: University of Glasgow)H-Index: 11
Last. Sandosh Padmanabhan (Glas.: University of Glasgow)H-Index: 76
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BACKGROUND Left ventricular hypertrophy (LVH) is a well-known target organ damage. Concentric hypertrophy is the strongest predictor of increased risk of cardiovascular events, but the predictive value of individual echocardiographic parameters remains unclear.The aim of this study was to search for echocardiographic and hemodynamic variables associated with concentric and eccentric remodeling and their association with long-term cardiovascular outcomes. METHODS Patients with echocardiography pe...
#1Sandosh Padmanabhan (Glas.: University of Glasgow)H-Index: 76
#2Tran Quoc Bao Tran (Glas.: University of Glasgow)H-Index: 1
Last. Anna F. Dominiczak (Glas.: University of Glasgow)H-Index: 115
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Hypertension remains the largest modifiable cause of mortality worldwide despite the availability of effective medications and sustained research efforts over the past 100 years. Hypertension requires transformative solutions that can help reduce the global burden of the disease. Artificial intelligence and machine learning, which have made a substantial impact on our everyday lives over the last decade may be the route to this transformation. However, artificial intelligence in health care is s...
1 CitationsSource
#1Helen R. WarrenH-Index: 30
Last. Patricia B. MunroeH-Index: 91
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#1Sandosh Padmanabhan (Glas.: University of Glasgow)H-Index: 76
#2Anna F. Dominiczak (Glas.: University of Glasgow)H-Index: 115
The known genetic architecture of blood pressure now comprises >30 genes, with rare variants resulting in monogenic forms of hypertension or hypotension and >1,477 common single-nucleotide polymorphisms (SNPs) being associated with the blood pressure phenotype. Monogenic blood pressure syndromes predominantly involve the renin–angiotensin–aldosterone system and the adrenal glucocorticoid pathway, with a smaller fraction caused by neuroendocrine tumours of the sympathetic and parasympathetic nerv...
1 CitationsSource
#1Praveen Surendran (BHF: British Heart Foundation)H-Index: 28
#2Epic-Cvd (University of Texas Health Science Center at Houston)H-Index: 1
Last. Million Veteran Program (BHF: British Heart Foundation)
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#1Philipp BoderH-Index: 1
#2Sheon MaryH-Index: 6
Last. Christian DellesH-Index: 58
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#1Abhilash Koratala (UF: University of Florida)H-Index: 9
#2Gajapathiraju Chamarthi (UF: University of Florida)H-Index: 3
Last. Rajesh Mohandas (UF: University of Florida)H-Index: 11
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1 CitationsSource
#1Baryab Zahra (Glas.: University of Glasgow)
#2Helen Lyall (Glasgow Royal Infirmary)H-Index: 15
Last. Avril MasonH-Index: 11
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BACKGROUND A Turner Syndrome (TS) Transition clinic, Royal Hospital for Children Glasgow (RHCG), with paediatric and adult endocrinology/gynaecology teams was established in 1998 with an aim of improving health outcomes in TS throughout the lifespan. OBJECTIVE To evaluate the success of our TS transition service, focussing on evaluating established follow-up after transfer to adult services. METHODS Girls attending the TS Transition clinic at Royal Hospital for Children Glasgow, 1998-2017, were ...