Ariel Schlaen
Austral University
OphthalmologyInternal medicineSurgeryPathologyRandomized controlled trialPediatricsAdverse effectUveitisCorticosteroidRetinitisRetinaBevacizumabVisual acuityVogt–Koyanagi–Harada diseaseDiseaseIntermediate uveitisAdalimumabMacular edemaLesionPanuveitisVogt-Koyanagi-Harada syndromeIntravitreal bevacizumabIn patientMedicine
Publications 35
#1Eric B. Suhler (OHSU: Oregon Health & Science University)H-Index: 41
#2Glenn J. Jaffe (Duke University)H-Index: 80
Last. James T. Rosenbaum (OHSU: Oregon Health & Science University)H-Index: 88
view all 26 authors...
Purpose To evaluate long-term efficacy and safety of extended treatment with adalimumab in patients with noninfectious intermediate, posterior, or panuveitis. Design Open-label, multicenter, phase 3 extension study (VISUAL III). Participants Adults who had completed a randomized, placebo-controlled phase 3 parent trial (VISUAL I or II) without treatment failure (inactive uveitis) or who discontinued the study after meeting treatment failure criteria (active uveitis). Methods Patients received su...
#2Soledad OrmaecheaH-Index: 1
Last. Ariel SchlaenH-Index: 8
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#1Maria Soledad Ormaechea (UBA: University of Buenos Aires)H-Index: 2
#2Muhammad Hassan (Stanford University)H-Index: 15
Last. Ariel Schlaen (UBA: University of Buenos Aires)H-Index: 8
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To correlate changes in subfoveal choroidal thickness (SCT) with the degree of anterior inflammatory activity in chronic Vogt-Koyanagi-Harada (VKH) disease. Anterior segment inflammation was assess...
#1Cristhian A. Urzua (University of Chile)H-Index: 6
#2Carl P. HerbortH-Index: 46
Last. Carlos Pavesio (NIHR: National Institute for Health Research)H-Index: 33
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To describe distinctive stages of Vogt-Koyanagi-Harada (VKH) disease: initial-onset acute versus chronic recurrent disease. A comprehensive literature review regarding stages and clinical presentations of VKH disease was conducted. Despite a list of signs that has been described as characteristic features of early or late phases of VKH disease, the current classification -developed by an international committee and published in 2001- does not consider a distinction regarding the time from onset ...
3 CitationsSource
#1Rupesh Agrawal (Moorfields Eye Hospital)H-Index: 30
#2Ilaria Testi (Moorfields Eye Hospital)H-Index: 4
Last. Vishali Gupta (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 37
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An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interact...
2 CitationsSource
#1Rupesh Agrawal (TTSH: Tan Tock Seng Hospital)H-Index: 30
#2Aniruddha Agarwal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 23
Last. Vishali Gupta (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 37
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ABSTRACTPurpose: To standardize a nomenclature system for defining clinical phenotypes, and outcome measures for reporting clinical and research data in patients with ocular tuberculosis (OTB).Meth...
9 CitationsSource
#1Maria Soledad Ormaechea (Stanford University)H-Index: 2
#2Muhammad Hassan (Stanford University)H-Index: 15
Last. Quan Dong Nguyen (Stanford University)H-Index: 58
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ABSTRACTIntroduction: The treatment strategies for noninfectious uveitis (NIU) aim to achieve disease remission, prevention of recurrences, and preserving vision, while minimizing the side effects ...
1 CitationsSource
#1J. Fernando Arevalo (Stellenbosch University)H-Index: 1
#2Andres F. LasaveH-Index: 16
Last. D. Ruiz-CasasH-Index: 1
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Purpose To assess the effectiveness and safety of an intravitreal injection of 1.25 mg bevacizumab (IVB) as a preoperative adjunct to small-gauge pars plana vitrectomy (PPV) compared with PPV alone in eyes with tractional retinal detachment secondary to proliferative diabetic retinopathy. Methods This prospective, double-masked, randomized, multicenter, active-controlled clinical trial enrolled 224 eyes of 224 patients between November 2013 and July 2015. All eyes underwent a baseline examinatio...
6 CitationsSource
#1Elisabetta Miserocchi (UniSR: Vita-Salute San Raffaele University)H-Index: 24
#2Lorenzo Iuliano (UniSR: Vita-Salute San Raffaele University)H-Index: 11
Last. Francesco Bandello (UniSR: Vita-Salute San Raffaele University)H-Index: 64
view all 10 authors...
ABSTRACTPurpose: To describe clinical features and outcome in bilateral acute retinal necrosis (BARN).Methods: Observational retrospective longitudinal review of ocular findings.Results: Thirty eyes of 15 patients (age 44.1 ± 15.8). Delay of involvement between eyes was 57.2 ± 105.2 months (median 3, range 0.5–360). Herpes simplex virus (HSV)-1 was the most frequent (20 eyes, 66.6%), followed by HSV-2 (five eyes, 16.7%) and varicella zoster virus (VZV, four eyes, 13.3%). Visual acuity worsened i...
9 CitationsSource