Silvia Scoccianti
University of Florence
Imaging phantomInternal medicineRadiologySurgeryMagnetic resonance imagingOncologyUnivariate analysisRetrospective cohort studyStage (cooking)Prospective cohort studyGlioblastomaChemotherapyTemozolomideConcomitantFotemustineRadiosurgeryNuclear medicineIn patientRadiation therapyBreast cancerMedicine
127Publications
19H-index
1,184Citations
Publications 128
Newest
#1Beatrice DettiH-Index: 20
#2Silvia ScocciantiH-Index: 19
Last. Lorenzo LiviH-Index: 28
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BACKGROUND High-grade gliomas are among the most aggressive central nervous system primary tumors, with a high risk of recurrence and a poor prognosis. Re-operation, re-irradiation, chemotherapy are options in this setting. No-best therapy has been established. Bevacizumab was approved on the basis of two Phase 2 trials that evaluated its efficacy in patients with recurrent glioblastoma. MATERIALS AND METHODS We have retrospectively review data of patients with high-grade glioma treated at our i...
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#1Silvia ScocciantiH-Index: 19
#2Emanuela OlmettoH-Index: 9
Last. Lorenzo LiviH-Index: 28
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BACKGROUND To define efficacy and toxicity of Immunotherapy (IT) with stereotactic radiotherapy (SRT) including radiosurgery (RS) or hypofractionated SRT (HFSRT) for brain metastases (BM) from Non-Small Cell Lung Cancer (NSCLC) in a multicentric retrospective study from AIRO (Italian Association of Radiotherapy and Clinical Oncology). METHODS NSCLC patients with BM receiving SRT+IT and treated in 19 Italian centers were analysed and compared with a control group of patients treated with exclusiv...
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#1Raj Singh (VCU: Virginia Commonwealth University)H-Index: 5
#2Eric J. Lehrer (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 14
Last. Joshua D. Palmer (The Ohio State University Wexner Medical Center)H-Index: 16
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ABSTRACT Background Limited evidence is available on the utility of dose-escalated radiation therapy (DE-RT) +/- (TMZ) vs. standard-of-care RT (SoC-RT) for patients with newly diagnosed glioblastoma multiforme (GBM). We performed a systematic review/meta-analysis to compare overall survival (OS) and progression-free survival (PFS) between DE-RT and SoC-RT. Methods We utilized a PICOS/PRISMA/MOOSE selection criterion to identify studies. The primary and secondary outcomes were 1-year OS and 1-yea...
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#1Giulio Francolini (UniFI: University of Florence)H-Index: 13
#2Isacco Desideri (UniFI: University of Florence)H-Index: 17
Last. Lorenzo Livi (UniFI: University of Florence)H-Index: 28
view all 14 authors...
BACKGROUND AND PURPOSE: COVID-19 constitutes a worldwide threat, prompting Italian Government to implement specific measures on March 8, 2020, to protect patients and health workers from disease transmission. The impact of preventive measures on daily activity of a radiotherapy facility may hamper the ability to fulfill normal workload burden. Thus, we assessed the number of delivered treatments in a specific observation period after the adoption of preventive measures (since March 11 to April 2...
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#1Cinzia MazziniH-Index: 3
#2Giulia PierettiH-Index: 3
Last. Gianni VirgiliH-Index: 45
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We retrospectively analyzed data from records of 48 patients (48 eyes) treated with gamma-knife (n = 18) or Ruthenium-106 brachytherapy (n = 30) for uveal melanoma, in our Ocular Oncology Unit between December 2013 and September 2019, with the aim to evaluate treatment outcomes, and incidence and risk factors for secondary glaucoma. Patients demographics and tumor characteristics at diagnosis were recorded. Follow-up data were collected regarding local tumor control, treatment complications, enu...
1 CitationsSource
#2Stefania Volpe (IEO: European Institute of Oncology)H-Index: 9
Last. Stefano Arcangeli (University of Milan)H-Index: 24
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PURPOSE To perform a systematic review of the current level of evidence on post-operative management following brain metastasectomy (namely: adjuvant stereotactic radiosurgery, whole brain radiotherapy or observation), and to propose a GRADE-based dedicated recommendation to inform Radiation Oncologists' clinical practice. METHODS A panel of expert Radiation Oncologists from the Italian Association of Radiotherapy and Clinical Oncology had defined the search question per the PICO methodology. El...
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#1Beatrice DettiH-Index: 20
#2Silvia ScocciantiH-Index: 19
Last. Lorenzo LiviH-Index: 28
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GBM (glioblastoma multiforme) is the most common and aggressive brain tumor. To date, treatment options for glioblastoma recurrence are lacking. Recently, REGOMA trial showed the superiority of regorafenib to lomustine in patients with first glioblastoma recurrence. We report an excellent response to three months treatment with regorafenib, in a patient who presented a rapid progression after the end of post operative radio-chemotherapy and after only one cycle of adjuvant TMZ (Temozolomide).
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#1Silvia ScocciantiH-Index: 19
#2Marco PernaH-Index: 5
Last. Lorenzo LiviH-Index: 28
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In case of circumscribed recurrent glioblastoma (rec-GBM), a second surgery (Re-S) and reirradiation (Re-RT) are local strategies to consider. The aim is to provide an algorithm to use in the daily clinical practice. The first step is to consider the life expectancy in order to establish whether the patient should be a candidate for active treatment. In case of a relatively good life expectancy (>3 months) and a confirmed circumscribed disease(i.e. without multiple lesions that are in different ...
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#1Pierina NavarriaH-Index: 25
#2Giuseppe MinnitiH-Index: 53
Last. Marta Scorsetti (Humanitas University)H-Index: 45
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Objectives:The prognosis of brain metastatic colorectal cancer patients (BMCRC) is poor. Several local treatments have been used, but the optimal treatment choice remains an unresolved issue. We ev...
1 CitationsSource
#1Emanuela OlmettoH-Index: 9
#2Silvia ScocciantiH-Index: 19
Last. Vieri ScottiH-Index: 19
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