Marco Volante
University of Turin
CancerInternal medicineEndocrinologyPathologyOncologyChemistryImmunohistochemistryPathologicalLung cancerMitotaneCarcinomaLungNeuroendocrine tumorsAdenocarcinomaAdrenocortical carcinomaThyroid carcinomaCancer researchThyroidMedicineBiology
Publications 348
#1Enrico Costantino Falco (UNITO: University of Turin)H-Index: 1
#2Lorenzo DanieleH-Index: 15
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
view all 7 authors...
Ectopic adrenal rests are a rare condition which can be found in various sites, generally in the retroperitoneum or pelvis along the path of gonadal descent. Their real prevalence is unknown. Males are more commonly affected, at least in the pediatric age. Adrenal rests are usually clinically silent and incidentally found in surgical samples, mostly in the pediatric population, and rarely in adults. With the aim of increasing knowledge and estimating the prevalence of ectopic adrenocortical tiss...
#1Umberto Malapelle (University of Naples Federico II)H-Index: 29
#2Pasquale Pisapia (University of Naples Federico II)H-Index: 17
Last. Giancarlo Troncone (University of Naples Federico II)H-Index: 55
view all 29 authors...
AIMS: Lung cancer predictive biomarker testing is essential to select advanced-stage patients for targeted treatments and should be carried out without delays even during health emergencies, such as the coronavirus (COVID-19) outbreak. METHODS: Fifteen molecular laboratories from seven different European countries compared 4 weeks of national lockdown to a corresponding period in 2019, in terms of tissue and/or plasma-based molecular test workload, analytical platforms adopted, number of cases u...
15 CitationsSource
Intrathyroidal thymic carcinoma (ITC) is a rare thyroid tumor that resembles thymic carcinoma, for which there are no recommendations on diagnostic and therapeutic approaches. We performed a pooled analysis of published ITC cases to describe the natural history of this disease and identify prognostic factors. We performed a systematic review of histopathological-confirmed ITC cases published in the English literature. The following keywords were used: "intrathyroidal thymic carcinoma", "carcinom...
#1Francesca Napoli (UNITO: University of Turin)H-Index: 8
#2Angela ListìH-Index: 3
Last. Luisella Righi (UNITO: University of Turin)H-Index: 33
view all 9 authors...
Malignant pleural mesothelioma (MPM) is a rare and highly aggressive disease that arises from pleural mesothelial cells, characterized by a median survival of approximately 13–15 months after diagnosis. The primary cause of this disease is asbestos exposure and the main issues associated with it are late diagnosis and lack of effective therapies. Asbestos-induced cellular damage is associated with the generation of an inflammatory microenvironment that influences and supports tumor growth, possi...
#1Marco VolanteH-Index: 71
#2Ida RapaH-Index: 22
Last. Mauro PapottiH-Index: 98
view all 8 authors...
The molecular mechanisms of adrenocortical carcinoma development are incompletely defined. De-regulation of cellular-to-extracellular matrix interactions and angiogenesis appear among mechanisms associated to the malignant phenotype. Our aim was to investigate, employing PCR-based array profiling, 157 molecules involved in cell-to-matrix interactions and angiogenesis in a frozen series of 6 benign and 6 malignant adrenocortical neoplasms, to identify novel pathogenetic markers. In 14 genes, a si...
1 CitationsSource
#1Giovanna Carrà (UNITO: University of Turin)H-Index: 12
#2Giuseppe Ermondi (UNITO: University of Turin)H-Index: 23
Last. Alessandro Morotti (UNITO: University of Turin)H-Index: 19
view all 17 authors...
BACKGROUND Oxidative stress is a hallmark of many cancers. The increment in reactive oxygen species (ROS), resulting from an increased mitochondrial respiration, is the major cause of oxidative stress. Cell fate is known to be intricately linked to the amount of ROS produced. The direct generation of ROS is also one of the mechanisms exploited by common anticancer therapies, such as chemotherapy. METHODS We assessed the role of NFKBIA with various approaches, including in silico analyses, RNA-si...
#1Federica Massa (UNITO: University of Turin)H-Index: 8
#2P. CaraciH-Index: 8
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
view all 6 authors...
The clinical impact of the SIAPEC/SIE 2014 classification for thyroid cytology has been addressed in few studies that evaluated the malignancy rate and the relative prevalence of each category. No study analyzed its intra-observer and inter-observer reproducibility, so far. We retrospectively collected all “indeterminate” lesions diagnosed before (2011–2014) and after (2015–2018) the application of the SIAPEC/SIE 2014 classification at our Institution. Their relative malignancy risks were calcul...
1 CitationsSource
#1Thomas J. Giordano (UM: University of Michigan)H-Index: 95
#2Daniel M. Berney (Barts Health NHS Trust)H-Index: 66
Last. Anthony J. Gill (Kolling Institute of Medical Research)H-Index: 73
view all 12 authors...
Summay Complete resection of adrenal cortical carcinoma (ACC) with or without adjuvant therapy offers the best outcome. Recurrence is common, and in individual cases, the long-term outcome is difficult to predict, making it challenging to personalize treatment options. Current risk stratification approaches are based on clinical and conventional surgical pathology assessment. Rigorous and uniform pathological assessment may improve care for individual patients and facilitate multi-institutional ...
3 CitationsSource
#1Philippe ThuillierH-Index: 1
#2Virginia LiberiniH-Index: 2
Last. Désirée DeandreisH-Index: 30
view all 11 authors...
Aim: To evaluate if conventional Positron emission tomography (PET) parameters and radiomic features (RFs) extracted by 18F-FDG-PET/CT can differentiate among different histological subtypes of lung neuroendocrine neoplasms (Lu-NENs). Methods: Forty-four naive-treatment patients on whom 18F-FDG-PET/CT was performed for histologically confirmed Lu-NEN (n = 46) were retrospectively included. Manual segmentation was performed by two operators allowing for extraction of four conventional PET paramet...
1 CitationsSource
#1Beatrice ParmaH-Index: 1
#1B. Parma (University of Leeds)
Last. Paolo CeppiH-Index: 6
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The identification of novel targets is of paramount importance to develop more effective drugs and improve the treatment of non-small cell lung cancer (NSCLC), the leading cause of cancer-related deaths worldwide. Since cells alter their metabolic rewiring during tumorigenesis and along cancer progression, targeting key metabolic players and metabolism-associated proteins represents a valuable approach with a high therapeutic potential. Metabolic fitness relies on the functionality of heat shock...