M. Lazzaroni
University of Brescia
Internal medicineEndocrinologySurgeryRandomized controlled trialPlaceboHelicobacter pyloriChemotherapyDuodenumOral administrationRanitidineOmeprazoleGastric acidEndoscopyStomachCimetidineDuodenal ulcerHistamine H2 receptorAnesthesiaMedicineGastroenterology
Publications 117
#1Andrea CassinottiH-Index: 25
#2Satish Keshav (John Radcliffe Hospital)H-Index: 34
Last. Simon Travis (John Radcliffe Hospital)H-Index: 87
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Background and aims: The National UK IBD audit tool is an electronic database created to improve the quality and safety of care for IBD patients by auditing individual patient care, service resources and organisation against national standards. We used the National UK IBD audit tool to compare the organisation and process of IBD care between services in Oxford (UK) and Milan (Italy), as a pilot study to evaluate its application outside national boundaries. Methods: Clinical and demographic data ...
17 CitationsSource
OBJECTIVES: The human leukocyte antigen (HLA) system includes genes involved in graft-vs-host rejection and in immune response. The discovery that HLAs are associated with several diseases led to appealing developments both in basic biomedical research and in clinical medicine, and offered the opportunity to improve the understanding of pathogenesis and classification of diseases, as well as to provide diagnostic and prognostic indicators. The aim of this article is to review the association bet...
76 CitationsSource
#1Diego Foschi (University of Milan)H-Index: 25
#2M. LazzaroniH-Index: 20
Last. G. Bianchi Porro (University of Milan)H-Index: 61
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Abstract Background Intraparietal gastric administration of Botulinum Toxin A has been studied in open trials to induce satiety and increase weight loss of obese patients with contradictory results. In previous studies only the antrum was the target for Botulinum Toxin A, whereas the fundus, which exerts important activity on gastric accommodation, was excluded. In this study we report the effects of injection into both gastric regions on solid gastric capacity and emptying of the stomach. Mater...
23 CitationsSource
#1M. LazzaroniH-Index: 20
#2A. BattocchiaH-Index: 2
Last. G. Bianchi PorroH-Index: 61
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Abstract Although adverse effects of nonsteroidal anti-inflammatory drugs occur in only a small proportion of users, the widespread use of these drugs has resulted in a substantial overall number of affected persons who experience serious gastrointestinal complications. Dyspeptic symptoms are estimated to occur in 10–60% of nonsteroidal anti-inflammatory drug users and lead to discontinuation of treatment in 5–15% of rheumatoid arthritis patients taking nonsteroidal anti-inflammatory drugs. It i...
18 CitationsSource
#1S. GrecoH-Index: 16
#2Giovanni MaconiH-Index: 56
Last. Gabriele Bianchi PorroH-Index: 40
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A 45-year-old Italian man, living in Italy, was admitted to our clinic with a 6-month history of chronic diarrhoea (soft stool, 3–4 times/day), iron-deficiency anaemia, recurrent abdominal pain, weight loss (10 kg over 6 months) and weakness. Examination was normal apart from moderate pallor and a soft but diffusely tender abdomen. He was not febrile: there was no pathological sign apart from increased bowel sounds. Other investigations showed haemoglobin 10.8 g/dl, …
#1M. LazzaroniH-Index: 20
#2M. PetrilloH-Index: 17
Last. G. Bianchi PorroH-Index: 61
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SUMMARY This placebo-controlled study assessed the efficacy and tolerability of polyethylene glycol-electrolyte lavage solution (PEG-ELS), with and without simethicone, in the preparation of patients with inflammatory bowel disease for colonoscopy. PEG-ELS 4 L plus placebo, or PEG-ELS 4 L plus simethicone 120 mg, was administered according to a randomized double-blind protocol to 115 patients with ulcerative colitis or Crohn's disease. The parameters assessed were: presence of bubbles, degree of...
65 CitationsSource
#1M. LazzaroniH-Index: 20
#2Enzo GrossiH-Index: 43
Last. G. Bianchi PorroH-Index: 61
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SUMMARY The aim of this study was to compare the effects upon gastric secretion of therapeutic doses of aminophylline, with doxofylline, a new xanthine derivative proposed for the treatment of chronic asthma. Twelve patients with endoscopically-proven healed duodenal ulcer were studied twice under double-blind conditions in cross-over experiments. In a 1-hour infusion, six patients received either 240 mg aminophylline i.v. or 200 mg doxofylline i.v., and six received either 240 mg aminophylline ...
17 CitationsSource
#1M. LazzaroniH-Index: 20
#2A. CanaliH-Index: 1
Last. G. Bianchi PorroH-Index: 61
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SUMMARY Aim: To compare the efficacy and tolerability of early evening (19.00–21.00 hours) vs. bedtime (22.00–00.00 hours) oral administration of roxatidine 150 mg in the short-term treatment of active duodenal ulcer. Methods: The trial was randomized, double-blind and double-dummy, with parallel groups. A total of 276 patients were recruited and randomly assigned either to roxatidine in the early evening (n= 139) or roxatidine at bedtime (n= 137). Results: After 4 weeks, 78% of patients receivi...
#1G. Bianchi PorroH-Index: 61
#2M. LazzaroniH-Index: 20
Last. A. CalacroH-Index: 1
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SUMMARY A 24-week, double-blind, randomized study at 13 centres compared the efficacy and safety of 20 mg famotidine nocte and 150 mg ranitidine h.s. for the prevention of duodenal ulcer recurrence. All participants had been successfully treated for an acute duodenal ulcer with 40 mg famotidine nocte. Patients were endoscoped at baseline and at 24 weeks, unless symptoms warranted earlier examination: of the 208 patients enrolled, 86 who received famotidine and 84 who received ranitidine met all ...
7 CitationsSource
#1G. Bianchi PorroH-Index: 61
#2Roberto CorinaldesiH-Index: 60
Last. E. Bolling (Astra)H-Index: 2
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SUMMARY Background: The aim of this study was to compare omeprazole 10 mg o.m. (daily) with omeprazole 20 mg o.m. on Friday to Sunday inclusive (weekend) in the prevention of duodenal ulcer relapse over a 6-month period. Methods: After an open healing phase (4 to 8 weeks) with omeprazole 20 mg o.m., 81 patients entered the follow-up phase. Forty-two were randomized in a double-blind double-dummy technique, to omeprazole 10 mg o.m., and 39 to omeprazole 20 mg at weekends, At 3 and 6 months or on ...
5 CitationsSource