Emanuele Bosi
Vita-Salute San Raffaele University
GeneInternal medicineEndocrinologySurgeryGenomeAntibodyAutoantibodyIsletImmunologyType 2 diabetesInsulin resistanceAutoimmune diseaseInsulinAutoimmunityType 1 diabetesGeneticsDiabetes mellitusMedicineBiologyGastroenterology
Publications 286
#1Anna Giovenzana (UniSR: Vita-Salute San Raffaele University)H-Index: 4
#2Federica Vecchio (UniSR: Vita-Salute San Raffaele University)
Last. Alessandra Petrelli (UniSR: Vita-Salute San Raffaele University)H-Index: 17
view all 13 authors...
Alterations of the exocrine pancreas have been reported in type 1 diabetes, but their contribution to the pathogenesis of the disease is poorly understood. Here, we investigated markers of exocrine pancreas dysfunction in individuals at-risk of developing type 1 diabetes. Serum P-amylase and lipase levels were assessed in samples obtained from healthy controls, patients with new onset type 1 diabetes, relatives participating to the TrialNet Pathway to Prevention who were, at blood collection, au...
Arginase 2 (ARG2) is a manganese metalloenzyme involved in several tissue specific processes, from physiology to pathophysiology. It is variably expressed in extra-hepatic tissues and is located in the mitochondria. In human pancreatic beta cells, ARG2 is downregulated in type 2 diabetes. The enzyme regulates the synthesis of polyamines, that are involved in pancreas development and regulation of beta cell function. Here, we discuss several features of ARG2 and polyamines, which can be relevant ...
#1Andrea Laurenzi (UniSR: Vita-Salute San Raffaele University)H-Index: 8
#2Amelia Caretto (UniSR: Vita-Salute San Raffaele University)H-Index: 8
Last. Lorenzo Piemonti (UniSR: Vita-Salute San Raffaele University)H-Index: 70
view all 13 authors...
Purpose null To assess whether dysglycaemia diagnosed during SARS-CoV-2 pneumonia may become a potential public health problem after resolution of the infection. In an adult cohort with suspected COVID-19 pneumonia, we integrated glucose data upon hospital admission with fasting blood glucose (FBG) in the year prior to COVID-19 and during post-discharge follow-up. null Methods null From February 25th to May 15th 2020 660 adults with suspected COVID-19 pneumonia were admitted to the San Raffaele ...
#1Andrea Vecchione (CUMC: Columbia University Medical Center)H-Index: 2
#2Tatiana JofraH-Index: 10
Last. Georgia FousteriH-Index: 16
view all 28 authors...
In the attempt to understand the origin of autoantibody (AAb) production in patients with and at-risk for T1D, multiple studies have analyzed and reported alterations in follicular helper T cells (Tfh) in presymptomatic AAb-positive subjects and patients with T1D. Yet, it is still not clear whether the regulatory counterpart of Tfh cells, represented by follicular regulatory T cells (Tfr), is similarly altered. To address this question, we performed analyses in peripheral blood, spleen and pancr...
#1Sergio Di Molfetta (University of Bari)H-Index: 5
#2Emanuele Bosi (UniSR: Vita-Salute San Raffaele University)H-Index: 63
Last. Francesco Giorgino (University of Bari)H-Index: 64
view all 10 authors...
Abstract null null Aims null To investigate the relationship between single therapeutic interventions and indicators of glycemic control in the PRISMA trial, a large study comparing the effects of intensive structured SMBG (ISM) vs. active control (AC) in non-insulin-treated T2D. null null null Methods null Information was collected at four time points, corresponding to months 3, 6, 9, and 12 and visits 2, 3, 4, and 5, respectively. Data on therapeutic interventions, HbA1c levels and the number ...
#1Mara SuleimanH-Index: 1
#2Xiaoyan YiH-Index: 2
Last. Ugo BoggiH-Index: 8
view all 16 authors...
#1Julien Da SilvaH-Index: 3
#2Emanuele Bosi (UniSR: Vita-Salute San Raffaele University)H-Index: 63
Last. Ohad CohenH-Index: 25
view all 9 authors...
AIMS The MiniMed™ 670G system has been available in Europe since October 2018. Herein, the system's real-world performance in individuals with diabetes is evaluated. MATERIALS AND METHODS Data uploaded October 2018 to July 2020 by individuals living in Europe were aggregated and retrospectively analyzed. The mean Glucose Management Indicator (GMI), percentage of time spent within (TIR), below (TBR) and above (TAR) glycemic ranges, system use and insulin consumed in users with ≥10 days of SG data...
#1Katherine EspositoH-Index: 4
#2Andrea Mario BollaH-Index: 6
Last. Emanuele BosiH-Index: 63
view all 8 authors...
#1Emanuele Bosi (UniPi: University of Pisa)H-Index: 63
#2Lorella Marselli (UniPi: University of Pisa)H-Index: 51
Last. Piero Marchetti (UniPi: University of Pisa)H-Index: 93
view all 9 authors...
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