Rabah Iratni
United Arab Emirates University
CancerMolecular biologyChemistryApoptosisImmunologyAutophagyDiseaseArabidopsisProgrammed cell deathCancer researchNitric oxideViability assayGeneticsBiochemistryBotanyCell growthMedicineBiologyCell biologyCancer cellPharmacology
66Publications
21H-index
1,957Citations
Publications 64
Newest
Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal skin diseases, affecting up to one fifth of the population in developed countries. AD is characterized by recurrent pruritic and localized eczema with seasonal fluctuations. AD initializes the phenomenon of atopic march, during which infant AD patients are predisposed to progressive secondary allergies such as allergic rhinitis, asthma, and food allergies. The pathophysiology of AD is complex; onset of the d...
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#1Halima Alsamri (United Arab Emirates University)H-Index: 3
#2Hussain El Hasasna (United Arab Emirates University)H-Index: 4
Last. Rabah Iratni (United Arab Emirates University)H-Index: 21
view all 9 authors...
Carnosol, a natural polyphenol, abundant in edible plants such as sage, rosemary and oregano, has shown promising anticancer activity against various type of cancers. Nonetheless, very little is known about its molecular mechanism of action or about its downstream target(s). We have previously shown that carnosol inhibits cellular proliferation, migration, invasion, and metastasis as well as triggers autophagy and apoptosis in the highly invasive MDA-MB-231 breast cancer cells. Here, we report t...
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#1Zena WehbeH-Index: 4
#2Maya WehbeH-Index: 1
Last. Ali H. EidH-Index: 26
view all 7 authors...
As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID-19. Several vaccines, including mRNA, vector-based vaccines, and inactivated vaccines, have been approved for emergency use in various countries. However, the slow roll-out of vaccines and insufficient global supply remains a challenge to turn the tide of the pandemic. Moreover, vaccines are important tools for prevent...
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#1Ali Dakroub (AUB: American University of Beirut)H-Index: 2
#2Suzanne A. Nasser (Beirut Arab University)H-Index: 5
Last. Ali H. Eid (Qatar University)H-Index: 26
view all 9 authors...
Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been implicated in vascular remodeling, vascular inflammation, and atherosclerosis, all of which pose increased risks of cardiovascular events. In this context, increased levels of visfatin have been correlated with several upregulated pro-inflammatory mediators, such as IL-1, IL-1Ra, IL-6, IL-8, and TNF-α. Furthermore, visfatin i...
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#1Adel Hajj Ali (AUB: American University of Beirut)H-Index: 2
#2Nour K Younis (AUB: American University of Beirut)H-Index: 4
Last. Ali H. Eid (Qatar University)H-Index: 26
view all 12 authors...
Cardiovascular disease (CVD) remains the primary cause of global morbidity and mortality. CVD includes various life-threatening conditions such as myocardial infarction, stroke and peripheral arterial diseases. In this context, atherosclerosis continues to play the principal role in the pathogenesis of these conditions. Atherosclerosis emanates from a set of modifiable and non-modifiable risk factors that include age, male gender, family history, obesity, smoking, diabetes mellitus and hypertens...
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#1Khalid Muhammad (United Arab Emirates University)H-Index: 13
#2Mohammed Akli Ayoub (United Arab Emirates University)H-Index: 26
Last. Rabah Iratni (United Arab Emirates University)H-Index: 21
view all 3 authors...
Cardiovascular disease (CVD) is one of the leading cause of death worldwide. Chronic atherosclerosis induced vascular inflammation and perturbation of lipid metabolism is believed to be a major cause of CVD. Interplay of innate and adaptive Immune system has been interwined with various risk factors associated with the initiation and progression of atherosclerosis in CVD. A large body of evidences indicate a correlation between immunity and atherosclerosis. Retention of plasma lipoproteins in ar...
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#1Halima Alsamri (United Arab Emirates University)H-Index: 3
#2Khawlah Athamneh (United Arab Emirates University)H-Index: 6
Last. Rabah Iratni (United Arab Emirates University)H-Index: 21
view all 5 authors...
Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in traditional medicine for the management and treatment of many ailments including hemorrhoids, wound healing, diarrhea, ulcer, and eye inflammation. This plant is rich in various classes of phytochemicals including flavonoids, tannins, polyphenolic compounds, organic acids, and ...
2 CitationsSource
#1Rabah Iratni (United Arab Emirates University)H-Index: 21
#2Mohammed Akli Ayoub (United Arab Emirates University)H-Index: 26
The concept of drug repurposing and Sildenafil or blue pill are tightly linked over the years. Indeed, in addition to its initial clinical application as an anti-hypertensive drug in the pulmonary system, Sildenafil is also known for its beneficial effects in erectile dysfunction. Moreover, evidence have been accumulated to support its value in anti-cancer therapy either alone or in a combination with other clinically efficient chemotherapy drugs. In this review, we focused on the old and recent...
1 CitationsSource
#1Arshida AshrafH-Index: 2
#2Priti MudgilH-Index: 15
Last. Mohammed Akli AyoubH-Index: 26
view all 7 authors...
The molecular basis of the anti-diabetic properties of camel milk reported in many studies and the exact active agent are still elusive. Recent studies have reported effects of camel whey proteins (CWP) and their hydrolysates (CWPH) on the activities of dipeptidyl peptidase IV (DPP-IV) and the human insulin receptor (hIR). In this study, CWPH were generated, screened for DPP-IV binding in silico and inhibitory activity in vitro, and processed for peptide identification. Furthermore, pharmacologi...
1 CitationsSource
#1Tariq Zeyad (United Arab Emirates University)
Last. Rabah Iratni (United Arab Emirates University)H-Index: 21
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Abstract The recently introduced 6-dyes Yfiler® Plus multiplex kit which includes 27 Y-STR loci has been used to study 436 UAE Arab male individuals. In addition to the 17 Y-STRs traditionally used in Yfiler® multiplex kit, Yfiler® Plus has ten additional Y-STRs. It includes seven rapidly mutating Y-STRs (RM Y-STRs) namely DYS560, DYS576, DYS627, DYS518, DYS449 and DYF387S1ab, and three moderately mutating Y-STRs namely DYS481, DYS533 and DYS460. The RM Y-STRs were already proven to be powerful ...
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