Matthew P. Pase
Monash University, Clayton campus
Framingham Heart StudyFramingham Risk ScoreInternal medicineCardiologyRandomized controlled trialCognitionEffects of sleep deprivation on cognitive performancePhysical therapyCohort studyHazard ratioArterial stiffnessPulse wave velocityDementiaCognitive declineAortic stiffnessStrokeMedicineCohortGerontologyBlood pressure
113Publications
28H-index
1,819Citations
Publications 121
Newest
#1A Baril (BU: Boston University)H-Index: 1
#2Alexa Beiser (BU: Boston University)H-Index: 94
Last. Jayandra J. Himali (University of Texas Health Science Center at San Antonio)
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Objective: To test the hypothesis that reduced slow-wave sleep, or N3 sleep, which is thought to underlie the restorative functions of sleep, is associated with MRI markers of brain aging, we evaluated this relationship in the community-based Framingham Heart Study Offspring cohort using polysomnography and brain MRI. Methods: We studied 492 participants (58.8 ± 8.8 years, 49.4% male) free of neurological diseases who completed a brain MRI scan and in-home overnight polysomnography to assess slo...
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#1Jayandra J. HimaliH-Index: 32
#2Alexa Beiser (BU: Boston University)H-Index: 94
Last. Matthew P. Pase (Harvard University)H-Index: 28
view all 5 authors...
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#1Andrée-Ann BarilH-Index: 8
#2Alexa BeiserH-Index: 94
Last. Matthew P. PaseH-Index: 28
view all 8 authors...
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#1Andrée-Ann BarilH-Index: 8
#2Alexa BeiserH-Index: 94
Last. Jayandra J. Himali (University of Texas Health Science Center at San Antonio)
view all 8 authors...
Source
#1Yen Ying Lim (Florey Institute of Neuroscience and Mental Health)H-Index: 32
#2Stephanie Perin (Florey Institute of Neuroscience and Mental Health)
Last. Paul MaruffH-Index: 77
view all 8 authors...
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#1Matthew P. Pase (Harvard University)H-Index: 28
#2Jayandra J. Himali (BU: Boston University)H-Index: 32
Last. Sudha SeshadriH-Index: 95
view all 15 authors...
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#1Emer R. McGrath (National University of Ireland, Galway)H-Index: 10
#2Jayandra J. HimaliH-Index: 32
Last. Sudha Seshadri (University of Texas at Austin)H-Index: 95
view all 13 authors...
Background GDF15 (growth differentiation factor 15) and NT-proBNP (N-terminal pro-B-type natriuretic peptide) may offer promise as biomarkers for cognitive outcomes, including dementia. We determined the association of these biomarkers with cognitive outcomes in a community-based cohort. Methods and Results Plasma GDF15 (n=1603) and NT-proBNP levels (n=1590) (53% women; mean age, 68.7 years) were measured in dementia-free Framingham Offspring cohort participants at examination 7 (1998-2001). Par...
1 CitationsSource
#1Elie Gottlieb (University of Melbourne)H-Index: 1
#2Leonid Churilov (University of Melbourne)H-Index: 38
Last. Amy Brodtmann (University of Melbourne)H-Index: 22
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#1Elie Gottlieb (University of Melbourne)H-Index: 1
#2Natalia Egorova (University of Melbourne)H-Index: 16
Last. Amy Brodtmann (University of Melbourne)H-Index: 22
view all 8 authors...
Sleep-wake disruption is a key modifiable risk factor and sequela of stroke. The pathogenesis of post-stroke sleep dysfunction is unclear. It is not known whether post-stroke sleep pathology is due to focal infarction to sleep-wake hubs, or to accelerated post-stroke neurodegeneration in subcortical structures after stroke. We characterise the first prospective post-stroke regional brain volumetric and whole-brain, fibre-specific, white matter markers of objectively measured sleep-wake dysfuncti...
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#1Gina M. Peloso (BU: Boston University)H-Index: 51
#2Alexa S. Beiser (BU: Boston University)H-Index: 3
Last. Sudha Seshadri (University of Texas at Austin)H-Index: 95
view all 8 authors...
Objective. To determine the joint role of ideal cardiovascular health (CVH) and genetic risk on risk of dementia. Methods. We categorized CVH based on the American Heart Association Ideal CVH Index and genetic risk through a genetic risk score (GRS) of common genetic variants as well as the APOE e4 genotype in 1,211 Framingham Heart Study (FHS) offspring cohort participants. We used multivariable Cox proportional hazards regression models to examine the association between CVH, genetic risk, and...
3 CitationsSource
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