Luca Frulloni
University of Verona
Internal medicineRadiologySurgeryPathologyRetrospective cohort studyIntensive care medicineImmunologyPancreatitisAcute pancreatitisPancreatic diseaseAutoimmune pancreatitisJaundicePancreasDiseasePancreatic ductPancreatic cancerIn patientIncidence (epidemiology)Diabetes mellitusMedicineGastroenterology
Publications 234
#1Elisabetta GoniH-Index: 7
#2Nicolò de PretisH-Index: 8
Last. Giulia Martina CavestroH-Index: 30
view all 8 authors...
#1David C. Whitcomb (University of Pittsburgh)H-Index: 90
#2Luca Frulloni (University of Verona)H-Index: 58
Last. Tooru Shimosegawa (Tohoku University)H-Index: 93
view all 7 authors...
Abstract Background A definition of chronic pancreatitis (CP) is needed for diagnosis and distinguishing CP from other disorders. Previous definitions focused on morphology. Advances in epidemiology, genetics, molecular biology, modeling and other disciplines provide new insights into pathogenesis of CP, and allow CP to be better defined. Methods Expert physician-scientists from the United States, India, Europe and Japan reviewed medical and scientific literature and clinical experiences. Compet...
192 CitationsSource
#1B. JaisH-Index: 1
#2Vinciane ReboursH-Index: 37
Last. Philippe LévyH-Index: 57
view all 88 authors...
Objectives Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality. Design Retrospective multinational study including SCN diagnosed between 1990 and 2014. Results 2622 patients were included. Seventy-four per cent were women, and median age at diagnosis was 58 years (16–99). Patients presented with non-specific abdominal pain (27%), pa...
146 CitationsSource
Solid pseudopapillary tumors (SPT) of the pancreas are rare neoplasms mainly affecting young women. Pancreatic serous cystadenomas (SCAs) and pancreatic neuroendocrine tumors (PanNETs) account for about 2% of all pancreatic neoplasms. The combination of these three lesions, to our knowledge, has never been described in literature. Here we report a case of combined SPT, SCA and PanNET affecting a 33-year-old woman.
2 CitationsSource
#1Michelle A. Anderson (UM: University of Michigan)H-Index: 55
#2Venkata S. Akshintala (University of Pittsburgh)H-Index: 15
Last. David C. Whitcomb (University of Pittsburgh)H-Index: 90
view all 23 authors...
Abstract Description Pain in patients with chronic pancreatitis (CP) remains the primary clinical complaint and source of poor quality of life. However, clear guidance on evaluation and treatment is lacking. Methods Pancreatic Pain working groups reviewed information on pain mechanisms, clinical pain assessment and pain treatment in CP. Levels of evidence were assigned using the Oxford system, and consensus was based on GRADE. A consensus meeting was held during PancreasFest 2012 with substantia...
40 CitationsSource
#1Riccardo NegrelliH-Index: 10
#2Giacomo AvesaniH-Index: 3
Last. Roberto Pozzi MucelliH-Index: 37
view all 6 authors...
#1María Sánchez Castañón (University of Verona)H-Index: 1
#2Valeria ZulianiH-Index: 9
Last. Luca FrulloniH-Index: 58
view all 9 authors...
Objectives Several serological markers have been reported in autoimmune pancreatitis (AIP) patients. However, only serum IgG4 (sIgG4) is available in clinical practice for AIP diagnosis. Antiamylase α antibodies (AMY-α Abs) have been proposed to diagnose AIP. This study evaluates the utility of AMY-α Abs and sIgG4 for AIP diagnosis. Methods Twenty-five AIP patients, 84 disease control groups (31 chronic pancreatitis, 30 acute pancreatitis, 23 pancreatic adenocarcinoma), and 59 healthy donors wer...
6 CitationsSource
#2P. CampagnolaH-Index: 6
Last. Luca Frulloni (University of Verona)H-Index: 58
view all 3 authors...
The most common etiology for AP are gallstones and alcohol abuse. Other causes include iatrogenic injury (i.e. post-ERCP), metabolic and autoimmune disorders, inherited disorders, neoplasia (even intraductal papillary mucinous neoplasiaIPMN), anatomical abnormalities, infections, ischaemia, trauma and drugs (87). Additional investigations after recovery from the acute episode are recommended in patients with an episode of AP classified as idiopathic (68).
4 CitationsSource
#1Raffaele Pezzilli (UNIBO: University of Bologna)H-Index: 56
#2Alessandro ZerbiH-Index: 57
Last. Gianpaolo Balzano (UniSR: Vita-Salute San Raffaele University)H-Index: 44
view all 20 authors...
Abstract This Position Paper contains clinically oriented guidelines by the Italian Association for the Study of the Pancreas (AISP) for the diagnosis and treatment of severe acute pancreatitis. The statements were formulated by three working groups of experts who searched and analysed the most recent literature; a consensus process was then performed using a modified Delphi procedure. The statements provide recommendations on the most appropriate definition of the complications of severe acute ...
61 CitationsSource