Vincenzo Mollace
Health Science University
Endothelial stem cellEndocrinologyChemistryApoptosisAutophagySuperoxide dismutaseOxidative stressHeart failureDiseaseMetabolic syndromeSuperoxideEndothelial dysfunctionReactive oxygen speciesNitric oxideBiochemistryPolyphenolMedicineBiologyCell biologyPharmacology
Publications 133
#1Elzbieta JandaH-Index: 18
#2Concetta MartinoH-Index: 4
Last. Jean A. BoutinH-Index: 48
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AIMS Diabetic cardiomyopathy represents the main cause of death among diabetic people. Despite this evidence, the molecular mechanisms triggered by impaired glucose and lipid metabolism inducing heart damage remain unclear. The aim of our study was to investigate the effect of altered metabolism on the early stages of cardiac injury in experimental diabetes. METHODS For this purpose, rats were fed a normocaloric diet (NPD) or a high fat diet (HFD) for up to 12 weeks. After the fourth week, strep...
3 CitationsSource
The high incidence of obesity is associated with an increasing risk of several chronic diseases such as cardiovascular disease, type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Sustained obesity is characterized by a chronic and unsolved inflammation of adipose tissue, which leads to a greater expression of proinflammatory adipokines, excessive lipid storage and adipogenesis. The purpose of this review is to clarify how inflammatory mediators act during adipose tissue dysfunction i...
#1Jessica MaiuoloH-Index: 18
#2Micaela GliozziH-Index: 17
Last. Vincenzo MollaceH-Index: 29
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Different bacterial families colonize most mucosal tissues in the human organism such as the skin, mouth, vagina, respiratory, and gastrointestinal districts. In particular, the mammalian intestine hosts a microbial community of between 1,000 and 1,500 bacterial species, collectively called "microbiota." Co-metabolism between the microbiota and the host system is generated and the symbiotic relationship is mutually beneficial. The balance that is achieved between the microbiota and the host orga...
1 CitationsSource
#1Elisabetta Ferraro (UniPi: University of Pisa)H-Index: 1
Last. Natalia MalaraH-Index: 20
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Despite the international scientific community’s commitment to improve clinical knowledge about coronavirus disease 2019 (COVID-19), knowledge regarding molecular details remains limited. In this review, we discuss hypoxia’s potential role in the pathogenesis of the maladaptive immune reaction against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The state of infection, with serious respiratory dysfunction, causes tissues to become hypoxic due to a discrepancy between cellular O2...
#1Cristina CarresiH-Index: 15
#1Cristina CarresiH-Index: 8
Last. Vincenzo MollaceH-Index: 29
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Atherothrombosis, a multifactorial and multistep artery disorder, represents one of the main causes of morbidity and mortality worldwide. The development and progression of atherothrombosis is closely associated with age, gender and a complex relationship between unhealthy lifestyle habits and several genetic risk factors. The imbalance between oxidative stress and antioxidant defenses is the main biological event leading to the development of a pro-oxidant phenotype, triggering cellular and mol...
1 CitationsSource
#1Daniel J. KlionskyH-Index: 122
Last. Chun Kit Tong (Hong Kong Baptist University)H-Index: 1
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29 CitationsSource
#1Giovanna Baron (University of Milan)H-Index: 5
#2Alessandra Altomare (University of Milan)H-Index: 13
Last. Giancarlo Aldini (University of Milan)H-Index: 52
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The aim of the study is to compare the qualitative and semi-quantitative profile of the polyphenol fraction purified from the leaf (BLPF) and fruit (BFPF) of bergamot (Citrus bergamia), and to evaluate their antioxidant and anti-inflammatory activity. The analytical qualitative profile was carried out by LC-ESI/MS using three different approaches: targeted (searching analytes already reported in bergamot extract), semi-targeted (a selective search of 3-hydroxy-3-methylglutarate [HMG] derivatives...
5 CitationsSource
#1Cristina CarresiH-Index: 15
#2Miriam ScicchitanoH-Index: 8
Last. Vincenzo MollaceH-Index: 29
view all 16 authors...
Cardiovascular diseases (CVDs), which include congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, and many other cardiac disorders, cause about 30% of deaths globally; representing one of the main health problems worldwide. Among CVDs, ischemic heart diseases (IHDs) are one of the major causes of morbidity and mortality in the world. The onset of IHDs is essentially due to an unbalance between the metabolic demands of the myocardium and its supply of ...