Carl Heneghan
University of Oxford
Internal medicineHealth careRandomized controlled trialIntensive care medicinePhysical therapyPediatricsSystematic reviewEvidence-based medicineAdverse effectAlternative medicinePsychological interventionMEDLINEPopulationPrimary careFamily medicineClinical trialMedicineBlood pressureMeta-analysis
561Publications
73H-index
13.7kCitations
Publications 533
Newest
#1Ali Anis (John Radcliffe Hospital)
#2Carl Heneghan (University of Oxford)H-Index: 73
Last. Georgia C. Richards (University of Oxford)H-Index: 5
view all 5 authors...
BACKGROUND The global burden of cardiovascular disease (CVD) is forecast to increase, and anticoagulants will remain important medicines for its management. Coroners' Prevention of Future Death reports (PFDs) provide valuable insights that may enable safer and more effective use of these agents. AIM To identify CVD-related PFDs involving anticoagulants. DESIGN AND SETTING Retrospective observational study of coronial case reports in England and Wales between 2013 and 2019. METHOD We screened 303...
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#1Gwenllian Wynne-Jones (Keele University)H-Index: 17
#2H. Myers (Keele University)H-Index: 16
Last. Simon Wathall (Keele University)H-Index: 8
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Introduction null People presenting with shoulder pain considered to be of musculoskeletal origin is common in primary care but diagnosing the cause of the pain is contentious, leading to uncertainty in management. To inform optimal primary care for patients with shoulder pain, the study aims to (1) to investigate the short-term and long-term outcomes (overall prognosis) of shoulder pain, (2) estimate costs of care, (3) develop a prognostic model for predicting individuals’ level and risk of pai...
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#1Ranin Soliman (University of Oxford)H-Index: 2
#2Alaa Elhaddad (Cairo University)H-Index: 12
Last. Carl Heneghan (University of Oxford)H-Index: 73
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INTRODUCTION There is a lack ofevidence about resource use and costs of childhood cancer care in Egypt. Knowledge about resource use/costs can help in better resource planning to improve care and outcomes efficiently. In this study, we estimated patterns and trends of hospital resource use and costs for children with cancer (n = 8886, aged 0-18 years) treated at Children's Cancer Hospital, Egypt (CCHE), between 2013 and 2017, by ICCC-3 groups, at one and three years post-diagnosis. METHODS We es...
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#2Carl Heneghan (University of Oxford)H-Index: 73
Last. Tom Jefferson (University of Oxford)H-Index: 51
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RATIONALE FOR THE REVIEW: Air travel may be associated with viruses spread via infected passengers and potentially through in-flight transmission. Given the novelty of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, transmission associated with air travel is based on transmission dynamics of other respiratory viruses. Our objective was to provide a rapid summary and evaluation of relevant data on SARS-CoV-2 transmission aboard aircraft, report policy implications and to h...
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#1Rafael Perera (University of Oxford)H-Index: 68
#2Richard Stevens (University of Oxford)H-Index: 43
Last. FD Richard Hobbs (University of Oxford)H-Index: 57
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Background Long-term monitoring is important in chronic condition management. Despite considerable costs of monitoring, there is no or poor evidence on how, what and when to monitor. The aim of this study was to improve understanding, methods, evidence base and practice of clinical monitoring in primary care, focusing on two areas: chronic kidney disease and chronic heart failure. Objectives The research questions were as follows: does the choice of test affect better care while being affordable...
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#1Alex Hodkinson (NIHR: National Institute for Health Research)
#2Carl Heneghan (University of Oxford)H-Index: 73
Last. Maria Panagioti (NIHR: National Institute for Health Research)H-Index: 30
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BACKGROUND Schizophrenia and bipolar disorder are severe mental illnesses which are highly prevalent worldwide. Risperidone and Paliperidone are treatments for either illnesses, but their efficacy compared to other antipsychotics and growing reports of hormonal imbalances continue to raise concerns. As existing evidence on both antipsychotics are solely based on aggregate data, we aimed to assess the benefits and harms of Risperidone and Paliperidone in the treatment of patients with schizophren...
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#1Carl Heneghan (University of Oxford)H-Index: 73
#2Annette Plüddemann (University of Oxford)H-Index: 27
Last. Tom Jefferson (University of Oxford)H-Index: 51
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Abstract null Background null Vaccine uptake varies substantially, and resources to promote the uptake of vaccines differ widely by country and income level. As a result, immunization rates are often suboptimal. There is a need to understand what works, particularly in low- and middle-income countries and other settings where resources are scarce. null Methods null We plan to conduct a scoping review of interventions designed to increase vaccination uptake null We will include systematic reviews...
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#1Carl Heneghan (University of Oxford)H-Index: 73
#2Kamal R Mahtani (University of Oxford)H-Index: 28
Patients with diabetic foot ulcers are at high risk of lower leg amputations, which have a considerable impact on their quality of life. Identifying strategies to reduce this risk are a priority. Growing evidence suggests that supporting these patients through multidisciplinary teams (MDTs) may reduce the risk of amputations. A new systematic review gives insights into how these teams should be composed . The global prevalence of diabetes and its associated complications has risen substantially,...
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#1Margaret McCartney (St And: University of St Andrews)H-Index: 16
#2Frank Sullivan (St And: University of St Andrews)H-Index: 50
Last. Carl Heneghan (University of Oxford)H-Index: 73
view all 3 authors...
On 16th March 2020, the UK government published “Guidance on social distancing for everyone in the UK”,1 which asked people in particular groups to be “particularly stringent in following social distancing measures”. These groups included all people over the age of 70, and under the age of 70 with particular health conditions. People offered influenza vaccines were part of this cohort (which includes people with heart disease, chronic respiratory disease, obesity and major mental illness) as wel...
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#1Tom Jefferson (University of Oxford)H-Index: 51
#2Elizabeth A Spencer (University of Oxford)H-Index: 60
Last. Carl Heneghan (University of Oxford)H-Index: 73
view all 9 authors...
Abstract null Background null The transmission role of SARS-Cov-2 infected persons who develop symptoms post testing (pre symptomatics) or not at all throughout the course of positivity (asymptomatics) is unknown. We carried out a systematic review of available evidence to determine whether they were infectious or not and if so for how long and their probable contribution to the pandemic spread of SARS-CoV-2. null Methods null We searched LitCovid, medRxiv, Google Scholar and the WHO Covid-19 da...
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