Masao Omata
University of Tokyo
CancerRadiologyEndocrinologySurgeryPathologyOncologyMolecular biologyVirologyCardiologyChemistryImmunologyHepatitis C virusHepatitis CCirrhosisHepatocellular carcinomaHepatologyCancer researchMedicineBiologyGastroenterology
1,312Publications
105H-index
42.2kCitations
Publications 1284
Newest
#1Guiqiang Wang (PKU: Peking University)H-Index: 12
#2Atsushi Tanaka (Teikyo University)H-Index: 31
Last. Shiv Kumar SarinH-Index: 70
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#1Naoki Akizue (Chiba University)H-Index: 2
#2Kenichiro Okimoto (Chiba University)H-Index: 11
Last. Naoya Kato (Chiba University)H-Index: 15
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Somatic mutations including the background mucosa in patients with Lugol-voiding lesions (LVLs) are still not well known. The aim of this study was to evaluate the somatic mutations of the background mucosa in patients with LVLs (Squamous cell carcinoma (SCC), intraepithelial neoplasia (IN), and hyperplasia). Twenty-five patients with LVLs (9 with SCC, 6 with IN, and 10 with hyperplasia) were included. A targeted sequence was performed for LVLs and background mucosa using an esophageal cancer pa...
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#1Kenji AmemiyaH-Index: 13
#2Yosuke HirotsuH-Index: 16
Last. Masao Omata (UTokyo: University of Tokyo)H-Index: 105
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Background Molecular testing is critical for identifying actionable variants in lung cancer for precision medicine. When tumor tissue samples are unavailable, archived cytological specimens (ACSs) can be used. The authors examined whether oncogenic variants could be accurately detected in ACSs versus paired formalin-fixed, paraffin-embedded (FFPE) tumor tissues with in vitro diagnostic tests. Methods The authors collected 18 ACSs and 15 FFPE tissues from 15 patients with lung cancer and investig...
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#1Rumi HiguchiH-Index: 5
#2Taichiro GotoH-Index: 17
Last. Masao OmataH-Index: 105
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#1Yosuke HirotsuH-Index: 16
#2Masao Omata (UTokyo: University of Tokyo)H-Index: 105
1 CitationsSource
#2Masao Omata (UTokyo: University of Tokyo)H-Index: 105
Abstract We aimed to investigate SARS-CoV-2 emerging lineage harboring variants in receptor binding domain (RBD) of spike protein in Japan. Total nucleic acids were subjected to whole genome sequencing on samples from 133 patients with coronavirus disease (COVID-19). We obtained the SARS-CoV-2 genome sequence from these patients and examined variants in RBD. As a result, three patients were infected with SARS-CoV-2 harboring E484K mutation in January 2021. These three patients were relatives; on...
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#1Yosuke HirotsuH-Index: 16
#2Makoto MaejimaH-Index: 5
Last. Masao Omata (UTokyo: University of Tokyo)H-Index: 105
view all 13 authors...
Abstract Background Reverse-transcription PCR (RT-PCR) is the gold standard for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection. Previously, we demonstrated the accuracy of the quantitative LUMIPULSE SARS-CoV-2 antigen test using samples collected retrospectively. Here, the antigen test was clinically validated using prospective samples. Methods A total of 1,033 nasopharyngeal swab samples were collected 1,033 individuals and an additional 275 follow-up samples were collec...
5 CitationsSource
#1Naoto NishiiH-Index: 3
#2Yosuke HirotsuH-Index: 16
Last. Masao OmataH-Index: 105
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BACKGROUND/AIM The definition of multiple oral cancers is based on the distances between the tumors. However, it is not possible to accurately predict tumor origins based only on clinical criteria. PATIENTS AND METHODS We performed whole-exome sequencing (WES) to analyze the genetic alterations in five tumors of two patients who underwent surgery in our hospital. RESULTS In case 1, the distances between tumors on the right mandibular gingiva and buccal mucosa were more than 15 mm, leading to a c...
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#1Yosuke HirotsuH-Index: 16
#2Makoto MaejimaH-Index: 5
Last. Masao Omata (UTokyo: University of Tokyo)H-Index: 105
view all 13 authors...
Various diagnostic tests utilizing different principles are currently under development for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, these tests can occasionally produce discrepant results, causing confusion in their interpretation. Here, we evaluated the performance and features of three diagnostic assays: quantitative reverse transcription polymerase chain reaction (RT-qPCR), FilmArray Respiratory Panel (RP) v2.1, and the LUMIPULSE antigen test. Twenty-seven seria...
7 CitationsSource