Fernando Martínez-Valle
Autonomous University of Barcelona
Internal medicineRadiologyPhenotypeSurgeryPathologyAntibodyAutoantibodyCardiologyRetrospective cohort studyIntensive care medicineAdverse effectRheumatologyCohort studyImmunologyObservational studyBiopsyVasculitisHepatitisLiver diseaseEosinophiliaAutoimmune hepatitisImmunotherapyPancreasDiseaseTakayasu's arteritisMalignancyAmyloidosisIgG4-related diseaseFibrosisRituximabIdiopathic Retroperitoneal FibrosisGynecologyCoronavirus disease 2019 (COVID-19)In patientHead and neckClinical trialMedicineCohortAmyloidImmune systemGastroenterology
43Publications
9H-index
277Citations
Publications 43
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#1Marco Lanzillotta (UniSR: Vita-Salute San Raffaele University)H-Index: 16
#2Andreu Fernández-Codina (UWO: University of Western Ontario)H-Index: 10
Last. Emanuel Della-Torre (UniSR: Vita-Salute San Raffaele University)H-Index: 27
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INTRODUCTION Awareness of IgG4-related disease (IgG4-RD) is increasing worldwide and specialists are now familiar with most of its clinical manifestations and mimickers. IgG4-RD promptly responds to glucocorticoids and repeated courses are typically used to induce and maintain remission because the disease relapses in most patients. If left untreated it can lead to organ dysfunction, organ failure and death. Advancement in our understanding of IgG4-RD pathogenesis is leading to the identificatio...
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#1Jose Loureiro-Amigo (Autonomous University of Barcelona)H-Index: 1
Last. Roser Solans-Laqué (Autonomous University of Barcelona)H-Index: 21
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BACKGROUND blood B cell profile has been proposed to have diagnostic utility in primary Sjogren syndrome (pSS), but the potential utility of advanced lymphocyte profiling to differentiate between pSS and Sicca syndrome has not been fully investigated. METHODS distribution of peripheral lymphocyte subpopulations was analysed by flow cytometry in 68 patients with pSS, 26 patients with Sicca syndrome and 23 healthy controls. The ability to discriminate between pSS and Sicca syndrome was analysed us...
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#1Olimpia Orozco-Gálvez (UWO: University of Western Ontario)
Last. Fernando Martínez-ValleH-Index: 9
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OBJECTIVE The aim of this study was to assess disease activity by different PET/CT measurements in IgG4-related disease (IgG4-RD) flares and their correlation with the IgG4-RD responder index (IgG4-RI). PATIENTS AND METHODS Patients were retrospectively recruited from a single center in Barcelona, Spain. They all had IgG4-RD flares with an 18F-FDG PET/CT examination performed within the 2 first weeks of the flare onset and another one after at least 3 months of treatment between 2012 and 2018. E...
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#1Andreu Fernández-Codina (UWO: University of Western Ontario)H-Index: 10
#2Blanca Pinilla (Hospital General Universitario Gregorio Marañón)H-Index: 9
Last. Fernando Martínez-ValleH-Index: 9
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OBJECTIVES Several IgG4-related disease (IgG4-RD) phenotypes have been proposed and the first set of classification criteria have been recently created. Our objectives were to assess the phenotype distribution and the performance of the classification criteria in Spanish patients as genetic and geographical differences may exist. METHODS We performed a cross-sectional multicentre study (Registro Espanol de Enfermedad Relacionada con la IgG4, REERIGG4) with nine participating centres from Spain. ...
1 CitationsSource
#1Mar Riveiro-Barciela (Autonomous University of Barcelona)H-Index: 15
#2Moises Labrador-Horrillo (Autonomous University of Barcelona)H-Index: 20
Last. Fernando Martínez-Valle (Autonomous University of Barcelona)H-Index: 9
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Background and aims Identification of SARS-CoV-2-infected patients at high-risk of poor prognosis is crucial. We aimed to establish predictive models for COVID-19 pneumonia severity in hospitalized patients. Methods Retrospective study of 430 patients admitted in Vall d’Hebron Hospital (Barcelona) between 03-12-2020 and 04-28-2020 due to COVID-19 pneumonia. Two models to identify the patients who required high-flow-oxygen-support were generated, one using baseline data and another with also foll...
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#1Mar Riveiro-Barciela (Autonomous University of Barcelona)H-Index: 15
Last. Eva Muñoz-CouseloH-Index: 16
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Abstract In recent years, immunotherapy has become an important pillar of cancer treatment, with high response rates regardless of tumour histology or baseline mutations. However, immune activation associated with check-point inhibitors is not selective and a large variety of immune-related adverse events have been associated with anti-PD1, anti-PD-1/L-1 and anti-CTLA-4 agents. Though diagnosis and treatment of these toxicities have been established according to the recommendations from clinical...
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Last. Fernando Martínez-ValleH-Index: 9
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IgG4-related disease (IgG4-RD) is an autoimmune fibrosing condition which is being increasingly recognized. This condition has been classically managed with glucocorticoids (GC) with variable dosing and frequent relapses. Multiple observational reports studied different GC doses and steroid-sparing agents. Rituximab (RTX) was reported as an effective induction treatment, with less relapses after 1 year of treatment. In the absence of guidelines, an international management consensus was made in ...
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#1Mar Riveiro-Barciela (ISCIII: Carlos III Health Institute)H-Index: 15
#2Ana Barreira-DíazH-Index: 2
Last. M. Buti (ISCIII: Carlos III Health Institute)H-Index: 16
view all 11 authors...
BACKGROUND & AIMS: Check point inhibitors (CPI) have improved survival of oncology patients but adverse effects that mimic autoimmune disorders have been reported. Our aim was describe the characteristics of immune-related hepatitis (irH) and prognosis, and compared them to those of patients with autoimmune hepatitis (AIH). METHODS: this a retrospective study including all grade >/= 3 (severe) irH diagnosed among 414 patients treated with CPI from 2016 to 2018. RESULTS: 28 cases of severe irH we...
5 CitationsSource
#1Andreu Fernández-Codina (UWO: University of Western Ontario)H-Index: 10
#2Blanca Pinilla (Hospital General Universitario Gregorio Marañón)H-Index: 9
view all 15 authors...
Resume Contexte La maladie associee aux IgG4 (MAG-4) est une maladie auto-immune qui declenche une cascade inflammatoire aboutissant a une fibrose. Les criteres d’evaluation sont limites et les options therapeutiques insuffisamment explorees. Objectifs Evaluer la variation du score d’activite de la MAG-4 (IgG4-RI) dans une cohorte de patients atteints et explorer leurs traitements et resultats. Methodes Nous avons etudie le phenotype clinique, la gravite de la maladie et la reponse au traitement...
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