Ferry P.W. Melchels
Heriot-Watt University
Self-healing hydrogelsBiomedical engineeringMatrix (biology)Regeneration (biology)NanotechnologyChemistryPolymer chemistryMaterials scienceGelatinStereolithography3D bioprintingPolycaprolactoneRapid prototypingBiofabricationChondrogenesisTissue engineering3D printingPorosityMedicineScaffold
100Publications
31H-index
7,100Citations
Publications 87
Newest
Single-administration vaccine delivery systems are intended to improve the efficiency and efficacy of immunisation programs in both human and veterinary medicine. In this work, an osmotically triggered delayed delivery device was developed that was able to release a payload after a delay of approximately 21 days, in a consistent and reproducible manner. The device was constructed out of a flexible poly(e-caprolactone) photo-cured network fabricated into a hollow tubular shape, which expelled app...
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#1Amin Shavandi (ULB: Université libre de Bruxelles)H-Index: 15
#2Soraya Hosseini (CCU: National Chung Cheng University)H-Index: 16
Last. Ferry P.W. Melchels (Heriot-Watt University)H-Index: 31
view all 6 authors...
The interest in bioprinting of sustainable biomaterials is rapidly growing, and lignocellulosic biomaterials have a unique role in this development. Lignocellulosic materials are biocompatible and possess tunable mechanical properties, and therefore promising for use in the field of 3D-printed biomaterials. This review aims to spotlight the recent progress on the application of different lignocellulosic materials (cellulose, hemicellulose, and lignin) from various sources (wood, bacteria, and fu...
4 CitationsSource
#1Ana C. Fonseca (UC: University of Coimbra)H-Index: 16
#2Ferry P.W. Melchels (Heriot-Watt University)H-Index: 31
Last. Marco Domingos (University of Manchester)H-Index: 18
view all 8 authors...
The lack of in vitro tissue and organ models capable of mimicking human physiology severely hinders the development and clinical translation of therapies and drugs with higher in vivo efficacy. Bioprinting allow us to fill this gap and generate 3D tissue analogues with complex functional and structural organization through the precise spatial positioning of multiple materials and cells. In this review, we report the latest developments in terms of bioprinting technologies for the manufacturing o...
5 CitationsSource
#1Alberto Di Bartolo (Heriot-Watt University)H-Index: 2
#1Alberto Di Bartolo (Heriot-Watt University)H-Index: 1
Last. Ferry P.W. Melchels (Heriot-Watt University)H-Index: 31
view all 2 authors...
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#1Andrew McCormack (Heriot-Watt University)H-Index: 1
#2Christopher B. Highley (UVA: University of Virginia)H-Index: 21
Last. Ferry P.W. Melchels (Heriot-Watt University)H-Index: 31
view all 4 authors...
Extrusion-based 3D printers have been adopted in pursuit of engineering functional tissues through 3D bioprinting. However, we are still a long way from the promise of fabricating constructs approaching the complexity and function of native tissues. A major challenge is presented by the competing requirements of biomimicry and manufacturability. This opinion article discusses 3D printing in suspension baths as a novel strategy capable of disrupting the current bioprinting landscape. Suspension b...
37 CitationsSource
#1Jetze VisserH-Index: 16
#2Ferry P.W. MelchelsH-Index: 31
Last. Jos MaldaH-Index: 52
view all 5 authors...
5 years ago, we described the emergence of 3D printing in medicine. It was about 3D printing of anatomical structures, patient-specific drilling guides, cutting templates and implants and printing of living cells, growth factors and biomaterials ('bioprinting'). Surgeons are increasingly making use of 3D printing possibilities in preparation of surgeries on patients with complicated anatomies. Using tangible 3D models, it is easier for surgeons to prepare for surgeries and discussions with patie...
#1Khoon S. Lim (University of Otago)H-Index: 17
#2Barbara J. Klotz (UU: Utrecht University)H-Index: 4
Last. Tim B. F. Woodfield (University of Otago)H-Index: 32
view all 8 authors...
In this study, the cyto-compatibility and cellular functionality of cell-laden gelatin-methacryloyl (Gel-MA) hydrogels fabricated using a set of photo-initiators which absorb in 400-450 nm of the visible light range are investigated. Gel-MA hydrogels cross-linked using ruthenium (Ru) and sodium persulfate (SPS), are characterized to have comparable physico-mechanical properties as Gel-MA gels photo-polymerized using more conventionally adopted photo-initiators, such as 1-[4-(2-hydroxyethoxy)-phe...
32 CitationsSource
#1Jetze VisserH-Index: 16
#2Ferry P.W. Melchels (Heriot-Watt University)H-Index: 31
Last. Jos MaldaH-Index: 52
view all 5 authors...
5 years ago, we described the emergence of 3D printing in medicine. It was about 3D printing of anatomical structures, patient-specific drilling guides, cutting templates and implants and printing of living cells, growth factors and biomaterials ('bioprinting'). Surgeons are increasingly making use of 3D printing possibilities in preparation of surgeries on patients with complicated anatomies. Using tangible 3D models, it is easier for surgeons to prepare for surgeries and discussions with patie...
1 Citations
#1Ferry P.W. MelchelsH-Index: 31
#2Jayne Hope (The Roslin Institute)
Last. Vicki StoneH-Index: 63
view all 3 authors...
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#1Barbara J. KlotzH-Index: 4
#2Khoon S. LimH-Index: 17
Last. Debby GawlittaH-Index: 27
view all 10 authors...
In engineering of tissue analogues, upscaling to clinically-relevant sized constructs remains a significant challenge. The successful integration of a vascular network throughout the engineered tissue is anticipated to overcome the lack of nutrient and oxygen supply to residing cells. This work aimed at developing a multiscale bone-tissue-specific vascularisation strategy. Engineering pre-vascularised bone leads to biological and fabrication dilemmas. To fabricate channels endowed with an endoth...
16 CitationsSource